Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Phenotypic and Molecular Characterization of Carbapenems Resistant Escherichia coli Isolated from Patients with Urinary Tract Infections in Ardabil Province, Iran

Shabnam khavandi; Mohsen Arzanlou; Roghayeh Teimourpour; Hadi Peeridogaheh

Volume 17, Issue 3 , July 2022, , Pages 261-267


  Background & Objective: Carbapenem-resistant is Gram-negative bacteria representing a worldwide public health problem. The present study aims to survey the phenotypic and genotypic characteristics of carbapenem-resistant Escherichia coli isolates collected from hospitalized patients and outpatients ...  Read More

Anti-biofilm Activity of a Lytic Phage Against Vancomycin-Resistant Enterococcus faecalis

Forough Goodarzi; Masoumeh Hallajzadeh; Mohammad Sholeh; Malihe Talebi; Vahid Pirhajati Mahabadi; Nour Amirmozafari

Volume 17, Issue 3 , July 2022, , Pages 285-294


  Background & Objective: This study aims to isolate a lytic bacteriophage against planktonic Enterococcus faecalis V583 culture and evaluate its ability to disrupt and inhibit biofilm.Methods: An anti-E. faecalis phage was isolated from sewage and visualized by electron microscopy, the vB_EfsS_V583 ...  Read More

The Antibacterial and Anti-biofilm Traits of the Novel BMAP-27-Melittin Conjugated Peptide Nanoparticle Against Streptococcus mutans: Clinical Isolates from Oral Cavity

Mohammad Pourahmadi; Kimia Pourahmadi; Farzan Modaresi; Shekoufeh Atashpoor; Azita Azad; Alireza Ranjbaran; Abdolmajid Ghasemian

Volume 17, Issue 3 , July 2022, , Pages 294-302


  Background & Objective: The spread and development of drug-resistant bacterial strains has prompted the hunt for novel antibacterial polypeptides undergoing conformational changes to confer rapid bactericidal effects. The aim of this study was to evaluate the effect of novel BMAP27-Melittin conjugated ...  Read More

Evaluation of Triple Fragment Vaccine HSPX (Rv2031c) + PPE44 (Rv2770c) + Mouse IgG1 (Fcγ2a) with Auxiliary Adjuncts IL-22 in Comparison with BCG Vaccine

Azar valizadeh; Fra Khosravi; hamid sedighian; Elham Behzadi; Elaheh Parizad; Abbas Ali Imani Fooladi

Volume 17, Issue 3 , July 2022, , Pages 303-313


  Background & Objective: Despite the vaccination with the BCG vaccine, tuberculosis (TB) remains one of the major health problems in the world. The aim of this study was to evaluate our newly designed vaccine using IL-22 as an adjuvant in comparison with the common BCG vaccine.Methods: The gene constructs ...  Read More

The Epidemiological, Clinical, Mycological, and Pathological Features of Rhino-cerebral Mucormycosis: A Systematic Review

Mohammadreza Salehi; Shahram Mahmoudi; Omid Rezahosseini; Sayed Jamal Hashemi; Kazem Ahmadikia; Farzad Aala; Nasim Khajavirad; Neda Alijani; Alireza Izadi; Muhammad Ibrahim Getso; Alireza Abdollahi; Arezoo Salami; Seyedeh Rana Khatami; Alireza Adibimehr; Mojtaba Hedayat Yaghoobi; Mohammadmahdi Sabahi; Behshad Pazooki; Farhad Yazdi; Jayran Zebardast; Arash Seifi; Malihe Hasan Nezhad; Masoud Mardani; Sadegh Khodavaisy

Volume 17, Issue 2 , April 2022, , Pages 112-121


  Cerebral mucormycosis (CM) is a life-threatening manifestation of mucormycosis, an angioinvasive fungal infection caused by Mucorales. We sought to systematically review all available case reports to describe epidemiologic features, clinical manifestations, predisposing factors, and diagnostic and treatment ...  Read More

Higher Viral Load of Polyomavirus Type BK but not JC among Renal Transplant Recipients in Comparison to Donors

Samaneh Abolbashari; MohammadTaghi Shakeri; Maryam Hami; Aida Gholoobi; Amin Hooshyar Chechaklou; Mohammad Sadegh Damavandi; Aref Movaqar; Razieh Yousefi; Zahra Meshkat; Saeedeh Hajebi Khaniki

Volume 17, Issue 1 , January 2022, , Pages 8-14


  Background & Objective: Polyomaviruses types BK and JC and Cytomegalovirus (CMV) have been shown to be related to kidney transplantation complications. This study aimed to assess the prevalence of these viruses in patients receiving kidney transplantation.Methods: This cross-sectional study was performed ...  Read More

Changes of Routine Hematological Parameters in COVID-19 Patients: Correlation with Imaging Findings, RT-PCR and Outcome

Abdolreza Javadi; Shahriar Dabiri; Manzumeh Shamsi Meymandi; Mohammad Hashemi-Bahremani; Hussein Soleimantabar; Bahram Dabiri; Houman Vosough; Maryam Gheidi Sharan; Farnoosh Sedaghati

Volume 17, Issue 1 , January 2022, , Pages 37-47


  Background & Objective: Coronavirus disease 2019 (COVID-19) is progressively spreading, and many researchers have focused on the prognostic value of laboratory analyses. This study reviewed routine blood parameters, upper respiratory viral load, and chest imaging in recovered and expired COVID-19 ...  Read More

The Performance of SARS-CoV-2 Serology Testing in the Diagnosis of COVID-19

Alireza Abdollahi; Samaneh Salarvand; Vahid Mehrtash; Bita Jafarzadeh; Mohammadreza Salehi; Reza Ghalehtaki; Saeed Nateghi

Volume 17, Issue 1 , January 2022, , Pages 65-70


  Background & Objective: COVID-19 reverse transcription-polymerase chain reaction (RT-PCR) has been a reference test for diagnosing a disease since the very beginning of the pandemic. COVID-19 serology tests have also been developed and used to estimate the prevalence of individuals who have already ...  Read More

Is There A Correlation Between COVID-19 and Hepatitis A and Hepatitis E Serum Antibody Level?

Alireza Abdollahi; Samaneh Salarvand; Vahid Mehrtash; Bita Jafarzadeh; Reza Ghalehtaki; Saeed Nateghi

Volume 17, Issue 1 , January 2022, , Pages 71-74


  Background & Objective: The prevalence of COVID-19 and its severity have been observed to be on a lower level in underdeveloped countries with poorer standards of hygiene. This disparity may be attributed to the higher seroprevalence of other viral diseases which can result in the presence of antibodies ...  Read More

Molecular Characterization of Antibiotic Resistance Associated with TEM and CTX-M ESBL in Uropathogenic E. coli Strains Isolated from Outpatients

Sorour Farzi; Reza Ranjbar; Mohammad Niakan; Mohammad Hossein Ahmadi

Volume 16, Issue 4 , August 2021, , Pages 386-391


  Background & Objective: Escherichia coli (E. coli) is a leading cause of urinary tract infections becoming resistant against beta-lactams and cephalosporins through different mechanisms, including ESBL production due to the presence of ESBL specific genes, including blaCTX-M and blaTEM. The purpose ...  Read More

Evaluating of the Effects of Sub-MIC Concentrations of Gentamicin on Biofilm Formation in Clinical Isolates of Pseudomonas aeruginosa

Zahra Yousefpour; Fateme Davarzani; Parviz Owlia

Volume 16, Issue 4 , August 2021, , Pages 403-410


  Background & Objective: The ability of Pseudomonas aeruginosa to form biofilm has an important role in establishment of chronic phase of infections. Biofilm formation can be affected by antibiotics sub-MIC concentrations. The principal aim of the present study was to evaluate the effect of gentamicin ...  Read More

The role of Gene Mutations (gyrA, parC) in Resistance to Ciprofloxacin in Clinical Isolates of Pseudomonas Aeruginosa

Zoheir Heshmatipour; Nasibeh Arabameri; Shima Eftekhar Ardebili; Zeinab Jafari Bidhendi

Volume 16, Issue 4 , August 2021, , Pages 426-432


  Background & Objective: Pseudomonas aeruginosa is an opportunistic pathogen and one of the most common causes of nosocomial infections. This bacterium's antibiotic resistance to the common fluoroquinolone antibiotics, especially ciprofloxacin, is due to mutations in the gyrA and parC genes. This ...  Read More

COVID-19 Impact on Modern Virtual Pathology Education: Challenges and Opportunities

Seyed Esmaeil Azimi Khatibani; Shima Tabatabai

Volume 16, Issue 4 , August 2021, , Pages 439-443


  Background & Objective: Pathology education conventional methods have been disrupted by the Corona-Virus Disease 2019 (COVID-19) outbreak, compelling a re-evaluation of the means of educational interactions from the undergraduate to the postgraduate level. This commentary explores how the COVID-19 ...  Read More

The Bright Side of COVID-19: Integrated Art-based and Virtual Learning in Medical Education

Afsaneh Yakhforoshha; Fatemeh SamieeRad

Volume 16, Issue 3 , July 2021, , Pages 343-345


  This approach to learning is in accordance with the first of six strategies of Harden SPICES model for curriculum development: student-centered against teacher-centered approach (S) (7,8). In total, the results from medical students and the Knowles’ Andragogical Model as a theoretical lens, is ...  Read More

Concerning the Prevalence of HPV Genotypes and the Evaluation of Pap smear Results in Iranian Population: An Update

Sina Neshat; Padideh Daneii; Negar Neshat; Sina Raeisi; Saba Raeisi; Seyed Mohammad Malakooti; Noushin Afshar Moghadam

Volume 16, Issue 3 , July 2021, , Pages 346-347


  Human papillomavirus infection is one of the most common genital infections. More than 100 types of the virus have been identified, most of which can infect the genital mucosa. The virus is associated with cancerous and precancerous lesions of the cervix. Some types, such as human papillomavirus 16 and ...  Read More

Radiological and Laboratory Findings of Patients with COVID-19 Infection at the Time of Admission

Saeed Mirsadraee; Mihan Pourabdollah Toutkaboni; Mehrdad Bakhshayeshkaram; Mitra sadat Rezaei; Elham Askari; Sara Haseli; Nazanin Sadraee

Volume 16, Issue 2 , April 2021, , Pages 137-143


  Background & Objective: Diagnosis of coronavirus disease 2019 (COVID-19) can be challenging, especially when the real­time quantitative reverse transcription polymerase chain reaction (RT-PCR) is not available or it is negative. In this study, we evaluated imaging and laboratory findings in a ...  Read More

Serology Testing for SARS-CoV-2: Benefits and Challenges

Mohammadreza Jalali Nadoushan; Soha Ahmadi; Paniz Jalali Nadoushan

Volume 15, Issue 3 , July 2020, , Pages 154-155


  As COVID-19 was declared as a pandemic by the World Health Organization (WHO) in March 2020, it is an emerging need to discuss different aspects of this pandemic. In any pandemic, valid and rapid laboratory diagnostic tests are critically important for early diagnosis, which will increase the rate of ...  Read More

Evaluation of Phenotypic and Genotypic Characteristics of Carbapnemases-producing Enterobacteriaceae and Its Prevalence in a Referral Hospital in Tehran City

Kosar Jalalvand; Nasrin Shayanfar; Freshteh Shahcheraghi; Elahe Amini; Masha Mohammadpour; Pegah Babaheidarian

Volume 15, Issue 2 , April 2020, , Pages 86-95


  Background & Objective: Carbapenem-resistant Enterobacteriaceae is a growing concern worldwide including Iran. The emergence of this pathogen is worrying as carbapenem is one of the 'last-line' antibiotics for treatment of infections caused by multi drug resistant gram- negative bacteria. The main ...  Read More

Assessment of Susceptibility to Five Common Antibiotics and Their Resistance Pattern in Clinical Enterococcus Isolates

Sara Masoumi Zavaryani; Reza Mirnejad; Vahhab Piranfar; Mehrdad Moosazadeh Moghaddam; Nikta Sajjadi; Somayyeh Saeedi

Volume 15, Issue 2 , April 2020, , Pages 96-105


  Background & Objective: Enterococcus Species are the common cause of nosocomial infections, which are highly resistant to different antibiotics. Therefore, determination of their antibiotic susceptibility patterns and simultaneous resistance to antibiotics is important for better treatment strategies. ...  Read More

Persister cells formation and expression of type II Toxin-Antitoxin system genes in Brucella melitensis (16M) and Brucella abortus (B19)

Fatemeh Amraei; Negar Narimisa; Behroz Sadeghi; Vahid Lohrasbi; Faramarz Masjedian Jazi

Volume 15, Issue 2 , April 2020, , Pages 127-133


  Background & Objective: Persister cells are defined as a subpopulation of bacteria that are capable of reducing their metabolism and switching to dormancy in stress conditions. Persister cells formation has been attributed to numerous mechanisms, including stringent response and Toxin-Antitoxin (TA) ...  Read More

Molecular Characterization of Community-Associated Methicillin-Resistant Staphylococcus aureus in Iranian Burn Patients

Samira Tajik; Shahin Najar Peerayeh; Bita Bakhshi; Reza Golmohammadi

Volume 14, Issue 4 , October 2019, , Pages 284-289


  Background & Objective: Methicillin-resistant Staphylococcus aureus (MRSA) is reported as one of the important bacterial causes of burn wound infections. This study was carried out to investigate molecular characterization of community-associated MRSA (CA-MRSA) isolated from Iranian burn ...  Read More

Designing and Analyzing the Structure of DT-STXB Fusion Protein as an Anti-tumor Agent: An in Silico Approach

Zeynab Mohseni Moghadam; Raheleh Halabian; Hamid Sedighian; Elham Behzadi; Jafar Amani; Abbas ali Imani fooladi

Volume 14, Issue 4 , October 2019, , Pages 305-312


  Background & Objective: A main contest in chemotherapy is to obtain regulator above the biodistribution of cytotoxic drugs. The utmost promising strategy comprises of drugs coupled with a tumor-targeting bearer that results in wide cytotoxic activity and particular delivery. The B-subunit of Shiga ...  Read More

Association of Some High-Risk Mucosal Types of Human Papillomavirus with Cutaneous Squamous Cell Carcinoma in an Iranian Population

Hassan Ehteram; Mohaddeseh Sadat Mousavian; Tahereh Mazoochi; Tahereh Khamehchian; Mohammad Karimian

Volume 14, Issue 4 , October 2019, , Pages 313-316


  Background & Objective: Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer that may be caused by Human papillomavirus (HPV), especially in immunosuppressed patients. However, the role of the mucosal types of HPV in SCC patients with normal immunity has not been extensively ...  Read More

Molecular Characteristics of Methicillin-Resistant Staphylococcus aureus (MRSA) Isolated from Diabetic Foot Infection

Pegah Kananizadeh; Solmaz Ohadian Moghadam; Yasaman Sadeghi; Abbas Rahimi Foroushani; Hossein Adibi; Mohammad Reza Pourmand

Volume 14, Issue 4 , October 2019, , Pages 329-337


  Background & Objective: Diabetic foot ulcer (DFU), is one of the most frequent causes for hospitalizations in patients with diabetes. A major problem in the treatment of DFU is the increased-incidence of methicillin-resistant Staphylococcus aureus (MRSA). The aim of this study was to determine the ...  Read More

The Prevalence of HPV Genotypes in Iranian Population: An Update

Mina Mobini Kesheh; Hossein Keyvani

Volume 14, Issue 3 , August 2019, , Pages 197-205


  Background & Objective: Human papillomavirus (HPV) is the main cause of genital warts and some anogenital cancers in male and female subjects which is commonly transmitted by sexual contacts. The objective of this cross-sectional study was to examine the prevalence of HPV genotypes in 10,266 Iranian ...  Read More