Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Number of Volumes 16
Number of Issues 65
Number of Articles 837
Number of Contributors 2,643
View Per Article 1523.14
PDF Download Per Article 878.07
Number of Submissions 1,785
Number of Indexing Databases 49
Number of Reviewers 600
 

Iranian Journal of Pathology (Iran J Pathol)

Quarterly Journal of Anatomical and Clinical Pathology

The IRANIAN JOURNAL OF PATHOLOGY (IJP),  is an Open Access journal and publishes original research papers, reviews, case reports, short communications, and letters to the editor with priority for high-quality original papers on mechanisms of disease and clinical trials. We accept manuscripts that report important findings on disease pathogenesis and basic biological mechanisms that relate to disease without preferences for a  specific method of analysis. High priority is given to studies on human diseases and relevant experimental models that use cellular, molecular, biochemical & immunological approaches in conjunction with morphology, and to manuscripts that report new diagnostic methods or analytical systems and their application in studies of disease pathogenesis and diagnosis.   

 

  • Bone and Soft Tissue Pathology,
  • Dermatopathology,
  • Biochemistry,
  • Biology & Genetic,
  • Infectious Diseases,
  • Microbiology,
  • GI pathology & Hepatopathology,
  • Endocrine Pathology,
  • ENT & Ophthalmic Pathology,
  • Gynecologic & Breast Pathology,
  • Molecular Pathology,
  • Nephropathology,
  • Neuropathology,
  • Neuroscience and Anatomy,
  • Oncology & Hematology,
  • Oral Pathology,
  • Pediatric Pathology,
  • Surgical Pathology,
  • Diagnostic Pathology,
  • Uropathology

 

                     Publons  

 

Original Research Cytology
1. Histopathological Findings of Testicular Tissue Following Cadmium Toxicity in Rats

Saeedeh Shojaeepour; Shahriar Dabiri; Bahram Dabiri; Masoud Imani; Maryam Fekri Soofi Abadi; Fatemeh Hashemi

Volume 16, Issue 4 , Summer 2021, Pages 348-353

http://dx.doi.org/10.30699/ijp.2021.130581.2443

Abstract
  Background & Objective: Reproductive toxicity of cadmium (Cd) as an environmental toxicant has been proved in animals and humans. Exposure to Cd impairs testes organs and can reduce male fertility. The present study was designed to investigate the spectrum of histopathological changes in testicular ...  Read More

Original Research Head and Neck Pathology
2. Immunohistochemical Expression of Epithelial Mesenchymal Transition Proteins in Squamous Cell Carcinoma of the Oral Cavity

Hamideh Kadeh; Shirin Saravani; Ebrahim Miri-Moghadam

Volume 16, Issue 4 , Summer 2021, Pages 354-361

http://dx.doi.org/10.30699/ijp.2021.137498.2502

Abstract
  Background & Objective: Epithelial-Mesenchymal transition (EMT) is known to be a possible mechanism in tumor progression; however, there is insufficient evidence to support the contribution of this process in human cancers. The present study aimed to evaluate the expression of EMT markers in normal ...  Read More

Original Research Uropathology
3. Significance of Vascular Endothelial Growth Factor Expression in the Bladder Urothelial Carcinoma and Its Association with Tumor Grade and Invasiveness

Anika Sadaf; Zillur Rahman; Pradip Bhattacharjee; M. Shahab Uddin Ahamad; Sayeeda Nasreen

Volume 16, Issue 4 , Summer 2021, Pages 362-369

http://dx.doi.org/10.30699/ijp.2021.138671.2518

Abstract
  Background & Objective: Vascular Endothelial Growth Factor (VEGF) is one of the newer molecular markers that acts as a central mediator of tumor angiogenesis and is essential for tumor growth, progression, and metastasis. So anti-angiogenic drugs can be used as anticancer therapy. Treatments with ...  Read More

Original Research Dermatopathology
4. BRAF Mutation Analysis in Primary Acral Melanoma of 41 Cases from South of Iran

Fatemeh Sari Aslani; Akbar Safaee; Mozhgan Akbarzadeh Jahromi; Leila Karami

Volume 16, Issue 4 , Summer 2021, Pages 370-375

http://dx.doi.org/10.30699/ijp.2021.139458.2523

Abstract
  Background & Objective: Acral melanoma (AM) is a common type of cutaneous melanoma that occurs in the skin of the palms, soles, and nail beds. This malignancy, like other types of cancer, has different genetic alterations. To date, despite decades of research the roles of oncogenic BRAF mutations ...  Read More

Original Research Breast Pathology
5. MiRNA-218 Is Frequently Downregulated in Malignant Breast Tumors: A Footprint of Epstein-Barr Virus Infection

Javad Charostad; Mohsen Nakhaie; Azarakhsh Azaran; Gholam Abbas Kaydani; Akram Astani; Azim Motamedfar; Manoochehr Makvandi

Volume 16, Issue 4 , Summer 2021, Pages 376-385

http://dx.doi.org/10.30699/ijp.2021.521107.2550

Abstract
  Background & Objective: The role of Epstein-Barr Virus in development of breast cancer is frequently studied. In this regard, miRNAs are among the contributing elements in the molecular pathophysiology of EBV-related diseases. In addition, a growing number of host miRNAs are believed to be implicated ...  Read More

Original Research Microbiology
6. Molecular Characterization of Antibiotic Resistance Associated with TEM and CTX-M ESBL in Uropathogenic E. coli Strains Isolated from Outpatients

Sorour Farzi; Reza Ranjbar; Mohammad Niakan; Mohammad Hossein Ahmadi

Volume 16, Issue 4 , Summer 2021, Pages 386-391

http://dx.doi.org/10.30699/ijp.2021.521669.2556

Abstract
  Background & Objective: Escherichia coli (E. coli) is a leading cause of urinary tract infections becoming resistant against beta-lactams and cephalosporins through different mechanisms, including ESBL production due to the presence of ESBL specific genes, including blaCTX-M and blaTEM. The purpose ...  Read More

Original Research Breast Pathology
7. Role of Cell Block Technology as an Adjunct to Fine Needle Aspiration in Evaluating as well as Differentiating Liver Lesions

Sujata Mallick; Mahasweta Mallik; Rabindra Nath Chatterjee; Puskar Shyam Chowdhury

Volume 16, Issue 4 , Summer 2021, Pages 392-402

http://dx.doi.org/10.30699/ijp.2021.522897.2569

Abstract
  Background & Objective: Liver lesions are difficult to diagnose and to differentiate primary from metastatic carcinoma, while Biopsy has its limitations. Cell block technology is easily accessible with high diagnostic accuracy. Our aim is 1) To find the role of cell block technology as an alternative ...  Read More

Original Research Microbiology
8. Evaluating of the Effects of Sub-MIC Concentrations of Gentamicin on Biofilm Formation in Clinical Isolates of Pseudomonas aeruginosa

Zahra Yousefpour; Fateme Davarzani; Parviz Owlia

Volume 16, Issue 4 , Summer 2021, Pages 403-410

http://dx.doi.org/10.30699/ijp.2021.524220.2584

Abstract
  Background & Objective: The ability of Pseudomonas aeruginosa to form biofilm has an important role in establishment of chronic phase of infections. Biofilm formation can be affected by antibiotics sub-MIC concentrations. The principal aim of the present study was to evaluate the effect of gentamicin ...  Read More

Original Research Uropathology
9. Evaluation of ERG Expression in Prostate Adenocarcinoma and Its Prognostic Impact in Patients Survival Rate

Hedieh Moradi Tabriz; Leila Aghapour Sabaghi; Amirreza Nabighadim; Elham Nazar; Seyed Mohammad Kazem Aghamir

Volume 16, Issue 4 , Summer 2021, Pages 411-417

http://dx.doi.org/10.30699/ijp.2021.530515.2644

Abstract
  Background & Objective: Some certain markers, including prostatic specific antigen (PSA), are being used to screen prostate cancer (PC), but none of them have sufficient sensitivity and specificity for evaluation of prognosis. Currently, genetic variants have found their place in the prognosis of ...  Read More

Original Research Cytology
10. Cytogenetic Studies of 608 couples with Recurrent Spontaneous Abortions in Northeastern Iran

Narjes Soltani; Farzaneh Mirzaei; Hossein Ayatollahi

Volume 16, Issue 4 , Summer 2021, Pages 418-425

http://dx.doi.org/10.30699/ijp.2021.521514.2554

Abstract
  Background & Objective: One of the major genetic causes of recurrent spontaneous abortions is parental chromosomal abnormalities. The objectives of the study were to determine, compare and analyze the incidence and distribution of chromosomal abnormalities in couples with recurrent miscarriages from ...  Read More

Original Research Microbiology
11. The role of Gene Mutations (gyrA, parC) in Resistance to Ciprofloxacin in Clinical Isolates of Pseudomonas Aeruginosa

Zoheir Heshmatipour; Nasibeh Arabameri; Shima Eftekhar Ardebili; Zeinab Jafari Bidhendi

Volume 16, Issue 4 , Summer 2021, Pages 426-432

http://dx.doi.org/10.30699/ijp.2021.520570.2542

Abstract
  Background & Objective: Pseudomonas aeruginosa is an opportunistic pathogen and one of the most common causes of nosocomial infections. This bacterium's antibiotic resistance to the common fluoroquinolone antibiotics, especially ciprofloxacin, is due to mutations in the gyrA and parC genes. This ...  Read More

Short Communication GI, Liver & Pancreas Pathology
12. Annexin Expression in Cholangiocarcinoma, and Metastatic Pancreatic Ductal Adenocarcinoma “Is it be Helpful for Differential Diagnosis of These Tumors in the Liver?”

Bita Geramizadeh; Mahsa Sehat; Azam Mehrmozayan; Alireza Shojazadeh

Volume 16, Issue 4 , Summer 2021, Pages 433-438

http://dx.doi.org/10.30699/ijp.2021.138493.2512

Abstract
  Background & Objective: Differential diagnosis between cholangiocarcinoma (CCA) and metastatic pancreatic ductal adenocarcinoma (PDA) in the liver is difficult and so far, no specific immunohistochemical marker is reported to differentiate these two tumors. Considering the existing literature, the ...  Read More

Short Communication Microbiology
13. COVID-19 Impact on Modern Virtual Pathology Education: Challenges and Opportunities

Seyed Esmaeil Azimi Khatibani; Shima Tabatabai

Volume 16, Issue 4 , Summer 2021, Pages 439-443

http://dx.doi.org/10.30699/ijp.2021.525144.2589

Abstract
  Background & Objective: Pathology education conventional methods have been disrupted by the Corona-Virus Disease 2019 (COVID-19) outbreak, compelling a re-evaluation of the means of educational interactions from the undergraduate to the postgraduate level. This commentary explores how the COVID-19 ...  Read More

Short Communication Molecular Pathology
14. MIF and MMP-9 Serum Changes in Type II Diabetes and Non-Diabetic Subjects: A Short Communication

Alireza Rastgoo Haghi; Nasrin Khorami; Mahtab Fotoohi; Abbas Moradi

Volume 16, Issue 4 , Summer 2021, Pages 444-447

http://dx.doi.org/10.30699/ijp.2021.131429.2456

Abstract
  Background & Objective: Diabetes is a metabolic disease and is associated with failure of various organs. Macrophage migration factor (MIF) and matrix metalloproteinase (MMP-9) are two of the most important factors in the pathogenesis of diabetes.Methods: In this descriptive-analytical study, 30 ...  Read More

Case Reports Cardiovascular Pathology
15. Primary Pericardial Epithelioid Angiosarcoma: A Diagnostic Dilemma: A Case Report

Tahmineh Mollasharifi; Behrang Kazeminezhad

Volume 16, Issue 4 , Summer 2021, Pages 448-450

http://dx.doi.org/10.30699/ijp.2021.136440.2494

Abstract
  The incidence of pericardial epithelioid angiosarcoma is rare. Angiosarcoma of pericardium may coat the pericardium in a diffuse fashion. Diagnosis of an angiosarcoma is challenging and may be easily mistaken as constrictive pericarditis. Herein, a case of primary pericardial angiosarcoma is reported ...  Read More

Case Reports Breast Pathology
16. Myofibroblastoma of the Breast: A Morphologic and Immunohistochemical Study of Three Cases

Hiva Saffar; Dorna Motevalli; Nasibeh Seirfar; Mahsa Ebrahimi; Perikala Vijayananda Kumar; Farid Kosari; Hedieh Moradi Tabriz; Sadaf Naderi; Golsa Shekarkhar

Volume 16, Issue 4 , Summer 2021, Pages 451-455

http://dx.doi.org/10.30699/ijp.2021.138647.2520

Abstract
  Myofibroblastoma (MFB) of the breast is an uncommon entity of benign spindle neoplasms of the breast. This tumour possesses a broad spectrum of histomorphological patterns. Distinguishing of myofibroblastoma variants from malignant mimics of this benign neoplasm is essential for pathologists to avoid ...  Read More

Case Reports Gynecologic Pathology
17. An Unusual Presentation of Giant Fibroepithelial Polyp of the Vagina

Azar Daneshpajooh; Mahboubeh Mirzaei; Maryam Iranpour

Volume 16, Issue 4 , Summer 2021, Pages 456-460

http://dx.doi.org/10.30699/ijp.2021.522689.2566

Abstract
  Fibroepithelial polyps of the vagina (FEPV) are rare entities which normally manifest as one or more painless polyps sometimes with symptoms such as bleeding, vaginal discharge, and discomfort regarding the size of the mass. Despite their benign nature, they can be confused with other vaginal tumors ...  Read More

Case Reports Uropathology
18. Primary Testis Leiomyosarcoma: A Case Report

Elham Nazar; Zohre Shabanzadeh; Amir Ahmadi; Niloofar Rostami

Volume 16, Issue 4 , Summer 2021, Pages 461-464

http://dx.doi.org/10.30699/ijp.2021.524644.2586

Abstract
  Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develop  after radiotherapy or long term taking anabolic steroid medication . We report a  53-year-old male patient with primary testis leiomyosarcoma  who presented with painless testicular  enlargement ...  Read More

Letters to the Editor Gynecologic Pathology
19. Chemotherapeutic Effect on Ovarian Stroma and Tumor Cells Which Make Problem in Diagnosis and Staging of Tumor

Neda Nasirian; Khadigeh Elmizadeh

Volume 16, Issue 4 , Summer 2021, Pages 465-466

http://dx.doi.org/10.30699/ijp.2021.520513.2540

Abstract
  Chemotherapy of ovarian tumors has some effects on morphology of stromal cells also residual tumoral cells which can cause problems in diagnosis of tumor type and staging of it .In some cases ,it can makes problem in diagnosis of residual epithelial tumor from other differential diagnosis such as spindle ...  Read More

Molecular Pathology
1. Pre-analytical Practices in the Molecular Diagnostic Tests, A Concise Review

Maryam Sotoudeh Anvari; Atoosa Gharib; Maryam Abolhasani; Aileen Azari-Yaam; Farzaneh Hossieni Gharalari; Moeinadin Safavi; Ali Zare-Mirzaie; Mohammad Vasei

Volume 16, Issue 1 , Winter 2021, , Pages 1-19

http://dx.doi.org/10.30699/ijp.2020.124315.2357

Abstract
  Molecular assays for detection of nucleic acids in biologic specimens are valuable diagnostic tools supporting clinical diagnoses and therapeutic decisions. Pre-analytical errors, which occur before or during processing of nucleic acid extraction, contribute a significant role in common errors which ...  Read More

Head and Neck Pathology
2. The Frequency of Human Papillomavirus Positivity in Iranian Patients with Head and Neck Squamous Cell Carcinoma

Mitra Rezaei; Mahboobeh Karimi-Galougahi; Azin Kheradmand; Mihan Pourabdollah Toutkaboni; Hassan Mir Mohammad Sadeghi; Alireza Abdollahi; Amirnader Emami Razavi; Ali Safavi Naini; Farahnaz Bidari- Zerehpoosh

Volume 16, Issue 1 , Winter 2021, , Pages 20-26

http://dx.doi.org/10.30699/ijp.2020.119344.2300

Abstract
  Background & Objective: Human papillomavirus (HPV) has been associated with prognosis in patients with head and neck squamous cell carcinoma (HNSCC). Similar to the global studies, different prevalence rates of this viral infection have been reported in Iran. Therefore, we aimed to report the prevalence ...  Read More

Molecular Pathology
3. Variants of Genes Involved in Metabolism of Folate among Patients with Breast Cancer: Association of TYMS 3R Allele with Susceptibility to Breast Cancer and Metastasis

Zohreh Rahimi; Maryam Bozorgi Zarini Bozorgi Zarini; Ziba Rahimi; Ebrahim Shakiba; Asad Vaisi-Raygani; Mohammad Taher Moradi; Kheirolah Yari

Volume 16, Issue 1 , Winter 2021, , Pages 62-68

http://dx.doi.org/10.30699/ijp.2020.117676.2283

Abstract
  Background & Objective: Breast cancer (BC) is known to be the most prevalent cancer among women. One-carbon metabolism (OCM) disturbance might play an important role in the etiology of BC. The present study aimed to investigate the thymidylate synthase (TYMS), 5-methyltetrahydrofolate-homocysteine ...  Read More

Dermatopathology
4. Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report

Fatmagul Kusku; Damlanur Sakiz

Volume 16, Issue 1 , Winter 2021, , Pages 79-83

http://dx.doi.org/10.30699/ijp.2020.128904.2408

Abstract
  Coronavirus is a single-stranded RNA virus that causes acute respiratory syndrome and various skin lesions. In addition, ischemic acral lesions have been reported in patients with severe coronavirus disease 2019 (COVID-19) due to coagulation disorders. We here present a case with ischemic acral lesions ...  Read More

GI, Liver & Pancreas Pathology
5. Clinicopathological Significance of Tumor Stem Cell Markers ALDH1 and CD133 in Colorectal Carcinoma

maryam Rezaee; Elmira Gheytanchi; Zahra Madjd; Mitra Mehrazma

Volume 16, Issue 1 , Winter 2021, , Pages 40-50

http://dx.doi.org/10.30699/ijp.2020.127441.2389

Abstract
  Background & Objective: Colorectal cancer (CRC) is the third most common cancer worldwide with a high mortality rate. The main causes of death in patients are recurrence and metastasis which are mainly attributed to the small subpopulation of cells within tumors called cancer stem cells (CSCs). This ...  Read More

Original Research Uropathology
1. The Expression of Autophagy Markers Beclin1 and LC3B in Prostatic Carcinoma: Immunohistochemical Case-Control Study

Nanis Shawky Holah; Marwa Mohammed Serag El-Dien; Shereen Fathy Mahmoud

Articles in Press, Accepted Manuscript, Available Online from 03 October 2021

http://dx.doi.org/10.30699/ijp.2021.530887.2649

Abstract
  Background and Objective: Prostatic carcinoma represents the second most common cancer diagnosed in men worldwide after lung cancer and the fourth common male malignancy in Egypt. Autophagy is a natural process that has both oncogenic and tumor-suppressive activities. This study aims to evaluate the ...  Read More

Case Reports Head and Neck Pathology
2. Synchronous Occurrence of Papillary Thyroid Carcinoma and Medullary Carcinoma in Hashimoto’s Thyroiditis and Multi Nodular Goiter Background

Fatemeh Samiee Rad; Ali Emami

Articles in Press, Accepted Manuscript, Available Online from 20 October 2021

http://dx.doi.org/10.30699/ijp.2021.527288.2606

Abstract
  Background & Objective: Coexistence of follicular epithelial and bilateral parafollicular cells derivative of carcinomas in Hashimoto’s thyroiditis and multinodular goiter background are a very rare event. Of course, all benign and malignant thyroid lesions are more prevalent in iodine deficient ...  Read More

Case Reports Oral Pathology
3. A Rare Case of Brain Metastasis from dedifferentiated Acinic Cell Carcinoma of Parotid Gland and Review of the Literature

Elham Mirzaian; Shafighe Asgarikarchekani; Ashkan Abdoli

Articles in Press, Accepted Manuscript, Available Online from 20 August 2021

http://dx.doi.org/10.30699/ijp.2021.530574.2645

Abstract
  Acinic cell carcinoma (ACC) is a low or intermediate-grade malignant epithelial neoplasm of the salivary glands that generally shows an indolent behavior. Most cases arise in the major salivary glands, especially the parotid gland. ACC is usually known as a low-grade malignant tumor; however, poorly ...  Read More

Letters to the Editor Oral Pathology
4. The Odontogenic Keratocyst Conundrum- Is There an Answer?

Sabarinath B; Protyusha GB; Dhanarathna S; Kaushik Prakash

Articles in Press, Accepted Manuscript, Available Online from 09 August 2021

http://dx.doi.org/10.30699/ijp.2021.529691.2636

Abstract
  Odontogenic keratocyst (OKC) is a unique developmental odontogenic cyst which seem to be controversy’s favourite child since the time of its inception. This lesion has garnered special attention over the last two decades owing to the increasing confusion over its nomenclature and classification. ...  Read More

Original Research Microbiology
5. The Performance of SARS-CoV-2 Serology Testing in the Diagnosis of COVID-19

Alireza Abdollahi; Samaneh Salarvand; Vahid Mehrtash; Bita Jafarzadeh; Mohammadreza Salehi; Reza Ghalehtaki; Saeed Nateghi

Articles in Press, Accepted Manuscript, Available Online from 05 August 2021

http://dx.doi.org/10.30699/ijp.2021.526032.2597

Abstract
  Background & Objective: COVID-19 reverse transcription-polymerase chain reaction (RT-PCR) has been a reference test for diagnosing a disease since the very beginning of the pandemic. COVID-19 serology tests have also been developed and used to estimate the prevalence of individuals who have already ...  Read More

Original Research Microbiology
6. Is There A Correlation Between COVID-19 and Hepatitis A and Hepatitis E Serum Antibody Level?

Alireza Abdollahi; Samaneh Salarvand; Vahid Mehrtash; Bita Jafarzadeh; Reza Ghalehtaki; Saeed Nateghi

Articles in Press, Accepted Manuscript, Available Online from 03 August 2021

http://dx.doi.org/10.30699/ijp.2021.528077.2615

Abstract
  Background & Objective: The prevalence of COVID-19 and its severity have been observed to be on a lower level in underdeveloped countries with poorer standards of hygiene. This disparity may be attributed to the higher seroprevalence of other viral diseases which can result in the presence of antibodies ...  Read More

Original Research Cytology
7. Direct Smear Versus Liquid-Based Cytology in the Diagnosis of Bladder Lesions

Mahmoud Reza Kalantari; Mohammad Ali Jahanshahi; Masoumeh Gharib; Sara Hashemi; Shakiba Kalantari

Articles in Press, Accepted Manuscript, Available Online from 15 November 2021

http://dx.doi.org/10.30699/ijp.2021.528171.2646

Abstract
  Background & Objective: Urine cytology is an important diagnostic method for urinary tract cancers (especially carcinomas), which is suitable for follow-up of residual urothelial tumors after surgery of malignant bladder tumors. In this study, for the first time, liquid-based cytology (LBC) was used ...  Read More

Case Reports GI, Liver & Pancreas Pathology
8. Intestinal Infarction in COVID-19 Pandemic: A Case Series

maryam Sarkardeh; Amin Dalili; Naser T Tayyebi Meibodi; Mostafa Izanlu; Seyed Javad Davari-Sani; Saeed Moghaddamzade; Mehdi Jamalinik; Seyed Javad Hosseini; Javad Koushki; Ali Abedia

Articles in Press, Accepted Manuscript, Available Online from 07 November 2021

http://dx.doi.org/10.30699/ijp.2021.525280.2600

Abstract
  Novel coronavirus disease 2019 (COVID-19) as a potential health risk factor continues to spread throughout the world. Although common symptoms include headache and respiratory symptoms, some studies have suggested that COVID-19 may cause coagulation disorders and thrombolytic events, disrupt blood flow ...  Read More

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Iranian Journal of Pathology

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