Iranian Journal of Pathology

Comparative Evaluation of Cell Block Method and Smear Cytology in Fine Needle Aspiration Cytology of Intra-abdominal Mass Lesions

Document Type : Original Research

Authors

Sourav Bhowmik 1
Indranil Chakrabarti 2
Piyali Ghosh 3
Pranati Bera 2
Tarak Banik 4

1 Dept Of Pathology, Ruby General Hospital, Kolkata, India

2 Dept Of Pathology, North Bengal Medical College, The West Bengal University Of Health Sciences, Siliguri, Darjeeling, India

3 Dept Of Pathology, Calcutta National Medical College, The West Bengal University Of Health Sciences, Kolkata, India

4 Dept Of Pathology, Malda Medical College, The West Bengal University Of Health Sciences, Malda, India

https://doi.org/10.30699/ijp.13.2.179
Abstract
Background& Objective: Fine needle aspiration cytology (FNAC) is an easy, rapid, and less hazardous tool to diagnose the intra-abdominal lesions with various imaging modalities adding to its sensitivity and accuracy. However, sometimes it does not yield adequate information for precise diagnosis and the risk of false-negative and indeterminate diagnosis is always present. Cellblock preparations may be particularly helpful in such problematic cases.
The current study aimed at evaluating and comparing the cytological as well as histopathological features of different intra-abdominal mass lesions.
Methods: Image-guided FNAC followed by cell block were performed on 167 patients from June 2012 to May 2013. Histologically correlated 111 cases were evaluated. Results of conventional smear, cell block, and combination of FNAC with cell block were compared with histopathological findings regarding diagnostic sensitivity, specificity, and accuracy of diagnosis.
Result: Cell block was more specific to diagnose these lesions than FNAC (95.49% versus 90.09%). Combined application of cell block with FNAC was more specific (96.39%) than cell block alone with 100% diagnostic accuracy.
Conclusion: Application of a combination of cell block with FNAC was more useful to diagnose intra-abdominal mass lesions.

Keywords

Intra-abdominal Mass
Fine needle aspiration cytology
Cell Block
Iranian Journal of Pathology
Volume 13, Issue 2
Spring 2018
Pages 179-187

  • Receive Date 29 October 2016
  • Revise Date 13 June 2017
  • Accept Date 05 April 2018

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