Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
GI, Liver & Pancreas Pathology
1. Immunohistochemical Expression of CDX2 in Gastric Carcinoma

Avan Sardar Ahmed; Jalal Ali Jalal; Kalthuma Salih Hamad Ameen

Volume 17, Issue 2 , April 2022, , Pages 143-149

http://dx.doi.org/10.30699/ijp.2022.530631.2648

Abstract
  Background & Objective: Gastric cancer (GC) persists to be a major health issue globally, and the need to investigate new molecular markers for improving the survival of patients continues. CDX2 is a homeobox caudal protein family member encoded by the CDX2 gene and is probably playing a role in ...  Read More

GI, Liver & Pancreas Pathology
2. Clinicopathological Significance of PTEN Expression and Its Prognostic Effect in Colorectal Adenocarcinoma Patients

Zohreh Mirzapour Abbas abadi; Fatemeh Samiee Rad; Dariush Hamedi Asl; Babak Rahmani; Mahmood Soleimani Dodaran; Amir Peimani

Volume 17, Issue 2 , April 2022, , Pages 150-158

http://dx.doi.org/10.30699/ijp.2021.531779.2653

Abstract
  Background & Objective: Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene located at chromosome 10. PTEN is a regulator of the PI3K/AKT signaling pathway that inhibits cell proliferation and promotes apoptosis. PTEN loss of function occurs in a spectrum  of cancers, including ...  Read More

GI, Liver & Pancreas Pathology
3. Quantity and Distribution of Eosinophils in the Adult Human Gastric Specimens

Behrang Kazeminezhad; Helia Falahatian Mehrjardi; Afshin Moradi; Tahmineh Mollasharifi

Volume 17, Issue 2 , April 2022, , Pages 166-173

http://dx.doi.org/10.30699/ijp.2022.537842.2706

Abstract
  Background & Objective: The existence of eosinophils in the gastric mucosal epithelium is unusual, while the term "eosinophilic gastritis" has become overused due to the increased numbers of eosinophils found in gastric specimens. Thus, we aimed to assess the number and distribution of eosinophils ...  Read More

GI, Liver & Pancreas Pathology
4. Immunohistochemical Expression of Stanniocalcin 2 in Colorectal Cancer: A Retrospective Egyptian Study

Hala M. El-hanbuli; Rehab S. Galal; Mohammed F. Darweesh; Mohamed H. Elmahdi

Volume 17, Issue 1 , January 2022, , Pages 15-22

http://dx.doi.org/10.30699/ijp.2021.521799.2559

Abstract
  Background & Objective: Colorectal cancer is the third most common cause of cancer death worldwide. Stanniocalcin 2 (STC2) is a glycoprotein hormone over-expressed in many human cancers where it regulates tumor progression and invasion. Evaluating its expression in colorectal cancer and its relation ...  Read More

GI, Liver & Pancreas Pathology
5. Kindlin1 As a Sex and Location Specific Diagnostic Marker in Gastric Cancer Patients

Mohammad Reza Abbaszadegan; Negin Taghehchian; Azadeh Aarabi; Sohrab Nozari; Ehsan Saburi; Meysam Moghbeli

Volume 17, Issue 1 , January 2022, , Pages 23-28

http://dx.doi.org/10.30699/ijp.2021.526950.2603

Abstract
  Background & Objective: Gastric cancer (GC) is considered one of the main reasons for cancer-related mortalities among Iranians. Kindlin-1 is an adhesion protein member of integrin-interacting proteins, regulating integrin activation through direct interaction with β-integrin. Therefore, kindlin-1 ...  Read More

GI, Liver & Pancreas Pathology
6. LncRNA SNHG6 Silencing Could Arrest Progression of High Grade Colorectal Cancers

Amin Jafari Oliayi; Shahriar dabiri; Malek Hossein Asadi

Volume 17, Issue 1 , January 2022, , Pages 29-36

http://dx.doi.org/10.30699/ijp.2021.527781.2610

Abstract
  Background & Objective: Colorectal cancer (CRC), like other cancers, needs faster and more accurate identifications. A well-timed prognosis of CRC could be an important turning point in the survival of patients. Supplementary signs, such as long non-coding RNAs (lncRNAs), could be helpful for this ...  Read More

GI, Liver & Pancreas Pathology
7. Annexin Expression in Cholangiocarcinoma, and Metastatic Pancreatic Ductal Adenocarcinoma “Is it be Helpful for Differential Diagnosis of These Tumors in the Liver?”

Bita Geramizadeh; Mahsa Sehat; Azam Mehrmozayan; Alireza Shojazadeh

Volume 16, Issue 4 , August 2021, , Pages 433-438

http://dx.doi.org/10.30699/ijp.2021.138493.2512

Abstract
  Background & Objective: Differential diagnosis between cholangiocarcinoma (CCA) and metastatic pancreatic ductal adenocarcinoma (PDA) in the liver is difficult and so far, no specific immunohistochemical marker is reported to differentiate these two tumors. Considering the existing literature, the ...  Read More

GI, Liver & Pancreas Pathology
8. The Outcome of Induction Chemotherapy, Followed by Neoadjuvant Chemoradiotherapy and Surgery, in Locally Advanced Rectal Cancer

Ali Yaghobi Joybari; Behnaz Behzadi; Payam Azadeh; Sam Alahyari

Volume 16, Issue 3 , July 2021, , Pages 266-273

http://dx.doi.org/10.30699/ijp.2021.130482.2441

Abstract
  Background & Objective: Currently, neoadjuvant chemoradiotherapy, followed by surgery, is the standard treatment for locally advanced rectal cancer. The use of induction chemotherapy for this tumor is controversial. In this study, the benefits and side effects of induction chemotherapy in locally ...  Read More

GI, Liver & Pancreas Pathology
9. Microsatellite Instability and Colorectal Cancer, Immunohistochemical and Molecular Evaluation by Using DNA Sequencing: A Single Center Experience

Bita Geramizadeh; Farzaneh Bozorg-Ghalati; Firoozeh Jafari; Mitra Mirzai; Zahra Jowkar

Volume 16, Issue 3 , July 2021, , Pages 325-331

http://dx.doi.org/10.30699/ijp.2021.135222.2481

Abstract
  Background & Objective: Microsatellite instability is common in familial colorectal cancers. It can be tested by the molecular and immunohistochemical methods. There are very few studies which address comparing the clinicopathological characteristics of microsatellite stable (MSS) and microsatellite ...  Read More

GI, Liver & Pancreas Pathology
10. Candidate Molecular Biomarkers for the Non- Invasive Detection of Colorectal Cancer using Gene Expression Profiling

Mohammad Shafiei; Mahdi Alemrajabi; Ali Najafi; Amirhomayoon Keihan; Masoudreza Sohrabi

Volume 16, Issue 2 , April 2021, , Pages 203-212

http://dx.doi.org/10.30699/ijp.2021.132385.2475

Abstract
  Background and Objective: Colorectal Cancer (CRC) is the third most common cancer after prostate (breast in women) and lung cancer; it is also the third cause of cancer deaths reported in both men and women in 2020. Currently, the most commonly used diagnostic tools for CRC are colonoscopy, serological ...  Read More

GI, Liver & Pancreas Pathology
11. Clinicopathological Significance of Tumor Stem Cell Markers ALDH1 and CD133 in Colorectal Carcinoma

maryam Rezaee; Elmira Gheytanchi; Zahra Madjd; Mitra Mehrazma

Volume 16, Issue 1 , January 2021, , Pages 40-50

http://dx.doi.org/10.30699/ijp.2020.127441.2389

Abstract
  Background & Objective: Colorectal cancer (CRC) is the third most common cancer worldwide with a high mortality rate. The main causes of death in patients are recurrence and metastasis which are mainly attributed to the small subpopulation of cells within tumors called cancer stem cells (CSCs). This ...  Read More

GI, Liver & Pancreas Pathology
12. Assessment of p16 and Ki67 Immunohistochemistry Expression in Squamous Intraepithelial Lesion with Cytohistomorphological Correlation

Apurv Ghosh; M Nirupama; Nandan Padmanabha; Hema Kini

Volume 15, Issue 4 , October 2020, , Pages 268-273

http://dx.doi.org/10.30699/ijp.2020.112421.2208

Abstract
  Background & Objective: Cervical cancer is the most common cancer in women worldwide with high mortality, necessitating quicker diagnostic methods. We wish to enhance the existing cervical biopsies of Squamous Intraepithelial Lesions (SIL) using p16 and Ki67 as surrogate markers to assess correlation ...  Read More

GI, Liver & Pancreas Pathology
13. Orthotopic Liver Transplantation for Etanercept-Induced Acute Hepatic Failure; a case report

Dorsay Sadeghian; Farid Azmoudeh-Ardalan; Simin Dashti-Khavidaki; Nasir Fakhar

Volume 15, Issue 4 , October 2020, , Pages 338-341

http://dx.doi.org/10.30699/ijp.2020.117000.2269

Abstract
  The occurrence of hepatotoxicity following etanercept (tumor necrosis factor-alpha antagonist) prescription, has been studied well. However, an acute hepatic failure leading to liver transplant as an adverse effect of this drug has not been reported in the literature. In this article, we are going to ...  Read More

GI, Liver & Pancreas Pathology
14. Interobserver Agreement in Assessing Dysplasia in Colorectal Adenomatous Polyps: A Multicentric Iranian Study

Tahmineh Mollasharifi; Mahsa Ahadi; Elena Jamali; Afshin Moradi; Parisa Asghari; Saman Maroufizadeh; Behrang Kazeminezhad

Volume 15, Issue 3 , July 2020, , Pages 167-174

http://dx.doi.org/10.30699/ijp.2020.115021.2250

Abstract
  Background & Objective: Most colorectal cancers (CRCs) arise from adenomatous polyps, and clinical management of this type of polyp is highly dependent on the reliability and validity of the pathological diagnosis. The aim of this study was to examine the interobserver agreement of five pathologists ...  Read More

GI, Liver & Pancreas Pathology
15. Histopathological Evaluation and Analysis of Immunohistochemical Expression of Bcl-2 Oncoprotein in Colorectal Carcinoma

Shilpa Tukaram Patil; Clement Wilfred Devadass; Prasanna Shetty Badila

Volume 14, Issue 4 , October 2019, , Pages 317-321

http://dx.doi.org/10.30699/ijp.2019.102982.2028

Abstract
  Background & Objective: Colorectal cancer is the third most prevalent malignancy with high mortality rate, necessitating markers that predict survival and guide the treatment. Previous studies have examined the immunohistochemical expression of Bcl-2, an apoptotic marker, in colorectal carcinoma, ...  Read More

GI, Liver & Pancreas Pathology
16. Inter-observer Variability in Histomorphological Evaluation of Non-neoplastic Liver Biopsy Tissue and Impact of Clinical Information on Final Diagnosis in Shahid Beheshti University of Medical Sciences Affiliated Hospitals

Zeinab Kishani farahani; Mahsa Ahadi; Behrang Kazeminejad; Tahmineh Mollasharifi; Malihe Saber Afsharian; Amir Sadeghi; Farahnaz Bidari zerehpoosh; Elena Jamali; Niki Hasanzadeh; Abolfazl Movafagh; Arash Dehghan; Arsham Moradi; Afshin Moradi

Volume 14, Issue 3 , August 2019, , Pages 243-251

http://dx.doi.org/10.30699/ijp.2019.99566.1985

Abstract
  Background & Objective: Liver biopsy is the main method for grading and staging liver disorders, but the effects of clinical information and optimal biopsy specimen size on interpretation remain contentious. The aim of the study was to evaluate the impact of clinical information and quality of liver ...  Read More

GI, Liver & Pancreas Pathology
17. Heterotopic Pancreas as a Leading Point of Intussusception: A Case Report

Hiva Saffar; Seyed Mohammad Tavangar; Salma Sefidbakht; Roghayeh Aghapour; Fatemeh Molavi

Volume 14, Issue 2 , April 2019, , Pages 180-183

http://dx.doi.org/10.30699/ijp.14.2.180

Abstract
  Heterotopic pancreas (HP) is generally asymptomatic and found incidentally. It can act very rarely as a leading point for intussusception. Thus, it should be considered as a differential diagnosis of the mass lesions leading to the intestinal intussusception. Herein, we report an unusual case of HP as ...  Read More

GI, Liver & Pancreas Pathology
18. The Correlation between Serum Zinc Level and Liver Histology in Non-Alcoholic Steatohepatitis

Farid Kosari; Raika Jamali; Tayeb Ramim; Ebrahim Musavi Jahan Abad

Volume 14, Issue 1 , January 2019, , Pages 17-25

http://dx.doi.org/10.30699/ijp.14.1.17

Abstract
  Background & Objective: The aim of this present study was to assess the relationship between serum zinc levels and liver histopathological findings in non-alcoholic steatohepatitis (NASH) patients.Methods: This case-control study was performed in consecutively selected NASH patients who had been ...  Read More

GI, Liver & Pancreas Pathology
19. False Negative Fecal Occult Blood Test: Prozone Effect

Pathoom Sukkaromdee; Viroj Wiwanitkit

Volume 14, Issue 1 , January 2019, , Pages 94-94

http://dx.doi.org/10.30699/ijp.14.1.94

Abstract
  Dear editor, the fecal occult blood test is the presently widely used screening laboratory test for colorectal cancer. At present, the test is usually based on an immunological diagnostic principle (1, 2). A false positive fecal occult blood is common and widely mentioned in literature. Nevertheless, ...  Read More

GI, Liver & Pancreas Pathology
20. Nosocomial Jejunal Mucormycosis - an Unusual Cause of Perforation Peritonitis

Chandan Kumar; Pragya Jain; Neelam Wadhwa; Preeti Diwaker; Nirupma Khan

Volume 12, Issue 3 , July 2017, , Pages 295-300

http://dx.doi.org/10.30699/ijp.2017.25840

Abstract
  Mucormycosis is a rare but highly invasive opportunistic fungal infection. Gastrointestinal disease although uncommon is highly fatal. We report a case of jejunal mucormycosis in a 24 year old undernourished female with preceding surgical intervention for acute intestinal obstruction of tubercular etiology. ...  Read More

GI, Liver & Pancreas Pathology
21. Clinical Manifestations and Diagnosis of Non-Alcoholic Fatty Liver Disease

Mahmoodreza Khoonsari; Mohammadreza Mohammad Hosseini Azar; Ramak Ghavam; Khadijeh Hatami; Mosa Asobar; Ali Gholami; Abdolhalim Rajabi; Fahimeh Safarnezhad Tameshkel; Bahare Amirkalali; Masoudreza Sohrabi

Volume 12, Issue 2 , April 2017, , Pages 99-105

http://dx.doi.org/10.30699/ijp.2017.25038

Abstract
  Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic ...  Read More