Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Comparing the Efficacy of Virtual and Conventional Methods in Teaching Practical Pathology to Medical Students

Alireza Abdollahi; Samaneh Salarvand; Hiva Saffar

Volume 13, Issue 2 , April 2018, Pages 108-112


  Electronic learning introduces a teaching device for deeper and more efficient learning. A study was conducted by the Pathology Department of Tehran University of Medical Sciences, Tehran, Iran. The topic of practical pathology was selected earlier based on the curriculum. High-quality digital images ...  Read More

Review Article Microbiology
Development of Preventive Vaccines for Hepatitis C Virus E1/E2 Protein

Faezeh Ghasemi; Majid Ghayour Mobarhan; Hamed Gouklani; Zahra Meshkat

Volume 13, Issue 2 , April 2018, Pages 113-124


  Hepatitis C virus (HCV) is responsible for a vast majority of liver failure cases. HCV is a kind of blood disease appraised to chronically infect 3% of the worlds’ population causing significant morbidity and mortality. Therefore, a complete knowledge of humoral responses against HCV, resulting ...  Read More

Review Article Biology & Genetic
A Review of Driver Genetic Alterations in Thyroid Cancers

Fatemeh Khatami; Mohammad Tavangar

Volume 13, Issue 2 , April 2018, Pages 125-135


  Thyroid cancer is a frequent endocrine related malignancy with continuous increasing incidence. There has been moving development in understanding its molecular pathogenesis recently mainly through the explanation of the original role of several key signaling pathways and related molecular distributors. ...  Read More

Original Research
Colonization of Pneumocystis jirovecii in Patients who Received and not Received Corticosteroids Admitted to the Intensive Care Unit: Airborne Transmission Approach

Behnam Mohammadi-Ghalehbin; Shahram Habibzadeh; Mohsen Arzanlou; Roghayeh Teimourpour; Saeideh Amani Ghayum

Volume 13, Issue 2 , April 2018, Pages 136-143


  Background & objective: Pneumocystis pneumonia (PCP) is responsible for pulmonary infection in immunocompromised patients. This study aimed to investigating the frequency of Pneumocystis colonization in patients hospitalized in the intensive care unit (ICU) and evaluating the relationship between ...  Read More

Original Research
Molecular Genotyping of Acinetobacter baumannii Species Isolated from Patients in Tehran, Iran, by Repetitive Element PCR Fingerprinting

Baharak Kian; Reza Mirnejad; Shiva Mirkalantari; Gholamali Moradli; Reza Golmohammadi

Volume 13, Issue 2 , April 2018, Pages 144-150


  Background & Objective: Acinetobacter baumannii is an opportunistic pathogen with high pathogenic and antibiotic-resistance potential and is also considered as one of the main nosocomial agents, specifically in the intensive care units (ICUs). It is highly important to use molecular biology methods ...  Read More

Original Research
Immunohistochemical Evaluation of β-catenin Marker in Papillary Thyroid Cancer Clinicopathologic Behavior

Katayoun Ziari; Mojgan Sanjari; Moeinadin Safavi

Volume 13, Issue 2 , April 2018, Pages 151-156


  Background & objective: papillary thyroid cancer is the most common cancer of thyroid accounting for 75%-85% of all thyroid malignancies. Recently, β-catenin has been determined to play a role in clinical course of human epithelial cancers. This study was designed to reveal the association of ...  Read More

Original Research Biochemistry
Association of Sulfur Mustard-induced Ocular Problems with Serum and Blood Biochemical Parameters Changes

Hassan Ghasemi; Nayere Askari; Mohammad Mehdi Naghizadeh; Susan Kabudanian Ardestani; Sakine Moaiedmohseni; Mohammad-Reza Vaez-Mahdavi; Tooba Ghazanfari

Volume 13, Issue 2 , April 2018, Pages 157-166


  Background and objective:Many biochemical features of sulfur mustard (SM) intoxication remained unknown. So far, the direct association between biochemical parameter changes and ocular problems in patients exposed to SM is not evaluated.The current study aimed at evaluating the associations between the ...  Read More

Original Research Biology & Genetic
KRAS Codon 12 and 13 Mutations in Gastric Cancer in the Northeast Iran

Hossein Ayatollahi; Alireza Tavassoli; Amir Hossein Jafarian; Amin Alavi; Sepideh Shakeri; Seyyede Fatemeh Shams; Maryam Sheikhi; Neda Motamedi Rad; Mohammadhadi Sadeghian; Afsane Bahrami

Volume 13, Issue 2 , April 2018, Pages 167-172


  Background & objective: KRAS mutations are reported in many types of cancers including pancreas, lung, colon, breast, and gastric (GC). High frequency of KRAS mutation is observed in the pancreas, colon, and lung cancers; they commonly arise in codon 12 and 13 of exon 2. Due to the lack of information ...  Read More

Original Research Biochemistry
The Evaluation of Error Types and Turnaround Time of Preanalytical Phase in Biochemistry and Hematology Laboratories

Gokhan Cakirca

Volume 13, Issue 2 , April 2018, Pages 173-178


  Background& Objective: Each laboratory should determine the type of errors and turnaround time (TAT), especially in the preanalytical phase to report quality and timeliness of the test results. The current study aimed at investigating the common causes of preanalytical errors in biochemistry ...  Read More

Original Research
Comparative Evaluation of Cell Block Method and Smear Cytology in Fine Needle Aspiration Cytology of Intra-abdominal Mass Lesions

Sourav Bhowmik; Indranil Chakrabarti; Piyali Ghosh; Pranati Bera; Tarak Banik

Volume 13, Issue 2 , April 2018, Pages 179-187


  Background& Objective: Fine needle aspiration cytology (FNAC) is an easy, rapid, and less hazardous tool to diagnose the intra-abdominal lesions with various imaging modalities adding to its sensitivity and accuracy. However, sometimes it does not yield adequate information for precise diagnosis ...  Read More

Original Research
Diagnostic Utility and Efficacy of Conventional versus SurePath® Liquid-based Cytology in Head and Neck Pathology: A Study in an Indian Tertiary Care Hospital

Sonam Sharma; Charanjeet Ahluwalia; Mukul Singh; Ashish Mandal

Volume 13, Issue 2 , April 2018, Pages 188-195


  Background and Objective: Liquid-based cytology (LBC) is an emerging pathological method  for better  establishment of the diagnosis in almost all the organs of the body. It is currently used both for the gynecological and non-gynecological (fine-needle aspirates (FNAs)/fluid) specimens in ...  Read More

Original Research
Histomorphological and Immunohistochemical Analysis of Pleural Neoplasms

Sandhya Venkatachala; Swarna Shivakumar; Meganathan Prabhu; Ramya Padilu

Volume 13, Issue 2 , April 2018, Pages 196-204


  Background & objective:Primary pleural neoplasms are rare entities compared with the pleural involvement by metastatic carcinoma. The current study aimed at investigating the complete spectrum of pleural neoplasms and differentiating between them with the aid of immunohistochemistry (IHC). Methods: ...  Read More

Original Research
Assessment of Micro-vessel Density in Brain Glioma by CD105 Expression

Hiva Saffar; Marzieh Mirzaii; Elham Mirzaian2050@gmail.com; Farid Kosari

Volume 13, Issue 2 , April 2018, Pages 205-211


  Background& Objective: Micro-vascular proliferation is an important histological feature of brain glioma with more vascular proliferation is present in higher grades of glioma. CD 105 is expressed in new actively proliferating and immature endothelial cells in tumor environment  and appears ...  Read More

Original Research
The Correlation Between Serum Vitamin D Level and Total Antioxidant Capacity in diabetic and Non-diabetic Subjects in Iran

Ali Zare-Mirzaie; Behrang Kazeminezhad; Mona Akbari Ghouchani

Volume 13, Issue 2 , April 2018, Pages 212-219


  Background& Objective:  Increase in intra- and extracellular glucose levels can cause oxidative stress, and the prolonged imbalance between prooxidants and antioxidantscan lead to cell damage and the associated complications in patients with diabetes. Vitamin D acts as a strong antioxidant in ...  Read More

Original Research Oral Pathology
Risk-based Stratification of Salivary Gland Lesions on Cytology: An Institutional Experience

Pooja Jaiswal; Mousumi Sharma; Faraz Ahmad; Nausheen Sanaullah Khan; Siddhartha Sinha; Megha Agarwal

Volume 13, Issue 2 , April 2018, Pages 220-228


  Background and objective: Fine needle aspiration cytology (FNAC) of salivary gland lesions is an accepted and useful diagnostic tool to differentiate between benign and malignant lesions. Majority of the neoplasms are benign, and specific diagnosis on cytology can be made in most of the cases. However, ...  Read More

Original Research Biology & Genetic
The Association of Gastritis and Peptic Ulcer With Polymorphisms in the Inflammatory-related Genes IL-4 and IL-10 in Iranian Population

Meysam Rezaeishahmirzadi; Neda Motamedi Rad; Mehdi Kalantar; Hossein Ayatollahi; Sepideh shakeri; Maryam Sheikhi; Mohammad Shekari

Volume 13, Issue 2 , April 2018, Pages 229-236


  Background and Objective: The current study aimed at assessing the relationship between gastritis and peptic ulcer susceptibility and inflammation-related gene polymorphisms in Iranian patients. Gastritis and peptic ulcer are common medical complications with serious outcomes on the quality of life. ...  Read More

Original Research
Tissue Expression of Prohibition-I and Its Relationship With Prognostic Factors in Breast Cancer

Hossein Javid; Isaac Hashemy; Soudabeh Shahid sales; Nema Mohammadian Roshan; Tayyebeh Kianoosh; Farnaz Zahedi Avval

Volume 13, Issue 2 , April 2018, Pages 237-244


  Background & objective: Globally, breast cancer is the most common malignancy among females. Prohibition (PHB)-I, a homologous protein, was initially introduced as a suppressor gene for amplification process. Further, the protein has a key role in the cell cycle and is capable of inhibiting ...  Read More

Original Research
The Effect of Lavandula Stoechas on Toxigenesis and the Growth of Vibrio Parahaemolyticus

Omid Maghsoudi; Mohsen Zeraatkar; Mojtaba Dolatabadi; Ahmad Johari; Mahdi Barati Karizno; Reza Ranjbar

Volume 13, Issue 2 , April 2018, Pages 245-255


  Background and Objective:Outbreak of food-borne diseases has become more and more important these days and using natural food preservers with high durability is under debate. Vegetative essence is a type of food preserver and many studies have been performed on their antimicrobial effects. The purpose ...  Read More

Original Research
The Expression of FOXE-1 and STIP-1 in Papillary Thyroid Carcinoma and Their Relationship with Patient Prognosis

Enas M. Fouad; Ola A Harb; Reham Amin Salem; Ola M El farargy; Fady M Habib; Loay M Gertallah

Volume 13, Issue 2 , April 2018, Pages 256-271


   Background and Objective: Most patients with papillary carcinoma of the thyroid gland (PTC) have favorable outcome, but since it has severe capability to invade the nearby tissues, there is a great risk of regional and distal lymph-nodes (LNs) metastases related to poor prognostic parameters, early ...  Read More

Short Communication
Plasma Fibrinogen and D-dimer in Children With Sepsis: A Single-center Experience

Abhimanyu Sharma; Meera Sikka; Sunil Gomber; Satendra Sharma

Volume 13, Issue 2 , April 2018, Pages 272-275


  Background & Objectives:  In sepsis, enhanced fibrin formation, impaired fibrin degradation, and intravascular fibrin deposition lead to a prothrombotic state. The current study aimed at measuring various coagulation parameters to predict an early marker for disseminated intravascular coagulation ...  Read More

Case Reports
Squamous Cell Differentiation in Metastatic Papillary Thyroid Carcinoma: Metaplastic

Adriana Handra-Luca

Volume 13, Issue 2 , April 2018, Pages 276-280


  Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1)  and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck ...  Read More

Case Reports Hematopathology
Non Secretory Multiple Myeloma With HCV Infection: A Rare Case Entity

Arun Puri; Heena Wadhwa; Navtej Singh

Volume 13, Issue 2 , April 2018, Pages 281-284


  Multiple Myeloma is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells. It is characterized by a clinical  pentad of 1) anemia, 2) a monoclonal protein in the serum or the urine or both, 3) bone leisons and or bone pain, 4) hypercalcemia >11.5g/dl and ...  Read More

Case Reports Hematopathology
Cutaneous Verrucous Carcinoma Superimposed on Chronically Inflamed Ileostomy Site Skin: A Case Report

Ali Yaghobi; Payam Azadeh; Behzad Nemati Honar

Volume 13, Issue 2 , April 2018, Pages 285-288


  Verrucous carcinoma (VC) is a rare variant of well differentiated squamous cell carcinoma (SCC) which is usually found in oral cavity mucosa. Cutaneous verrucous carcinoma is a rare entity and in this paper we report a 43 years old man with VC superimposed on chronically inflamed skin of ileostomy site. ...  Read More

Case Reports Gynecologic Pathology
Hepatoid Variant of Yolk Sac Tumor of Both Ovaries With Widespread Intra-abdominal and Lung Metastasis: A Case Report

Srilatha Parampalli Srinivas; Archana Shivamurthy; Lakshmi Rao; Rajeshwari Gurumoorthy Bhat

Volume 13, Issue 2 , April 2018, Pages 289-293


  Hepatoid variant of yolk sac tumor of ovary is an unusual tumor with an aggressive behavior. It is usually observed in young females, presents with abdominal complaints and is associated with raised α-fetoprotein (AFP) levels. It should be differentiated from other hepatoid tumors involving the ...  Read More

Letters to the Editor
Molecular Diagnostic Methods of Brucellosis: a Note on Pitfalls

Massoud Hajia; Amir Sohrabi

Volume 13, Issue 2 , April 2018, Pages 294-295


  Clinical manifestations of the brucellosis may show extensive appearance because of its wide signs and symptoms. Patients with brucellosis are usually symptomatically treated by using different antibiotics at private clinics due to misdiagnosis of clinical laboratory findings specially those chronic ...  Read More