Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Review Article
Malignant Colorectal Polyps; Pathological Consideration (A review)

Bita Geramizadeh; Mahsa Marzban; David Owen

Volume 12, Issue 1 , January 2017, Pages 1-8


  Background: Routine screening colonoscopy is on the rise and pathologists have to deal with the ever larger numbers of excised colonic polyps. It is very important to optimize the patients’ individual treatment and further surveillance. Pathologists play a critical role in management, as most of ...  Read More

Original Research
Evaluation of Immunohistochemistry-Equivocal (2+) HER2 Gene Status in Invasive Breast Cancer by Silver DNA in Situ Hybridization (SISH) and its Association with Clinicopathological Variables

Zaidoon A. Musa; Ban J. Qasim; A.Wahab A.K. Al Shaikhly

Volume 12, Issue 1 , January 2017, Pages 9-19


  Background and Objective:Determination of HER2 gene is crucial in breast carcinoma management and prognosis, as HER2 alterations are linked to a shorter disease-free period, overall survival and resistance to tamoxifen anti-estrogen therapy and other chemotherapy regimens, regardless of the nodal or ...  Read More

Original Research Hematopathology
Aggressive Fibromatosis, Clinicopathologic Findings of 25 Cases; A Single-Center Experience and Review of the Literature

Bita Geramizadeh; Fatemeh Jalali

Volume 12, Issue 1 , January 2017, Pages 20-24


  Background: Aggressive fibromatosis is a rare benign tumor with no potential for metastasis; however, its aggressive nature causes treatment failure and episodes of recurrence. There is no report from Iran about the treatment of this tumor, and all published articles are single-case reports, therefore ...  Read More

Original Research Microbiology
Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction (ERIC-PCR) Genotyping of Escherichia coli Strains Isolated from Different Animal Stool Specimens

Reza Ranjbar; Afsar Tabatabaee; Payam Behzadi; Rohollah Kheiri

Volume 12, Issue 1 , January 2017, Pages 25-34


  Background: Escherichia coli is a commensal-pathogenic organism, which includes a wide range of strains. Despite several advanced molecular-genomic technologies for detecting and identifying different strains of E. coli, Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction ...  Read More

Original Research
Cervical Cancer and Genital Infections: Assessment of Performance and Validation in Human Papillomavirus Genotyping Assays in Iran, its Neighbouring Countries and Persian Gulf Area

Amir Sohrabi; Massoud Hajia

Volume 12, Issue 1 , January 2017, Pages 35-44


  Background: The accuracy of diagnostic assays in Human Papillomavirus (HPV) genital infection and cervical cancer has remained a clinical challenge in diagnosis.  Evidence indicates that a large proportion of cervical cancer can be prevented through organized care for HPV and testing. Countries ...  Read More

Original Research
Immunohistochemical and Electron Microscopic Study of the Inhibitory Effects of Olive Oil Polyphenol on Dexamethasone-Induced Apoptosis

Ali Reza Khalatbary; Behrooz Mohammadnegad; Ghazaleh Goudarzi; Ali Fazlollahpour Balef

Volume 12, Issue 1 , January 2017, Pages 45-52


  Background: There is accumulating evidence that a polyphenol present in olive oil, oleuropein, has antioxidant, anti-inflammatory and anti-apoptotic effects. This study aimed at determining the anti-apoptotic effect of Oleuropein (Ole) on dexamethasone-induced apoptosis of mouse thymocytes. Method: Mice ...  Read More

Original Research Microbiology
Investigation of Efflux-Mediated Tetracycline Resistance in Shigella Isolates Using the Inhibitor and Real Time Polymerase Chain Reaction Method

Shadi Shahsavan; Parviz Owlia; Abdolaziz Rastegar Lari; Bita Bakhshi; Maliheh Nobakht

Volume 12, Issue 1 , January 2017, Pages 53-61


  Background: Shigella spp. are gram negative bacteria, which are of global public health importance. The growing of multidrug-resistant Shigella isolates are a major problemaround the world. Methods: Overall, 50 isolates of Shigella spp. from children diarrheic stools were studied. ...  Read More

Original Research Dermatopathology
Comparison of P53 Intensity, Frequency and Size in Normal Skin Periphery of Squamous Cell Carcinoma, Basal Cell Carcinoma And Melanocytic Nevus in Persian Skin Type

Farahnaz Bidari Zerehpoosh; Soheila Nasiri; Sara Zahedifard; Shahram Sabeti

Volume 12, Issue 1 , January 2017, Pages 62-66


  Background:Non-Melanoma Skin Cancer (NMSC), the most prevalent types being Squamous Cell Carcinoma (SCC) and Basal Cell Carcinoma (BCC), is the most common type of malignancy in human beings. These neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites ...  Read More

Original Research Hematopathology
Fluorescent in Situ Hybridization and Real-Time Quantitative Polymerase Chain Reaction to Evaluate HER-2/neu Status in Breast Cancer

Fatemeh Homaei Shandiz; Azar Fani; Sepideh Shakeri; Maryam Sheikhi; Abouzar Ramezani Farkhani; Arezoo Shajiei; Hossein Ayatollahi

Volume 12, Issue 1 , January 2017, Pages 67-73


  Background:Breast cancer remains the most common and second lethal cancer in females. HER-2/neu is one of the most important amplified oncogene in breast cancer. The amplification of HER-2 is correlated with decreased survival, metastasis, and early recurrence.  The amplification of HER-2/neu gene ...  Read More

Original Research
Alpha-Synuclein Expression in Acute Erythroleukaemia, Acute Megakaryoblastic Leukemia, and Normal Counterparts in Bone Marrow

Farid Kosari; Sanam Akbarzadeh; Hiva Saffar

Volume 12, Issue 1 , January 2017, Pages 74-78


  Background:Alpha-synuclein is a member of synuclein family of proteins with unidentified function localized in the cytoplasm, mitochondria of neurons, and presynaptic nerve endings. Although it is found in the Lewy bodies in synucleinopathies and in Alzheimer’s disease, the protein could also be ...  Read More

Original Research Microbiology
Inhibitory activities of platelet-rich and platelet-poor plasma on the growth- of pathogenic bacteria

Omid Maghsoudi; Reza Ranjbar; Seyyed Hesamoddin Mirjalili; Mahdi Fasihi Ramandi

Volume 12, Issue 1 , January 2017, Pages 79-87


  Background:The utility and efficacy of novel materials in tissue regeneration and antimicrobial therapy are contingent upon the employment of either blood derivatives rich in platelets or platelet-poor-plasma (PPP). This effect is largely mediated by the increased or decreased concentration of platelets ...  Read More

Original Research Biochemistry
Upper Normal Limit of Thyroid-Stimulating Hormone and Metabolic Syndrome in Iranian Patients with Obesity

Zohreh Nozarian; Alireza Abdollahi; Vahid Mehrtash; Hirbod Nasiri Bonaki

Volume 12, Issue 1 , January 2017, Pages 88-93


  Background:The current study aimed at evaluating the association between thyroid-stimulating hormone (TSH) level in upper normal limits with metabolic syndrome, modifiable risk factor for cardiovascular disease, and its components according to Adult Treatment Panel III of National Cholesterol Education ...  Read More