Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Number of Volumes 17
Number of Issues 67
Number of Articles 863
Number of Contributors 2,749
View Per Article 1561.02
PDF Download Per Article 893.46
Number of Submissions 1,925
Number of Indexing Databases 49
Number of Reviewers 653
 

Iranian Journal of Pathology (Iran J Pathol)

Quarterly Journal of Anatomical and Clinical Pathology

The IRANIAN JOURNAL OF PATHOLOGY (IJP),  is an Open Access journal and publishes original research papers, reviews, case reports, short communications, and letters to the editor with priority for high-quality original papers on mechanisms of disease and clinical trials. We accept manuscripts that report important findings on disease pathogenesis and basic biological mechanisms that relate to disease without preferences for a  specific method of analysis. High priority is given to studies on human diseases and relevant experimental models that use cellular, molecular, biochemical & immunological approaches in conjunction with morphology, and to manuscripts that report new diagnostic methods or analytical systems and their application in studies of disease pathogenesis and diagnosis.   

 

  • Bone and Soft Tissue Pathology,
  • Dermatopathology,
  • Biochemistry,
  • Biology & Genetic,
  • Infectious Diseases,
  • Microbiology,
  • GI pathology & Hepatopathology,
  • Endocrine Pathology,
  • ENT & Ophthalmic Pathology,
  • Gynecologic & Breast Pathology,
  • Molecular Pathology,
  • Nephropathology,
  • Neuropathology,
  • Neuroscience and Anatomy,
  • Oncology & Hematology,
  • Oral Pathology,
  • Pediatric Pathology,
  • Surgical Pathology,
  • Diagnostic Pathology,
  • Uropathology

 

                     Publons  

 

Systematic Review Microbiology
The Epidemiological, Clinical, Mycological, and Pathological Features of Rhino-cerebral Mucormycosis: A Systematic Review

Mohammadreza Salehi; Shahram Mahmoudi; Omid Rezahosseini; Sayed Jamal Hashemi; Kazem Ahmadikia; Farzad Aala; Nasim Khajavirad; Neda Alijani; Alireza Izadi; Muhammad Ibrahim Getso; Alireza Abdollahi; Arezoo Salami; Seyedeh Rana Khatami; Alireza Adibimehr; Mojtaba Hedayat Yaghoobi; Mohammadmahdi Sabahi; Behshad Pazooki; Farhad Yazdi; Jayran Zebardast; Arash Seifi; Malihe Hasan Nezhad; Masoud Mardani; Sadegh Khodavaisy

Volume 17, Issue 2 , April 2022, Pages 112-121

http://dx.doi.org/10.30699/ijp.2022.538690.2721

Abstract
  Cerebral mucormycosis (CM) is a life-threatening manifestation of mucormycosis, an angioinvasive fungal infection caused by Mucorales. We sought to systematically review all available case reports to describe epidemiologic features, clinical manifestations, predisposing factors, and diagnostic and treatment ...  Read More

Review Article Neuropathology
The Role of Micro RNAs in Regulating PI3K/AKT Signaling Pathways in Glioblastoma

Roshanak Ghaffarian Zirak; Hurie Tajik; Jahanbakhsh Asadi; Pedram Hashemian; Hossein Javid

Volume 17, Issue 2 , April 2022, Pages 122-136

http://dx.doi.org/10.30699/ijp.2022.539029.2726

Abstract
  Glioblastoma is a type of brain cancer with aggressive and invasive nature. Such features result from increased proliferation and migration and also poor apoptosis of glioma cells leading to resistance to current treatments such as chemotherapy and radiotherapy. In recent studies, micro RNAs have been ...  Read More

Original Research Endocrine Pathology
Quantity and Distribution of Eosinophils in Esophageal Specimens of Adults: An Iranian Population-Based Study

Elena Jamali; Behrang Kazeminezhad; Mahsa Ahadi; Afshin Moradi; Hamideh Khabbazi

Volume 17, Issue 2 , April 2022, Pages 136-142

http://dx.doi.org/10.30699/ijp.2021.520951.2546

Abstract
  Background & Objective: Eosinophils are normally found in different parts of the gastrointestinal tract and with less prevalence in the esophagus. Eosinophilic infiltration is increased as part of inflammatory reactions in various diseases. The aim of this study was to determine the count and distribution ...  Read More

Original Research GI, Liver & Pancreas Pathology
Immunohistochemical Expression of CDX2 in Gastric Carcinoma

Avan Sardar Ahmed; Jalal Ali Jalal; Kalthuma Salih Hamad Ameen

Volume 17, Issue 2 , April 2022, Pages 143-149

http://dx.doi.org/10.30699/ijp.2022.530631.2648

Abstract
  Background & Objective: Gastric cancer (GC) persists to be a major health issue globally, and the need to investigate new molecular markers for improving the survival of patients continues. CDX2 is a homeobox caudal protein family member encoded by the CDX2 gene and is probably playing a role in ...  Read More

Original Research GI, Liver & Pancreas Pathology
Clinicopathological Significance of PTEN Expression and Its Prognostic Effect in Colorectal Adenocarcinoma Patients

Zohreh Mirzapour Abbas abadi; Fatemeh Samiee Rad; Dariush Hamedi Asl; Babak Rahmani; Mahmood Soleimani Dodaran; Amir Peimani

Volume 17, Issue 2 , April 2022, Pages 150-158

http://dx.doi.org/10.30699/ijp.2021.531779.2653

Abstract
  Background & Objective: Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene located at chromosome 10. PTEN is a regulator of the PI3K/AKT signaling pathway that inhibits cell proliferation and promotes apoptosis. PTEN loss of function occurs in a spectrum  of cancers, including ...  Read More

Original Research Pulmonary Pathology
The Frequency of Epidermal Growth Factor Receptor (EGFR) Mutation in Patients with Lung Adenocarcinoma Referred to a Lung Diseases Hospital; A Cross-Sectional Study from Iran

Sotoudeh Mohammadi; Mitra Rezaei; Fatemeh Shojaeian; Mihan Pourabdollah; Leila Mohammadi Ziazi; Sharareh Seifi; Atousa Doroodinia; Babak Salimi; Adnan Khosravi; Mohammad Amin Farhangnasab

Volume 17, Issue 2 , April 2022, Pages 159-165

http://dx.doi.org/10.30699/ijp.2022.533427.2673

Abstract
  Background & Objective: Various studies showed the use  of epidermal growth factor receptors (EGFRs) gene mutations in the therapeutic plan of patients with advanced lung cancer. This study aimed to investigate the frequency and types of EGFR gene mutations among Iranian patients with lung adenocarcinoma ...  Read More

Original Research GI, Liver & Pancreas Pathology
Quantity and Distribution of Eosinophils in the Adult Human Gastric Specimens

Behrang Kazeminezhad; Helia Falahatian Mehrjardi; Afshin Moradi; Tahmineh Mollasharifi

Volume 17, Issue 2 , April 2022, Pages 166-173

http://dx.doi.org/10.30699/ijp.2022.537842.2706

Abstract
  Background & Objective: The existence of eosinophils in the gastric mucosal epithelium is unusual, while the term "eosinophilic gastritis" has become overused due to the increased numbers of eosinophils found in gastric specimens. Thus, we aimed to assess the number and distribution of eosinophils ...  Read More

Original Research Uropathology
Diagnostic and Therapeutic Implications of Sortilin Expressed on the Surface of Bladder Carcinoma Cells

Ali-Ahmad Bayat; Niloufar Sadeghi; Ghazaleh Fazli; Mohammad Reza Nowroozi; Solmaz Ohadian Moghadam; Amin Radmanesh; Mohammadjavad Hedayatshodeh; Ali Reza Sarrafzadeh; Omid Zarei; Fatemeh Ghaemimanesh; Hodjattallah Rabbani

Volume 17, Issue 2 , April 2022, Pages 174-182

http://dx.doi.org/10.30699/ijp.2022.539411.2732

Abstract
  Background & Objective: Cell surface expression of sortilin in different types of cancer signifies it as a therapeutic target for cancer therapy. The aim of this study was to detect sortilin expression in bladder cancer cells using an anti-sortilin monoclonal antibody (mAb) to evaluate sortilin as ...  Read More

Original Research Breast Pathology
Apoptosis Induction, Cell Cycle Arrest and Anti-Cancer Potential of Tamoxifen-Curcumin Loaded Niosomes Against MCF-7 Cancer Cells

Mahdi Fatemizadeh; Farzaneh Tafvizi; Farzaneh Shamsi; Sahar Amiri; Afsaneh Farajzadeh; Iman Akbarzadeh

Volume 17, Issue 2 , April 2022, Pages 183-190

http://dx.doi.org/10.30699/ijp.2022.124340.2358

Abstract
  Background & Objective: Breast cancer is the most common cancer among women. One of the most effective treatments for breast cancer is chemotherapy, in which specific drugs destroy the mass and its proliferation is inhibited. Chemotherapy is the most effective adjunctive therapy when multiple medications ...  Read More

Original Research Statistics
Scientometrics Analysis of World Scientific Research of Pathology and Forensic Medicine

Zeinab Jozi; Hamzehali Nourmohammadi

Volume 17, Issue 2 , April 2022, Pages 191-201

http://dx.doi.org/10.30699/ijp.2022.541660.2756

Abstract
  Background & Objective: This study examines the extent of scientific publications and patents in pathology and forensic medicine globally and the citation relationship between them from 2011 to 2020, indexed in the Scopus database.Methods: In this scientometric study, data were extracted from the ...  Read More

Original Research Gynecologic Pathology
Significance of Endocan Expression in Various Types of Epithelial Ovarian Tumors

Maryam Entezarian; Fereshteh Ameli; Noraidah Masir; Tan Geok Chin

Volume 17, Issue 2 , April 2022, Pages 202-209

http://dx.doi.org/10.30699/ijp.2022.540192.2740

Abstract
  Background & Objective: Ovarian cancer is associated with the highest mortality rate among gynecologic malignancies. Despite new therapeutic strategies, ovarian cancer still has a high risk of metastasis and mortality. Endocan is a newly identified endothelial cell activation marker, which is responsible ...  Read More

Original Research Oral Pathology
The Association of CCL4 rs1634507 and rs10491121 Polymorphisms with Susceptibility of Oral Squamous Cell Carcinoma in an Iranian Population: A Case-Control Study

Hamideh Kadeh; Mohammad Eini; Maliheh Parsasefat; Ebrahim Miri-Moghaddam

Volume 17, Issue 2 , April 2022, Pages 210-216

http://dx.doi.org/10.30699/ijp.2022.538948.2725

Abstract
  Background & Objective: CCL4 (C-C chemokine ligand4) is a chemoattractant involved in tumors' development, progression, and metastasis. The relationship between the ccl4 gene polymorphisms and the risk of OSCC has not been studied in Iran. This study aimed to identify the effect of ccl4 gene polymorphism ...  Read More

Original Research Breast Pathology
A Novel Subset of Triple-Negative Breast Cancers with Unique Histology and Immunohistochemical Expression

Swaminathan Kalyanasundaram; Shantaraman Kalyanaraman; Hidhaya Kaleelullah Fathima; Vidhya Mohan; Kavitha Selvaraj

Volume 17, Issue 2 , April 2022, Pages 217-224

http://dx.doi.org/10.30699/ijp.2022.139734.2526

Abstract
  Background & Objective: Triple-Negative Breast Carcinoma (TNBC) is characterized by an absence of estrogen receptor, progesterone receptor and HER2 neu expression, with distinct molecular, histological and clinical features, aggressive clinical course and a poor prognosis. The objective was to evaluate ...  Read More

Case Reports Endocrine Pathology
Papillary Thyroid Carcinoma with Nodular Fasciitis-Like Stroma in a 28-Year-Old Patient

Vahid Zand; Mansour Moghimi; Elmira Sadeghi; Pegah Kamal; Sedighe Vaziribozorg

Volume 17, Issue 2 , April 2022, Pages 225-228

http://dx.doi.org/10.30699/ijp.2022.139405.2525

Abstract
  AbstractPapillary thyroid carcinoma (PTC) is considered as a relatively common type of malignancy showing a wide morphologic spectrum. Different variants of this tumor have been reported. Among PTC variants, PTC with nodular fasciitis-like stroma (PTC‑FLS) is rare. This variant consists of stromal ...  Read More

Case Reports Gynecologic Pathology
A Case of Premenopausal Uterine Leiomyoma, Non-cirrhotic Portal Fibrosis, Hepatic Koch's, a PET Gone Astray-Morphology Antidotes a Confounding Concoction

Kavita Gaur; Shailaja Shukla; Shinjini Choudhury; Pankaj Raj; Sharda Patra

Volume 17, Issue 2 , April 2022, Pages 229-233

http://dx.doi.org/10.30699/ijp.2022.540258.2743

Abstract
  Uterine leiomyoma with hepatic vasculopathy, specifically non-cirrhotic portal fibrosis (NCPF), has hitherto been undescribed. NCPF is characterized by elevated portal pressure sans cirrhosis and has previously not been described in association with a gynecological pathology. We report the case of a ...  Read More

Case Reports Dermatopathology
Nevus Comedonicus with Epidermolytic Hyperkeratosis: A Case Report

Faezeh Taghavi; Sima Davoodi; Naser Tayyebi Meibodi; Yalda Nahidi; Mostafa Izanlu

Volume 17, Issue 2 , April 2022, Pages 234-237

http://dx.doi.org/10.30699/ijp.2022.542761.2767

Abstract
  Nevus comedonicus (NC) is a rare developmental anomaly of the folliculosebaceous apparatus, which appears as numerous dilated papules containing firm, darkly pigmented, horny plugs. It appears shortly after birth and mostly before the age of 10; however, late-onset cases have been reported. There is ...  Read More

Letters to the Editor Oral Pathology
Oral Microbiome in Head and Neck Cancers: An Insight, Are We Looking at a Step Beyond in Unraveling the Challenge?

Vaishnavi Vedam; Sivadas Ganapathy

Volume 17, Issue 2 , April 2022, Pages 238-240

http://dx.doi.org/10.30699/ijp.2022.544926.2791

Abstract
  Dear EditorHead and Neck Cancers (HNCs) contribute to one of the global health concerns and have been a challenge to oncologists for decades. Breakthroughs in research with evidence-based reports based on diagnostic and therapeutic approaches in clinical practice have been published to address patient ...  Read More

Cytology
An Investigation on the Results of Cytopathologic Tests of Pancreatobiliary System Performed in the Pathology Department in Iran

Afshin Moradi; Amir Sadeghi; Hamid Asadzadeh Aghdaei; Tahmineh Mollasharifi; Mahsa Ahadi; Elena Jamali; Afsoon Taghavi; Nasim Foroozandeh Shahraki; Arsham Moradi

Volume 16, Issue 3 , July 2021, , Pages 256-265

http://dx.doi.org/10.30699/ijp.2021.131467.2462

Abstract
  Background & Objective: Pancreatobiliary system disorders commonly include inflammatory diseases and tumors. Diagnosis of pancreatic cancer is challenging and is mostly achieved when the disease has extensively progressed, and metastasis has occurred. Therefore, this study was performed to evaluate ...  Read More

Biology & Genetic
Effects of Human Nucleolus Upon Guest Viral-Life, Focusing in COVID-19 Infection: A Mini- Review

Moslem Bahadori; Mohammad Hossein Azizi; Shahriar Dabiri; Neda Bahadori

Volume 17, Issue 1 , January 2022, , Pages 1-7

http://dx.doi.org/10.30699/ijp.2021.540305.2744

Abstract
  The nucleolus is a subcellular membraneless structure of eukaryotic cells. In 1965, in a world’s southern summer summit in Uruguay, the role of the nucleolus as the site of ribosome synthesis, biogenesis, and processing of tRNA was conclusively established. Today, accumulating evidence confirm ...  Read More

Cytology
Histopathological Findings of Testicular Tissue Following Cadmium Toxicity in Rats

Saeedeh Shojaeepour; Shahriar Dabiri; Bahram Dabiri; Masoud Imani; Maryam Fekri Soofi Abadi; Fatemeh Hashemi

Volume 16, Issue 4 , August 2021, , Pages 348-353

http://dx.doi.org/10.30699/ijp.2021.130581.2443

Abstract
  Background & Objective: Reproductive toxicity of cadmium (Cd) as an environmental toxicant has been proved in animals and humans. Exposure to Cd impairs testes organs and can reduce male fertility. The present study was designed to investigate the spectrum of histopathological changes in testicular ...  Read More

Dermatopathology
Cardiac Involvement and Subsequent Death due to Extranodal NK/T Cell Cutaneous T-Cell Lymphoma: An Autopsy Case and Brief Review of the Literature

Nikolaos D. Goutas; Emmanouil I. Sakelliadis; Eleftheria Lakiotaki; Konstantinos D. Katsos; Kalliroi Spanou; Pinelopi Korkolopoulou; Dimitrios G. Vlachodimitropoulos

Volume 16, Issue 3 , July 2021, , Pages 337-342

http://dx.doi.org/10.30699/ijp.2021.139566.2524

Abstract
  Cardiac tumors range from benign to high grade malignancies. The incidence of cardiac involvement either by primary, or secondary tumors during autopsy is reported to be extremely low. Extranodal NK/T-cell lymphoma (ENKTL), nasal type is an unusual type of lymphoma. The skin is the second most common ...  Read More

Neuropathology
The Role of Micro RNAs in Regulating PI3K/AKT Signaling Pathways in Glioblastoma

Roshanak Ghaffarian Zirak; Hurie Tajik; Jahanbakhsh Asadi; Pedram Hashemian; Hossein Javid

Volume 17, Issue 2 , April 2022, , Pages 122-136

http://dx.doi.org/10.30699/ijp.2022.539029.2726

Abstract
  Glioblastoma is a type of brain cancer with aggressive and invasive nature. Such features result from increased proliferation and migration and also poor apoptosis of glioma cells leading to resistance to current treatments such as chemotherapy and radiotherapy. In recent studies, micro RNAs have been ...  Read More

Pre-Cancerous Lesions in the Oral and Maxillofacial Region: A Literature Review with Special Focus on Etiopathogenesis

Soussan Irani

Volume 11, Issue 4 , October 2016, , Pages 303-322

Abstract
  Many types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral ...  Read More

Intra-familial Transmission of Hepatitis B Virus Infection in Arak, Central Iran

Masoomeh Sofian; Mohammad Banifazl; Masoomeh Ziai; Arezoo Aghakhani; Ali-Asghar Farazi; Amitis Ramezani

Volume 11, Issue 4 , October 2016, , Pages 328-333

Abstract
  Background: The household transmission of hepatitis B virus (HBV) is a major health problem. High incidence of HBV infection is observed within the household contacts of HBV carriers. We aimed to evaluate serological markers of hepatitis B infection among family members of HBV carriers in Arak, central ...  Read More

Oral Pathology
Expression of Human Kallikreins 4, 8, 10, 11 and 13 in Pleomorphic Adenomas and Mucoepidermoid Carcinomas

Maryam Alsadat Hashemipour; Fatemeh Sadat Fatah; Mohammad Javad Ashraf; Mehrnaz Tahmasebi

Volume 11, Issue 4 , October 2016, , Pages 334-344

Abstract
  Background: In cancers of prostate, breast, oropharynx, lung, hypopharynx and skin, human tissue kallikreins has been demonstrated as a main role in these problems. There are many research works in which some human tissue kallikreins are expressed in salivary glands. In the present study, the main goal ...  Read More

Microbiology
Role of Aders and OXA23 Genes among Imipenem Resistant Acinetobacter baumannii Isolates from Two Hospitals of Tehran, Iran

Helia Ostad Asadolah-Malayeri; Mojdeh Hakemi-Vala; Kambiz Davari

Volume 11, Issue 4 , October 2016, , Pages 345-353

Abstract
  Background: This study aimed to evaluate the role of efflux pump regulator and OXA-23 genes in imipenem resistance Acinetobacter baumannii strains isolated from hospitalized patients in Tehran, Iran. Methods: This study was conducted on 60 A. baumannii isolates collected from patients admitted to the ...  Read More

Dermatopathology
A Case-Control Study on the Take-Off Sign in Lesional Skin Biopsies of Patients with Pityriasis Rosea

Antonio An Tung Chuh; Vijay Zawar; Gayatri Karad

Volume 11, Issue 4 , October 2016, , Pages 416-417

Abstract
  Dear Editor-in-Chief   Lesional histopathological features in pityriasis rosea (PR) are non-specific (1).  Our aim here is to investigate whether a histopathological take-off sign (TOS) is associated with PR.  Read More

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