Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Infectious Diseases
Effects of Human Nucleolus Upon Guest Viral-Life, Focusing in COVID-19 Infection: A Mini- Review

Moslem Bahadori; Mohammad Hossein Azizi; Shahriar Dabiri; Neda Bahadori

Volume 17, Issue 1 , January 2022, , Pages 1-7


  The nucleolus is a subcellular membraneless structure of eukaryotic cells. In 1965, in a world’s southern summer summit in Uruguay, the role of the nucleolus as the site of ribosome synthesis, biogenesis, and processing of tRNA was conclusively established. Today, accumulating evidence confirm ...  Read More

Biology & Genetic
Cytogenetic Study of Patients with Primary Amenorrhea in the Northeast of Iran

Narjes Soltani; Farzaneh Mirzaei; Hossein Ayatollahi

Volume 16, Issue 1 , January 2021, , Pages 57-61


  Background & Objective: Primary amenorrhea refers to the absence of menstruation in females of reproductive by age 16 when the development of secondary sexual characteristics is evident (breast development, pubic hair) or by age 14 when there are no secondary sexual characteristics are present. Primary ...  Read More

Biology & Genetic
Peer Review Publication Skills Matter for Academicians

Payam Behzadi

Volume 16, Issue 1 , January 2021, , Pages 95-96


  Dear EditorOn July 21 (Sunday) and 23 (Tuesday) 2019, I had an opportunity to hold another workshop titled “How to write a scientific paper?” for Ph.D. students in Microbiology Department, Basic Sciences Faculty, the Islamic Azad University, Shahr-e-Qods Branch, Tehran, Iran. I received brilliant ...  Read More

Biology & Genetic
Different Immune Responses in Dangerous O Blood Donors

shaghayegh Arabi; Mostafa Moghadam; Vida Maleki; Ali Akbar Pourfatholah; Afsaneh Aghaie

Volume 15, Issue 1 , January 2020, , Pages 34-40


  Background & Objective:Dangerous O is very important to transfusion medicine and there has been reports by Food and Drug Administration (FDA) regarding some death relating incidences. As high iso-antibody production is closely associated with different immune reactions, a survey on the different ...  Read More

Biology & Genetic
Cell-bound Exopolysaccharide Extract from Indigenous Probiotic Bacteria Induce Apoptosis in HT–29 cell-line

Parisa Mojibi; Farzaneh Tafvizi; Maryam Bikhof Torbati

Volume 14, Issue 1 , January 2019, , Pages 41-51


  Background and Objective: The aim of this study was to compare the cytotoxic effects of local probiotic bacteria, including Lactobacillus paracasei, Lactobacillus brevis, while isolated from “Tarkhine” food and the induction of apoptosis in the HT–29 human colon adenocarcinoma ...  Read More

Biology & Genetic
The Effect of Cadmium on Apoptotic Genes mRNA Expression of Bax and Bcl-2 in Small Intestine of Rats

Narjes Seid Alian; Parvin khodarahmi; Vahid Naseh

Volume 13, Issue 4 , October 2018, , Pages 408-414

  Background: Cadmium is a potent toxicant and carcinogenic in human and experimental animals. The evidence indicates that cadmium induces aberrant gene expression, inhibition of DNA damage repair, and apoptosis. In this study, we investigated the effects of IP (intraperitoneal) injection of cadmium on ...  Read More

Biology & Genetic
Relationship Between PIK3CA Amplification and P110α and CD34 Tissue Expression as Angiogenesis Markers in Iranian Women with Sporadic Breast Cancer

Shadi Hosseini; Farkhondeh Behjati; Maryam Rahimi; Nazanin Taheri; Hamid Reza Khorram Khorshid; Fatemehte Aghakhani Moghaddam; Saghar Ghasemi Frouzabadi; Masoud Karimlou; Fereidoon Sirati; Elahe Keyhani

Volume 13, Issue 4 , October 2018, , Pages 447-453

  Background and Objective: The PI3K/AKT/mTOR pathway is known to play an important role in regulating angiogenesis both in normal and breast cancer (BC) tissues. PIK3CA amplification was reported in various malignancies, including approximately 10% of BC cases. The aim of this study was to identify the ...  Read More

Biology & Genetic
A Review of Driver Genetic Alterations in Thyroid Cancers

Fatemeh Khatami; Mohammad Tavangar

Volume 13, Issue 2 , April 2018, , Pages 125-135


  Thyroid cancer is a frequent endocrine related malignancy with continuous increasing incidence. There has been moving development in understanding its molecular pathogenesis recently mainly through the explanation of the original role of several key signaling pathways and related molecular distributors. ...  Read More

Biology & Genetic
KRAS Codon 12 and 13 Mutations in Gastric Cancer in the Northeast Iran

Hossein Ayatollahi; Alireza Tavassoli; Amir Hossein Jafarian; Amin Alavi; Sepideh Shakeri; Seyyede Fatemeh Shams; Maryam Sheikhi; Neda Motamedi Rad; Mohammadhadi Sadeghian; Afsane Bahrami

Volume 13, Issue 2 , April 2018, , Pages 167-172


  Background & objective: KRAS mutations are reported in many types of cancers including pancreas, lung, colon, breast, and gastric (GC). High frequency of KRAS mutation is observed in the pancreas, colon, and lung cancers; they commonly arise in codon 12 and 13 of exon 2. Due to the lack of information ...  Read More

Biology & Genetic
The Association of Gastritis and Peptic Ulcer With Polymorphisms in the Inflammatory-related Genes IL-4 and IL-10 in Iranian Population

Meysam Rezaeishahmirzadi; Neda Motamedi Rad; Mehdi Kalantar; Hossein Ayatollahi; Sepideh shakeri; Maryam Sheikhi; Mohammad Shekari

Volume 13, Issue 2 , April 2018, , Pages 229-236


  Background and Objective: The current study aimed at assessing the relationship between gastritis and peptic ulcer susceptibility and inflammation-related gene polymorphisms in Iranian patients. Gastritis and peptic ulcer are common medical complications with serious outcomes on the quality of life. ...  Read More

Biology & Genetic
Classification and Biomarker Genes Selection for Cancer Gene Expression Data Using Random Forest

Malihe Ram; Ali Najafi; Mohammad Taghi Shakeri

Volume 12, Issue 4 , December 2017, , Pages 339-347


  Background & objective: Microarray and next generation sequencing (NGS) data are the important sources to find helpful molecular patterns. Also, the great number of gene expression data increases the challenge of how to identify the biomarkers associated with cancer. The random forest (RF) is used ...  Read More

Biology & Genetic
Differentiating and Categorizing of Liposarcoma and Synovial Sarcoma Neoplasms by Fluorescence in Situ Hybridization

Farhad Shahi; Razieh Alishahi; Hossein Pashaiefar; Isa Jahanzad; Naser Kamalian; Ardeshir Ghavamzadeh; Marjan Yaghmaie

Volume 12, Issue 3 , July 2017, , Pages 209-217


  Background & Objective: Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumors of mesenchymal origin and various cytogenetic abnormalities ranging from distinct genomic rearrangements, such as chromosomal translocations and amplifications, to more intricate rearrangements ...  Read More

Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction (ERIC-PCR) Genotyping of Escherichia coli Strains Isolated from Different Animal Stool Specimens

Reza Ranjbar; Afsar Tabatabaee; Payam Behzadi; Rohollah Kheiri

Volume 12, Issue 1 , January 2017, , Pages 25-34


  Background: Escherichia coli is a commensal-pathogenic organism, which includes a wide range of strains. Despite several advanced molecular-genomic technologies for detecting and identifying different strains of E. coli, Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction ...  Read More

Biology & Genetic
The Diagnosis of HIV Infection in Infants and Children

Alireza Abdollahi; Hana Saffar

Volume 11, Issue 2 , April 2016, , Pages 89-96

  It is estimated that the number of HIV infected children globally has increased from 1.6 million in 2001 to 3.3 million in 2012. The number of children below 15 years of age living with HIV has increased worldwide. Published data from recent studies confirmed dramatic survival benefit for infants started ...  Read More

Biology & Genetic
Maspin Gene Expression in Invasive Ductal Carcinoma of Breast

Shahriar Dabiri; Mohammadmehdi Moeini aghtaei; Jahanbano Shahryari; Manzume Shamis meymandi; Sahar Amirpour-Rostami; Reza Foutohi-Ardekani

Volume 11, Issue 2 , April 2016, , Pages 104-111

  Background: The breast cancer is the most prevalent cancer among women, on the other hand absence of myoepithelial cells play a pivotal role in pathogenesis of this cancer. Thus we aimed to investigate the possible abilities of the molecular assay technique to find a relationship between mammary serine ...  Read More