Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Gynecologic Pathology
The Association Between Higher Expression of Talin-1 and the Reduced Survival Rate in Ovarian Serous Carcinoma Patients

Mina Sharbatoghli; Leili Saeednejad Zanjani; Fahimeh Fattahi; Elham Kalantari; Zohre Habibi Shams; Mahshid Panahi; Mehdi Totonchi; Mohsen Asadi-Lari; Zahra Majd

Volume 18, Issue 3 , July 2023, , Pages 312-326


  Background & Objective: Talin-1 is a constituent of the multiprotein adhesion complexes that play  main role in the formation of tumors and migration in different types of malignancies. The present study aimed to assess  expression and prognostic significance of the talin-1 protein in ovarian ...  Read More

Gynecologic Pathology
The Relationship Between Leptin Receptor Expression and Endometrial Carcinoma; A Case-Control Study

Mojtaba Sehhat; Zahra Moshfegh Arani; Niyusha Niusha Lajevardi; Malek Reiesifar; Fahimeh Abdi Abyaneh; Zarichehr Vakili

Volume 18, Issue 2 , April 2023, , Pages 173-179


  Background & Objective: Endometrial carcinoma is one of the most common malignancies in women in developed countries and the fourth malignancy in Iranian women. Therefore, the identification of its causative factors is essential for the prevention, diagnosis, and treatment. This study was aimed to ...  Read More

Gynecologic Pathology
Placental Mesenchymal Dysplasia Associated with Severe Intrauterine Growth Restriction: A Case Report

Arshia Yazdani; Mohammad Ranaee; Sara Babazadeh; Fatemeh Shafizadeh

Volume 18, Issue 2 , April 2023, , Pages 221-224


  Placental mesenchymal dysplasia (PMD) is an uncommon placental lesion, which may mimic molar pregnancy at gross and microscopic examination. PMD can be associated with fetal growth restriction, Beckwith-Wiedemann syndrome, intrauterine fetal death, and preterm delivery. Nonetheless, it may also be associated ...  Read More

Gynecologic Pathology
Diagnostic Accuracy of Alpha-Methylacyl-CoA Racemase Immunohistochemical Expression for the Diagnosis of Ovarian and Endometrial Clear Cell Carcinomas

Fatemeh Nili; Soheib Fathi; Mansoureh Tavakoli; Elham Mirzaian; Maryam Lotfi

Volume 18, Issue 1 , January 2023, , Pages 57-63


  Background & Objective: Clear cell carcinoma (CCC) is an uncommon histopathologic subtype of ovarian and endometrial carcinoma. Due to the morphologic overlapping with other subtypes of ovarian and endometrial carcinomas, an accurate diagnosis is crucial.Methods: In this study, 31 cases of ovarian ...  Read More

Gynecologic Pathology
A Young Iranian Woman with Pure Primary Ovarian Neuroendocrine Tumor: A Case Report

Fatemeh Samiee Rad; Mehdi Ghaebi; Arezoo Bajelan

Volume 17, Issue 3 , July 2022, , Pages 371-375


  Pure ovarian neuroendocrine tumors are very rare. Herein, we present a young Iranian woman with a pure primary ovarian neuroendocrine tumor.A 26-year-old female presented with chronic abdominal pain and progressive constipation and was referred to the emergency room. Imaging findings confirmed a mass ...  Read More

Gynecologic Pathology
Significance of Endocan Expression in Various Types of Epithelial Ovarian Tumors

Maryam Entezarian; Fereshteh Ameli; Noraidah Masir; Tan Geok Chin

Volume 17, Issue 2 , April 2022, , Pages 202-209


  Background & Objective: Ovarian cancer is associated with the highest mortality rate among gynecologic malignancies. Despite new therapeutic strategies, ovarian cancer still has a high risk of metastasis and mortality. Endocan is a newly identified endothelial cell activation marker, which is responsible ...  Read More

Gynecologic Pathology
A Case of Premenopausal Uterine Leiomyoma, Non-cirrhotic Portal Fibrosis, Hepatic Koch's, a PET Gone Astray-Morphology Antidotes a Confounding Concoction

Kavita Gaur; Shailaja Shukla; Shinjini Choudhury; Pankaj Raj; Sharda Patra

Volume 17, Issue 2 , April 2022, , Pages 229-233


  Uterine leiomyoma with hepatic vasculopathy, specifically non-cirrhotic portal fibrosis (NCPF), has hitherto been undescribed. NCPF is characterized by elevated portal pressure sans cirrhosis and has previously not been described in association with a gynecological pathology. We report the case of a ...  Read More

Gynecologic Pathology
An Unusual Presentation of Giant Fibroepithelial Polyp of the Vagina

Azar Daneshpajooh; Mahboubeh Mirzaei; Maryam Iranpour

Volume 16, Issue 4 , August 2021, , Pages 456-460


  Fibroepithelial polyps of the vagina (FEPV) are rare entities which normally manifest as one or more painless polyps sometimes with symptoms such as bleeding, vaginal discharge, and discomfort regarding the size of the mass. Despite their benign nature, they can be confused with other vaginal tumors ...  Read More

Gynecologic Pathology
Chemotherapeutic Effect on Ovarian Stroma and Tumor Cells Which Make Problem in Diagnosis and Staging of Tumor

Neda Nasirian; Khadigeh Elmizadeh

Volume 16, Issue 4 , August 2021, , Pages 465-466


  Chemotherapy of ovarian tumors has some effects on morphology of stromal cells also residual tumoral cells which can cause problems in diagnosis of tumor type and staging of it .In some cases ,it can makes problem in diagnosis of residual epithelial tumor from other differential diagnosis such as spindle ...  Read More

Gynecologic Pathology
Improvement of Targeted Chemotherapy of HER2-positive Ovarian Malignant Cell Line by ZHER2-Idarubicin Conjugate: An in vitro Study

Lila Siavoshinia; Mostafa Jamalan; Majid Zeinali; Aminollah Pourshohod; Mahdie Koushki; Bahman Moradipoodeh; Ghorban Mohammadzadeh

Volume 16, Issue 2 , April 2021, , Pages 109-118


  Background & objectives: Overexpression of human epidermal growth factor receptor 2 (HER2) causes cell transformation and development of various types of malignancies. Idarubicin is an effective anti-neoplastic drug but specific delivery of it to the targeted cells is still a great challenge. Affibody ...  Read More

Gynecologic Pathology
Mesonephric Adenocarcinoma of Uterine Cervix; A Case Report and Review of the Literature

Fatemeh Nili; Samaneh Salarvand; Hana Saffar; Bita Kalaghchi; Reza Ghalehtaki

Volume 16, Issue 2 , April 2021, , Pages 227-231


  Mesonephric adenocarcinoma of the uterine cervix, an extremely rare tumor of the female genital tract, derives from the remnants of embryonic mesonephric ducts and its prognosis, diagnosis and treatment is rather challenging. We report a case of a 46-year-old woman with history of abnormal uterine bleeding ...  Read More

Gynecologic Pathology
Association of Human Papilloma Virus and Epstein-Barr Virus with Ovarian Cancer in Shiraz, Southwestern Iran

Mohammad Reza Shokouh; Akbar Safaie; Afagh Moattari; Jamal Sarvari

Volume 15, Issue 4 , October 2020, , Pages 292-298


  Background & Objective:  Ovarian cancer is one of the most common cancers amongst women. The association of Human papillomavirus (HPV) and Epstein-Barr virus (EBV) with ovarian cancer is inconclusive; therefore, the aims of this study were to evaluate the frequency of HPV and EBV in malignant, ...  Read More

Gynecologic Pathology
Coexistence of Benign Brenner Tumor with Mucinous Cystadenoma in an Ovarian Mass

Farzaneh Nazari; Zahra Dehghani

Volume 15, Issue 4 , October 2020, , Pages 334-337


  Ovarian cancer is the most lethal gynecologic malignancy. The surface epithelial tumor is the most common type of ovarian cancer. Among these, the mucinous tumors account for 10-15% of ovarian tumors. Mucinous ovarian tumors are among the most difficult ovarian neoplasms for surgical pathologists to ...  Read More

Gynecologic Pathology
Predicting Effects of Clinicopathological Variables on Her2 Gene Amplification by Chromogenic in situ Hybridization (CISH) in IHC Her2 (2+) Breast Cancer Patients; A Study from Iran

Mohammad Hashemi-Bahremani; Abdolali Ebrahimi; Mohaddese Fallahi

Volume 15, Issue 3 , July 2020, , Pages 217-224


  Background & Objective: The her2 amplification plays an important role in breast cancer management. Therefore, there is a need for using supplementary molecular methods in IHC equivocal cases. Present study has been conducted to determine the effects of clinicopathological variables on her2 gene ...  Read More

Gynecologic Pathology
Napsin-A Expression, a Reliable Immunohistochemical Marker for Diagnosis of Ovarian and Endometrial Clear Cell Carcinomas

Fatemeh Nili; Mansoureh Tavakoli; Narges Izadi-Mood; Hana Saffar; Soheila Sarmadi

Volume 15, Issue 2 , April 2020, , Pages 81-85


  Background & Objective: Clear cell carcinomas (CCC) differ from other types of ovarian and endometrial carcinomas in biology, behavior and response to chemotherapy. Histopathologic diagnosis may be challenging in some situations which necessitates immunohistochemistary (IHC) assessment. In this study ...  Read More

Gynecologic Pathology
Concurrence of Primary Cutaneous Extra Mammary Paget’s Disease and Squamous Cell Carcinoma in situ of Vulva: A Case Report

Fatemeh Samiee Rad; Sohayla Farajee

Volume 15, Issue 1 , January 2020, , Pages 48-52


  Extramammary Paget’s disease and vulvar intraepithelial neoplasia are common lesions of vulve, but synchronous occurrence is rare in a same location. Herein we describe a concurrence of primary cutaneous extra mammary Paget’s disease and squamous cell carcinoma in situ of vulva in an Iranian ...  Read More

Gynecologic Pathology
Absence of Human Papillomavirus in Benign and Malignant Breast Tissue

Maryam Kazemi Aghdam; Seyed Alireza Nadji; Azadeh Alvandimanesh; Maliheh Khoddami; Yassaman Khademi

Volume 14, Issue 4 , October 2019, , Pages 279-283


  Background & Objective: Malignant breast tumors, which are one of the most important deadly cancers in women, like many other cancers, are proposed to be related to viruses etiologically. Proper management of breast carcinoma necessitates an identification of the etiological factors. Human Papilomavirus is ...  Read More

Gynecologic Pathology
Evaluation of HER2/neu Expression in High-Grade Endometrial Carcinoma and Its Clinicopathological Correlation

Soheila Sarmadi; Narges Izadi-Mood; Nazanin Mansourzadeh; Dorna Motevalli

Volume 14, Issue 4 , October 2019, , Pages 322-328


  Background & Objective: Endometrial carcinoma (EC) has been traditionally classified into two distinct categories of low-grade and high-grade. Type I (low grade) EC, which constitutes the majority of cases, is linked to estrogen-related molecular pathways. But type II (high-grade) EC accounts for ...  Read More

Gynecologic Pathology
Comparing the Diagnostic Outcomes of Staining Various Breast Lesions with Either Anti-CK 5/6 or Anti-CK 5

Mihir A Gudi; Yiu Yi Chung; Nohadani Mahrokh

Volume 14, Issue 2 , April 2019, , Pages 113-121


  Background and Objective: Anti-CK5/6 monoclonal antibodies have an established role in breast disease diagnosis. Anti-CK5 monoclonal antibodies have recently become commercially available. There has been growing interest in the staining characteristics of anti-CK5 and its potential diagnostic role in ...  Read More

Gynecologic Pathology
Peripheral Primitive Neuroectodermal Tumor of the Ovary: The Report of Two Rare Cases

Fatemeh Nili; Azadeh Sedighi moghadam pour; Hedieh Moradi Tabriz; Parisa Sedighi Moghadam Pour; Hana Saffar

Volume 13, Issue 4 , October 2018, , Pages 467-470

  Peripheral primitive neuroectodermal tumor (pPNET) is a highly aggressive small round cell tumor belonging to PNET/Ewing sarcoma family. Ovarian tumors composed of primitive neuroectodermal elements are extremely rare. Herein we reported two cases of peripheral primitive neuroectodermal tumors of ovary ...  Read More

Gynecologic Pathology
Fallopian Tube Carcinoma In-situ in Endometrial Curettage

Nilay Nishith; Vidya Monappa; Ranjini Kudva

Volume 13, Issue 3 , July 2018, , Pages 363-367

  Background and Objective: Primary fallopian tube carcinomas (PFTC) are rare tumors with non-specific clinical presentations. The current case was unique since the tumor was first detected on endometrial curettage and clinicoradiologically was misdiagnosed as endometrial carcinoma.Case Report: A 48-year-old, ...  Read More

Gynecologic Pathology
Xanthogranulomatous Oophoritis: A Rare Case Report

Kaneeka Bhatnagar; Vikram Narang; Bhavna Garg; Neena Sood

Volume 13, Issue 3 , July 2018, , Pages 372-376

  Background and Objective: Xanthogranulomatous oophritis is an uncommon, non-neoplastic, chronic process in which the affected organ is destroyed by massive cellular infiltration of foamy histiocytes admixed with multinucleated giant cells, plasma cells, fibroblasts, neutrophils, and foci of necrosis. ...  Read More

Gynecologic Pathology
Hepatoid Variant of Yolk Sac Tumor of Both Ovaries With Widespread Intra-abdominal and Lung Metastasis: A Case Report

Srilatha Parampalli Srinivas; Archana Shivamurthy; Lakshmi Rao; Rajeshwari Gurumoorthy Bhat

Volume 13, Issue 2 , April 2018, , Pages 289-293


  Hepatoid variant of yolk sac tumor of ovary is an unusual tumor with an aggressive behavior. It is usually observed in young females, presents with abdominal complaints and is associated with raised α-fetoprotein (AFP) levels. It should be differentiated from other hepatoid tumors involving the ...  Read More

Gynecologic Pathology
Pseudopapillary and Macrofollicular Microscopic Growth Patterns in an Advanced Stage Ovarian Dysgerminoma: A Case Report

Fatemeh Nili; Niusha Noubari; Alireza Abdollahi

Volume 13, Issue 1 , January 2018, , Pages 94-98


  ysgerminoma is one of the two most common types of ovarian germ cell tumors. Providing accurate pathologic diagnosis and treatment planning, the prognosis is good even in advanced stages. Pathologic diagnosis is generally straightforward. In microscopic examination, the usual known growth patterns in ...  Read More

Gynecologic Pathology
Ovarian Small Cell Carcinoma: A Rare Case Report and Review of Literature

Savita Agarwal; Megha Ralli; Pinki Pandey; Shruti Singh

Volume 13, Issue 1 , January 2018, , Pages 99-102


  Ovarian small cell carcinoma is a rare and highly malignant tumor with poor prognosis. It usually presents in younger females with features of hypercalcemia. The exact histogenesis of the tumor is unclear and it may present as an undifferentiated tumor. In such cases, immunohistochemistry (IHC) plays ...  Read More