Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Number of Volumes 17
Number of Issues 68
Number of Articles 892
Number of Contributors 2,864
View Per Article 1560.59
PDF Download Per Article 881.4
Number of Submissions 1,978
Number of Indexing Databases 49
Number of Reviewers 666
 

Iranian Journal of Pathology (Iran J Pathol)

Quarterly Journal of Anatomical and Clinical Pathology

The IRANIAN JOURNAL OF PATHOLOGY (IJP),  is an Open Access journal and publishes original research papers, reviews, case reports, short communications, and letters to the editor with priority for high-quality original papers on mechanisms of disease and clinical trials. We accept manuscripts that report important findings on disease pathogenesis and basic biological mechanisms that relate to disease without preferences for a  specific method of analysis. High priority is given to studies on human diseases and relevant experimental models that use cellular, molecular, biochemical & immunological approaches in conjunction with morphology, and to manuscripts that report new diagnostic methods or analytical systems and their application in studies of disease pathogenesis and diagnosis.   

 

  • Bone and Soft Tissue Pathology,
  • Dermatopathology,
  • Biochemistry,
  • Biology & Genetic,
  • Infectious Diseases,
  • Microbiology,
  • GI pathology & Hepatopathology,
  • Endocrine Pathology,
  • ENT & Ophthalmic Pathology,
  • Gynecologic & Breast Pathology,
  • Molecular Pathology,
  • Nephropathology,
  • Neuropathology,
  • Neuroscience and Anatomy,
  • Oncology & Hematology,
  • Oral Pathology,
  • Pediatric Pathology,
  • Surgical Pathology,
  • Diagnostic Pathology,
  • Uropathology

 

                     Publons  

 

Review Article Diagnostic Pathology
Comprehensive Assessment of Multiple Sclerosis: From Immunotherapy and Immunopathogenesis to Predictive Biomarkers

Soheil Vazifedust; Hadi Esmaeili Gouvarchin Ghaleh; Mostafa Khafaei; Fateme Azemati; Bahman Jalali Kondori

Volume 17, Issue 3 , July 2022, Pages 241-250

https://doi.org/10.30699/ijp.2022.541483.2755

Abstract
  Background & Objective: Multiple sclerosis (MS) is an inflammatory neurological disorder that affects the central nervous system (CNS) and causes individuals to experience a variety of cognitive and physical problems. As proven by two decades of clinical experience with immunomodulatory therapies ...  Read More

Original Research Breast Pathology
SNHG6 203 RNA May be Involved in the Cell Cycle Progression in HER2-Negative Breast Cancer Cells

Amin Jafari Oliayi; Shahriar Dabiri

Volume 17, Issue 3 , July 2022, Pages 251-260

https://doi.org/10.30699/ijp.2022.527346.2607

Abstract
  Background & Objective: Long noncoding RNAs (lncRNAs) as challenging molecules are more known compared to those in the  last decade. These transcripts have been validated for carcinogenesis in many types of tissue. Functions of lncRNAs in cancer induction include cell cycle, epithelial to mesenchymal ...  Read More

Original Research Microbiology
Phenotypic and Molecular Characterization of Carbapenems Resistant Escherichia coli Isolated from Patients with Urinary Tract Infections in Ardabil Province, Iran

Shabnam khavandi; Mohsen Arzanlou; Roghayeh Teimourpour; Hadi Peeridogaheh

Volume 17, Issue 3 , July 2022, Pages 261-267

https://doi.org/10.30699/ijp.2022.538613.2716

Abstract
  Background & Objective: Carbapenem-resistant is Gram-negative bacteria representing a worldwide public health problem. The present study aims to survey the phenotypic and genotypic characteristics of carbapenem-resistant Escherichia coli isolates collected from hospitalized patients and outpatients ...  Read More

Original Research Breast Pathology
Revisiting Metaplastic Carcinoma of Breast: An Emphasis on the Clinico-pathological and Immunohistochemical Variables Analyzed at a Tertiary Cancer Centre in South India

Geetha V Patil Okaly1; Akshatha C; Sandhya N; Akina Prakash; M N Suma; Ashwini Nargund; Shankar Anand; C Ramachandra; Libin Babu Cherian

Volume 17, Issue 3 , July 2022, Pages 268-274

https://doi.org/10.30699/ijp.2022.541798.2757

Abstract
  Background & Objective: Metaplastic carcinoma is a diverse variant of invasive breast carcinomas (IBC) characterized by dedifferentiation of malignant cells towards squamous and/or mesenchymal elements. It accounts for 0.3-1.2% of all IBC. These tumors are typically triple-negative by hormonal profiling ...  Read More

Original Research Head and Neck Pathology
Study of Podoplanin Expression in Head and Neck Squamous Cell Carcinoma

Anjali Mary JIbi; Vijaya Basavaraj

Volume 17, Issue 3 , July 2022, Pages 275-284

https://doi.org/10.30699/ijp.2022.547004.2809

Abstract
  Background & Objective: Head and Neck Squamous cell carcinoma (HNSCC) is one of the leading cancers worldwide. Cervical lymph node metastasis is the most adverse prognostic factor for patients with HNSCC. As there are no reliable factors in predicting lymph node metastasis, recent researchers focus ...  Read More

Original Research Microbiology
Anti-biofilm Activity of a Lytic Phage Against Vancomycin-Resistant Enterococcus faecalis

Forough Goodarzi; Masoumeh Hallajzadeh; Mohammad Sholeh; Malihe Talebi; Vahid Pirhajati Mahabadi; Nour Amirmozafari

Volume 17, Issue 3 , July 2022, Pages 285-294

https://doi.org/10.30699/ijp.2022.541855.2760

Abstract
  Background & Objective: This study aims to isolate a lytic bacteriophage against planktonic Enterococcus faecalis V583 culture and evaluate its ability to disrupt and inhibit biofilm.Methods: An anti-E. faecalis phage was isolated from sewage and visualized by electron microscopy, the vB_EfsS_V583 ...  Read More

Original Research Microbiology
The Antibacterial and Anti-biofilm Traits of the Novel BMAP-27-Melittin Conjugated Peptide Nanoparticle Against Streptococcus mutans: Clinical Isolates from Oral Cavity

Mohammad Pourahmadi; Kimia Pourahmadi; Farzan Modaresi; Shekoufeh Atashpoor; Azita Azad; Alireza Ranjbaran; Abdolmajid Ghasemian

Volume 17, Issue 3 , July 2022, Pages 294-302

https://doi.org/10.30699/ijp.2022.547555.2817

Abstract
  Background & Objective: The spread and development of drug-resistant bacterial strains has prompted the hunt for novel antibacterial polypeptides undergoing conformational changes to confer rapid bactericidal effects. The aim of this study was to evaluate the effect of novel BMAP27-Melittin conjugated ...  Read More

Original Research Microbiology
Evaluation of Triple Fragment Vaccine HSPX (Rv2031c) + PPE44 (Rv2770c) + Mouse IgG1 (Fcγ2a) with Auxiliary Adjuncts IL-22 in Comparison with BCG Vaccine

Azar valizadeh; Fra Khosravi; hamid sedighian; Elham Behzadi; Elaheh Parizad; Abbas Ali Imani Fooladi

Volume 17, Issue 3 , July 2022, Pages 303-313

https://doi.org/10.30699/ijp.2022.549673.2849

Abstract
  Background & Objective: Despite the vaccination with the BCG vaccine, tuberculosis (TB) remains one of the major health problems in the world. The aim of this study was to evaluate our newly designed vaccine using IL-22 as an adjuvant in comparison with the common BCG vaccine.Methods: The gene constructs ...  Read More

Original Research Breast Pathology
Crosstalk Between Programmed Death Ligand 1, Ki-67 Labelling Index, and Tumor-Infiltrating Lymphocytes in Invasive Breast Cancer and Clinicopathological Correlations in a Tertiary Care Center in Western India

Rashim Sharma; Poonam Abhay Elhence; Meenakshi Rao; Sudeep Khera; Deepak Vedant; Ramkaran Chaudhary; Puneet Pareek; Jeewan Ram Vishnoi; Sanjeev Misra

Volume 17, Issue 3 , July 2022, Pages 314-322

https://doi.org/10.30699/ijp.2022.539946.2737

Abstract
  Background & Objective: Breast cancer is the leading cancer among Indian women and accounts for about 25% of all cancer cases worldwide. The present study aimed to assess Programmed Death Ligand-1 (PD-L1) expression in tumoral cells and tumor-infiltrating lymphocytes (TILs) and evaluate their correlations ...  Read More

Original Research Biochemistry
Evaluation of the Relationship Between Serum and Urine Ferritin Level of Low Birth Weight Infants

Hassan Bazmamoun; Soheila Narimani; Maryam Shokohi; Hossein Esfahani; Ali Reza Soltanian; Alireza Rastgoo Haghi

Volume 17, Issue 3 , July 2022, Pages 323-327

https://doi.org/10.30699/ijp.2022.546540.2807

Abstract
  Background & Objective: Iron deficiency before birth or in infancy can cause long-term behavioral and neurological disorders. Measuring serum ferritin is an effective way to diagnose iron deficiency but requires significant blood volume from a low birth weight infant. Therefore, the present study ...  Read More

Original Research Uropathology
Accuracy of Paris 2016 System for Non-invasive Diagnosis Bladder Malignancy

Azadeh Rakhshan; Esmat Arvin; Sam Alahyari; Behrang Kazeminezhad; Tahmineh Mollasharifi; Alireza Bagheri; Fereshte Aliakbari; Seyed Jalil Hosseini; Mohammad Soleimani; Mahsa Ahadi; Elena Jamali; Afshin Moradi; Zahra Sadeghzadeh; Saleh Ghiasi; Malihe Nasiri; Farzad Allameh

Volume 17, Issue 3 , July 2022, Pages 328-334

https://doi.org/10.30699/ijp.2022.548036.2833

Abstract
  Background & Objective: The Paris System for Reporting Urinary Cytology (TPS) is a new method for evaluating urinary cytology designed to reduce unreproducible reports. The aim of this study was to reclassify and compare urinary cytology reports with TPS criteria to determine the frequency of unreproducible ...  Read More

Original Research Transfusion Medicine
Long-term Effects of Regular Whole Blood Donation on Peripheral Blood CD34+ Cells Population with using Leukoreduction Filters

Parvaneh Abbasi Sourki; Ali Akbar Pourfathollah; Mahdi Pakjoo; Zahra Abbasi-Malati; Mona A. A. Tajrishi

Volume 17, Issue 3 , July 2022, Pages 335-341

https://doi.org/10.30699/ijp.2022.540459.2746

Abstract
  Background & Objective: Trapped cell population in leukoreduction filters (LRFs) contains such a significant number of CD34+ hematopoietic stem cells that can be recovered to be used in research studies.Methods: Samples (n=20) were obtained from 10 first-time donors and 10 regular blood donors with ...  Read More

Original Research Neuropathology
Alpha-Synuclein Clearance through Inhibiting Akt/mTOR Pathway by Microfluidic Encapsulated Induced Conjunctival MSCs in a Parkinsonian Model

Meysam Forouzandeh; Mohammad Reza Bigdeli; Hossein Mostafavi; Samad Nadri; Mehdi Eskandari

Volume 17, Issue 3 , July 2022, Pages 342-353

https://doi.org/10.30699/ijp.2022.553459.2890

Abstract
  Background & Objective: Parkinson's disease (PD) is a progressive neurodegenerative disorder in which the cause is attributed to the alpha-synuclein (α-Syn) accumulation due to the decreased rate of autophagy. Due to the many advantages, mesenchymal stem cells (MSCs), such as the secretion ...  Read More

Short Communication Ophthalmopathology
Histopathology Study of Patients with Delayed Mustard Gas Keratopathy 30 Years After Exposure

Seyed Hashem Daryabari; Hossein Aghamollaei; Fahimeh Asadi Amoli; Khosrow Jadidi; Hamid Tebyanian

Volume 17, Issue 3 , July 2022, Pages 354-359

https://doi.org/10.30699/ijp.2022.538950.2722

Abstract
  Background & Objective: Delayed mustard gas keratopathy (DMGK) is the main chronic outcome in eye-chemical injured patients. The aim of this study was the histopathological evaluation of mustard-exposed cornea after more than 30 years.Methods: Fourteen corneas after Lamellar keratoplasty were evaluated ...  Read More

Case Reports Dermatopathology
Foamy Cell Angiosarcoma in a Patient with Xeroderma Pigmentosum: A Case Report and Comprehensive Review of the Literature

Fatemeh Montazer; Ali Zare Dehnavi; Abbas Dehghani; Arash Maboudi; Azadeh Goodarzi

Volume 17, Issue 3 , July 2022, Pages 360-370

https://doi.org/10.30699/ijp.2022.539239.2729

Abstract
  Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder characterized by a DNA repair defect caused by ultraviolet light and cutaneous manifestations, including solar lentigines, xerosis, actinic damage, and cutaneous neoplasms (e.g., basal cell carcinoma, squamous cell carcinoma, and melanoma). ...  Read More

Case Reports Gynecologic Pathology
A Young Iranian Woman with Pure Primary Ovarian Neuroendocrine Tumor: A Case Report

Fatemeh Samiee Rad; Mehdi Ghaebi; Arezoo Bajelan

Volume 17, Issue 3 , July 2022, Pages 371-375

https://doi.org/10.30699/ijp.2022.542788.2766

Abstract
  Pure ovarian neuroendocrine tumors are very rare. Herein, we present a young Iranian woman with a pure primary ovarian neuroendocrine tumor.A 26-year-old female presented with chronic abdominal pain and progressive constipation and was referred to the emergency room. Imaging findings confirmed a mass ...  Read More

Case Reports Oral Pathology
A Rare Case of Intra-Oral Dirofilariasis Manifesting on The Buccal Mucosa

Rakesh Suresh; Mahija Janardhanan; Vindhya Savithri; Thara Aravind

Volume 17, Issue 3 , July 2022, Pages 376-380

https://doi.org/10.30699/ijp.2022.548111.2829

Abstract
  Dirofilariasis is a rare zoonotic disease endemic in tropical and sub-tropic countries, including India. Caused by the nematode of the genus Dirofilaria, the disease usually affects canines which form the primary hosts. Humans rarely get infected through the bite of potential mosquito vectors. Manifestations ...  Read More

Neuropathology
The Role of Micro RNAs in Regulating PI3K/AKT Signaling Pathways in Glioblastoma

Roshanak Ghaffarian Zirak; Hurie Tajik; Jahanbakhsh Asadi; Pedram Hashemian; Hossein Javid

Volume 17, Issue 2 , April 2022, , Pages 122-136

https://doi.org/10.30699/ijp.2022.539029.2726

Abstract
  Glioblastoma is a type of brain cancer with aggressive and invasive nature. Such features result from increased proliferation and migration and also poor apoptosis of glioma cells leading to resistance to current treatments such as chemotherapy and radiotherapy. In recent studies, micro RNAs have been ...  Read More

Microbiology
Changes of Routine Hematological Parameters in COVID-19 Patients: Correlation with Imaging Findings, RT-PCR and Outcome

Abdolreza Javadi; Shahriar Dabiri; Manzumeh Shamsi Meymandi; Mohammad Hashemi-Bahremani; Hussein Soleimantabar; Bahram Dabiri; Houman Vosough; Maryam Gheidi Sharan; Farnoosh Sedaghati

Volume 17, Issue 1 , January 2022, , Pages 37-47

https://doi.org/10.30699/ijp.2021.533645.2675

Abstract
  Background & Objective: Coronavirus disease 2019 (COVID-19) is progressively spreading, and many researchers have focused on the prognostic value of laboratory analyses. This study reviewed routine blood parameters, upper respiratory viral load, and chest imaging in recovered and expired COVID-19 ...  Read More

Infectious Diseases
Effects of Human Nucleolus Upon Guest Viral-Life, Focusing in COVID-19 Infection: A Mini- Review

Moslem Bahadori; Mohammad Hossein Azizi; Shahriar Dabiri; Neda Bahadori

Volume 17, Issue 1 , January 2022, , Pages 1-7

https://doi.org/10.30699/ijp.2021.540305.2744

Abstract
  The nucleolus is a subcellular membraneless structure of eukaryotic cells. In 1965, in a world’s southern summer summit in Uruguay, the role of the nucleolus as the site of ribosome synthesis, biogenesis, and processing of tRNA was conclusively established. Today, accumulating evidence confirm ...  Read More

Cytology
Histopathological Findings of Testicular Tissue Following Cadmium Toxicity in Rats

Saeedeh Shojaeepour; Shahriar Dabiri; Bahram Dabiri; Masoud Imani; Maryam Fekri Soofi Abadi; Fatemeh Hashemi

Volume 16, Issue 4 , August 2021, , Pages 348-353

https://doi.org/10.30699/ijp.2021.130581.2443

Abstract
  Background & Objective: Reproductive toxicity of cadmium (Cd) as an environmental toxicant has been proved in animals and humans. Exposure to Cd impairs testes organs and can reduce male fertility. The present study was designed to investigate the spectrum of histopathological changes in testicular ...  Read More

Cytology
Cytogenetic Studies of 608 couples with Recurrent Spontaneous Abortions in Northeastern Iran

Narjes Soltani; Farzaneh Mirzaei; Hossein Ayatollahi

Volume 16, Issue 4 , August 2021, , Pages 418-425

https://doi.org/10.30699/ijp.2021.521514.2554

Abstract
  Background & Objective: One of the major genetic causes of recurrent spontaneous abortions is parental chromosomal abnormalities. The objectives of the study were to determine, compare and analyze the incidence and distribution of chromosomal abnormalities in couples with recurrent miscarriages from ...  Read More

Review Article GI, Liver & Pancreas Pathology
Algorithmic Approach to Inflammatory Disorders of Ileum

Afshin Moradi; Ali Mokhtar pour; Amir Yazdani; Kianoosh Kianersi; Leila Bahari Khasraghi

Articles in Press, Accepted Manuscript, Available Online from 10 September 2022

https://doi.org/10.30699/ijp.2022.539357.2736

Abstract
  The ileum undergoes endoscopic biopsy much more than before. Most of these biopsies are either completely normal or show non-specific changes. Nevertheless, in some diseases, ileal biopsy is diagnostic, and in some cases it may be the only anatomical location of the disease. Endoscopically normal mucosal ...  Read More

Review Article Molecular Pathology
Genetic and Epigenetic Alterations in Parathyroid Neoplasms

Seyed Amir Miratashi Yazdi; Elham Nazar

Articles in Press, Corrected Proof, Available Online from 25 August 2022

https://doi.org/10.30699/ijp.2022.551233.2865

Abstract
  The etiology of parathyroid carcinoma (PC) is largely unknown. Associations have been made with several inherited syndromes and with specific genetic lesions. The management of PC is challenging for clinicians. The complexity of molecular phenotypes increases with tumor aggressiveness. Lack of parafibromin ...  Read More

Original Research Breast Pathology
Preoperative Neutrophil: Lymphocyte Ratio, Platelet: Lymphocyte Ratio, and C-Reactive Protein Levels Predictive Value in Determining the Severity of Breast Mass

Aida Alizamir; Sakineh Dehghan Azad; Azar Pirdehghan; Arash Moradi

Articles in Press, Accepted Manuscript, Available Online from 02 September 2022

https://doi.org/10.30699/ijp.2022.539042.2727

Abstract
  Background & Objective: Female breast cancer is one of the most prevalent malignancies among women. The critical step in managing breast cancer is to diagnose it accurately. Hence, peripheral blood-based tests are one of the most favorable and less invasive methods to study. Recent studies investigated ...  Read More

Original Research Cardiovascular Pathology
Assessment of Neutrophil Extracellular Traps (NETs) and Macrophage Ratio in the Inner and Outer Area of Carotid Artery Stenosis

Shirin Saberianpour; Mohammad Mahdi Saeed Modaghegh; Mohammad Mahdi Kamyar

Articles in Press, Accepted Manuscript, Available Online from 28 August 2022

https://doi.org/10.30699/ijp.2022.538238.2713

Abstract
  Background & Objective: It is noteworthy that vast data links NETs to human arterial thrombosis. In the current study, extracellular neutrophil networks and macrophage polarization were assessed in the area outside and inside the Carotid artery stenosis.Methods: The sample of Carotid plaque of the ...  Read More

Original Research Bone & Soft tissue Pathology
Evaluation of FLT3-ITD Mutations and MDR1 Gene Expression in AML Patients

ehsan yazdandoust; mohammad hadidi sadeghian; seyyede fatemeh shams; Yasaman Saadatpour; payam siyadat; maryam sheikhi; Monavar Afzal Aghaee; Hossein Ayatollahi

Articles in Press, Accepted Manuscript, Available Online from 20 September 2022

https://doi.org/10.30699/ijp.2022.543485.2776

Abstract
  Background & Objective: Acute myeloid leukemia (AML) is a hematopoietic malignancy caused by genetic abnormalities. These days, molecular and genetic factors are usually used as diagnostic and prognostic markers. FLT-3 is one of the most known diagnostic factors in AML. MDR1 gene belongs to the ATP ...  Read More

Original Research Biochemistry
Thyroid Stimulating Hormone, T3 and T4 Population-based Reference Range and Children Prevalence of Thyroid Dysfunction: First Report from South of Iran

Mansoureh Shokripour; Mohammad Hadi Imanieh; Saghar Garayemi; Navid Omidifar; Babak Shirazi Yeganeh; Fadhil Althabhawee

Articles in Press, Corrected Proof, Available Online from 13 September 2022

https://doi.org/10.30699/ijp.2022.541736.2812

Abstract
  Background & Objective: The TSH reference range's validity affects the thyroid dysfunction diagnosis. The primary objective of this study is to determine the reference range, which is established according to age and region. Methods: The data were collected retrospectively from people over the age ...  Read More

Original Research Breast Pathology
Carcinoma Breast – A Comparative Study of Immunohistochemistry and Fluorescence in Situ Hybridization for Her-2 Assessment and Association of Er, Pr, Her-2 and Ki-67 Expression with Clinico-Pathological Parameters

Sajitha K; Meenakshi Arumugam; Jayaprakash Shetty; Reshma A Shetty; Ritu Asnani; Prashanth Shetty

Articles in Press, Corrected Proof, Available Online from 02 September 2022

https://doi.org/10.30699/ijp.2022.538167.2712

Abstract
  Background & Objective: Breast cancer is the most common cancer in developed and developing countries. This study mainly addresses the issue of an equivocal result in IHC, which then needs further assessment if the patient has to receive targeted therapy. The study aimed to detect the expression ...  Read More

Original Research Immunology and Serology
Immune Response in Mice Immunized with Recombinant PreS2/S-C18-27 Protein from Hepatitis B Virus Compared with Commercial Vaccine

Elaheh Gholami Parizad; Abbas Ali Imani Fooladi; Hamid Sedighian; Elham Behzadi; Azar valizadeh; Afra Khosravi

Articles in Press, Accepted Manuscript, Available Online from 02 September 2022

https://doi.org/10.30699/ijp.2022.553785.2896

Abstract
  Background & Objective: The vaccine available to prevent Hepatitis B virus disease is ineffective in 5% of people due to the use of HBsAg as a weak immunogen. In the present study, PreS2/S fused to C18-27 peptide fragment as an effective antigen and is proposed as a promising vaccine candidate compared ...  Read More

Original Research Infectious Diseases
Topical Treatment of Second-Degree Burn Wounds with Lactobacillus plantarum Supernatant: Phase I Trial

Somayeh Soleymanzadeh Moghaddam; Mahnoush Momeni; Samaneh Mazar Atabaki; Tahereh Mousavi Shabestari; Mina Boustanshenas; Mastaneh Afshar; Maryam Roham

Articles in Press, Accepted Manuscript, Available Online from 04 September 2022

https://doi.org/10.30699/ijp.2022.551202.2863

Abstract
  Background & Objective: A burn wound is sterile immediately after injury, but opportunistic bacteria colonize the wound within 48 to 72 hours after the burn, causing delayed or failed burn wound healing. In addition, the presence of multidrug-resistant (MDR) pathogens doubles the treatment problems. ...  Read More

Original Research Oral Pathology
KRAS Protein Expression in Oral Squamous Cell Carcinoma: A Potential Marker for Progression and Prognosis

Hala M. El-hanbuli; Mostafa A. Abou Sarie

Articles in Press, Corrected Proof, Available Online from 10 September 2022

https://doi.org/10.30699/ijp.2022.550727.2856

Abstract
  Background & Objective: Emerging evidence suggests that KRAS could play an important role in squamous cell carcinoma; however, its role in oral squamous cell carcinoma (OSCC) is largely unknown. The aim of the current study was to investigate the expression of KRAS, Ki-67, Cyclin D1, and Bcl2 in ...  Read More

Case Reports Diagnostic Pathology
A Rare Case of Cardiac Metastasis from Colon Cancer

Zahra Modabber; Roghayeh Pourkia; Hamidreza Vafaey; Ali Alizadeh; Mohammad Ranaei

Articles in Press, Accepted Manuscript, Available Online from 02 September 2022

https://doi.org/10.30699/ijp.2022.551822.2874

Abstract
  It is very rare for colorectal neoplasms to metastasize to the heart in the worldwide medical literature; only a single case of well-documented colorectal cancer metastasis to the left atrium was found. The case of a 66-year-old man is explained in this paper, who was suffering from metastatic adenocarcinoma ...  Read More

Case Reports Nephropathology
Crescentic Glomerulonephritis, A Rare Presentation of Alport Syndrome

Tahereh Malakoutian; Fatemeh Nili; Sholeh Ghasemi Darbrood; Samaneh Salarvand; Mitra Mehrazma

Articles in Press, Corrected Proof, Available Online from 02 September 2022

https://doi.org/10.30699/ijp.2022.554160.2899

Abstract
  Crescentic glomerulonephritis (GN) is a feature of severe glomerular injury. Anti-GBM disease, immune-complex mediated glomerulonephritis, and ANCA-associated vasculitis are the main causes of crescentic GN. Alport syndrome is a progressive form of hereditary nephritis presenting with hematuria and progression ...  Read More

Microbiology
Role of Aders and OXA23 Genes among Imipenem Resistant Acinetobacter baumannii Isolates from Two Hospitals of Tehran, Iran

Helia Ostad Asadolah-Malayeri; Mojdeh Hakemi-Vala; Kambiz Davari

Volume 11, Issue 4 , October 2016, , Pages 345-353

Abstract
  Background: This study aimed to evaluate the role of efflux pump regulator and OXA-23 genes in imipenem resistance Acinetobacter baumannii strains isolated from hospitalized patients in Tehran, Iran. Methods: This study was conducted on 60 A. baumannii isolates collected from patients admitted to the ...  Read More

Microbiology
Isolation of indigenous Glutathione producing Saccharomyces cerevisiae strains

Tahereh Tahmasebi; Rahim Nosrati; Hamed Zare; Horieh Saderi; Reyhaneh Moradi; Parviz Owlia

Volume 11, Issue 4 , October 2016, , Pages 354-362

Abstract
  Background: Glutathione (GSH) is a non-protein thiol compound, which plays an important role in the response to oxidative stress and nutritional stress. The aim of this study was to isolate indigenous S. cerevisiae strains capable of effectively produce GSH. Methods: One hundred-twenty sweet fruit samples ...  Read More

Correlation of P16 (Ink4a) and CK17 to HPV (16E6+18E6) in Premalignant and Malignant Lesions of Uterine Cervix: A Clinicopathologic Study

Mohammed Chaloob; Alaa G. Hussein; Ban Qasim

Volume 11, Issue 4 , October 2016, , Pages 377-390

Abstract
  Background: This research was accomplished to evaluate the IHC expression of p16 (ink4a) and CK17 in low grade cervical intraepithelial lesions (LSIL), high grade cervical intraepithelial lesions (HSIL) and invasive cervical carcinomas and to assess their correlation to HPV (16E6+18E6). Methods: The ...  Read More

Oral Pathology
A Rare Case of Pilomatrixoma (Calcifying Epithelioma of Malherbe) of Parotid Space Masquerading as Salivary Gland Tumor

Manas Bajpai; Manika Arora; Betina Chandolia

Volume 11, Issue 4 , October 2016, , Pages 418-420

Abstract
  Dear Editor-in-Chief   Pilomatrixoma is a benign tumor of hair follicle first described as calcifying epithelium (1). It accounts for 1% of all the benign skin tumors (2). It is a slow-growing, firm, dermal or subcutaneous neoplasm, usually measuring fewer than 3 cm in diameter. Pilomatricomas ...  Read More

Hairy Cell Leukemia in a Young Male: An Unusual Presentation

Manveen Kaur; Koushik Kar; Varsha Dalal; Fouzia Siraj

Volume 11, Issue 4 , October 2016, , Pages 421-422

Abstract
  Dear Editor-in-Chief A 28 yr male was presented in October 2015 at Medicine Outpatient Department, Safdarjung Hospital, New Delhi- India with generalized weakness, fever and cough for preceding 15 days. Clinicoradiologic examination revealed pallor, firm, non-tender splenomegaly measuring 13.7 cm and ...  Read More

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