Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Original Research
The Relationship between Cytokeratins 7 and 20 Expression, and Prognostic Factors in Colon Adenocarcinoma: An Immunohistochemical Study

Mohammad Hossein Gheini; Noushin Jalayer Naderi

Volume 12, Issue 2 , April 2017, Pages 94-98


  Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. ...  Read More

Original Research GI, Liver & Pancreas Pathology
Clinical Manifestations and Diagnosis of Non-Alcoholic Fatty Liver Disease

Mahmoodreza Khoonsari; Mohammadreza Mohammad Hosseini Azar; Ramak Ghavam; Khadijeh Hatami; Mosa Asobar; Ali Gholami; Abdolhalim Rajabi; Fahimeh Safarnezhad Tameshkel; Bahare Amirkalali; Masoudreza Sohrabi

Volume 12, Issue 2 , April 2017, Pages 99-105


  Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic ...  Read More

Original Research
Correlation Between Subclinical Hypothyroidism and Dyslipidemia

Alireza Rastgooye Haghi; Mahdis Solhjoo; Mohammad Hossein Tavakoli

Volume 12, Issue 2 , April 2017, Pages 106-111


  Background & Objective: Thyroid hormones have an important role in the regulation of lipid metabolism. Subclinical hypothyroidism (SCH), defined as a mild increase in thyroid-stimulating hormone (TSH) and normal level of thyroxine (T4), could be associated with altered lipid profile. The current ...  Read More

Original Research
Platelet Septic Transfusion Reactions in Patients With Hemato-Oncological Diseases

Farhad Razjou; Abolfazl Dabir Moghaddam; Gharib Karimi; Maryam Zadsar

Volume 12, Issue 2 , April 2017, Pages 112-118


  Background & Objective: Bacterial, contamination of blood components are a significant risk for transfusion reactions. Inherently, platelet concentrates (PCs) are vulnerable to bacterial contamination, due to the storage condition of processed PCs at room temperature, which provide very suitable ...  Read More

Original Research
Possible Interrelationship of Inflammatory Cells in Dry Type Cutaneous leishmaniasis

Elham Taheri; Shahriar dabiri; Manzoomeh Shamsi Meymandi; Ebrahim Saedi

Volume 12, Issue 2 , April 2017, Pages 119-127


  Background & Objective: There is a complicated interaction between leishmaniasis and the host immune cells, and also between the host immune cells. These interactions have fundamental effects on the outcome of the disease. The current study aimed at characterizing the number, distribution, co-localization, ...  Read More

Original Research Hematopathology
Chromogenic in situ Hybridization Compared with Real Time Quantitative Polymerase Chain Reaction to Evaluate HER2/neu Status in Breast Cancer

Hossein Ayatollahi; Azar Fani; Ehsan Ghayoor Karimiani; Fateme Homaee; Arezoo Shajiei; Maryam Sheikh; Sepideh Shakeri; Seyyede Fatemeh Shams

Volume 12, Issue 2 , April 2017, Pages 128-134


  Background and objective: The assessment of human epidermal growth factor receptor 2 (HER2) status has become of great importance in the diagnosis of breast cancer. The aim of this study was to investigate the diagnostic value of quantitative Polymerase Chain Reaction (qPCR) and Chromogenic In Situ Hybridization ...  Read More

Original Research Biochemistry
Effect of Silibinin on Maspin and ERα Gene Expression in MCF-7 Human Breast Cancer Cell Line

Maryam Karimi; Hossein Babaahmadi-Rezaei; Ghorban Mohammadzadeh; Mohammad-Ali Ghaffari

Volume 12, Issue 2 , April 2017, Pages 135-143


  Background and objective: According to reports, a serine protease inhibitor (Maspin) suppresses metastasis, invasion and angiogenesis in breast and prostate cancers. Silibinin is a natural polyphenolic flavonoid with anti-cancer activity. We assessed the effects of silibinin on cell viability, maspin ...  Read More

Original Research
The Prevalence of Human Papilloma Virus in Squamous Cell Carcinoma of Oral Tongue

Mohamad Javad Ashraf; Shahla Hosseini; Ahmad Monabati; Behnaz Valibeigi; Bijan Khademi; Elham Abedi; Negar Azarpira

Volume 12, Issue 2 , April 2017, Pages 144-149


  Background and objective:  Oral tongue Squamous Cell carcinoma (SCC) commonly involves males between the sixth to eighth decades of life. Major risk factors are tobacco usage and alcohol consumption. The increasing number of patients developing oral tongue cancer without these well-known risk factors ...  Read More

Original Research
Evaluation of Nuclear Morphometry and Ki-67 Index in Clear Cell Renal Cell Carcinomas: a Five‌-Year Study

Sheela devi C S; Suchitha Satish; Veerendrasagar Sahukar

Volume 12, Issue 2 , April 2017, Pages 150-157


  Background and objective: Clear Cell Renal Cell Carcinoma (CCRCC) is the most common adult renal neoplasm. Staging and grading of RCC are important predictors of survival. Fuhrman nuclear grading is widely used for CCRCC, the subjective nature of which has prompted more objective methods to evaluate ...  Read More

Original Research Gynecologic Pathology
The HER-2 as a Target Gene of Curcumin to Protect Hepatocytes Against the Arsenic-induced Carcinoma in Mice

Mahdi Ahadi; Vahid Naseh; Masoud Salehipour

Volume 12, Issue 2 , April 2017, Pages 158-164


  Background & objective: The HER-2 gene is an important on co protein overexpressed in many types of cancers. The current study hypothesized that curcumin downregulates HER-2 and inhibits the signal transduction pathway of PI3K/Akt, MAPK, and activation of NFκB, which could be useful to treat ...  Read More

Original Research Microbiology
Conserved OprF as a Selective Immunogen Against Pseudomonas aeruginosa

Ehsan Kazemi Moghaddam; Parviz Owlia; Abolfazl Jahangiri; Iraj Rasooli; Mohammad Reza Rahbar; Marjan Aghajani

Volume 12, Issue 2 , April 2017, Pages 165-170


  Background & Objectives: Due to the importance of Pseudomonas aeruginosa in severe inpatient infections and high mortality, the need for an efficient vaccine against these bacteria is increasing. In this regard, the general outer membrane porin of the most problematic microorganism P. aeruginosa, ...  Read More

Original Research Uropathology
Endothelin-1 expression in prostate needle biopsy specimens correlated with aggressiveness of prostatic cancer

Mojgan Asgari; Elham Eftekhar; Maryam Abolhasani; Hossein Shahrokh

Volume 12, Issue 2 , April 2017, Pages 171-176


  Background & Objective: As the prostate adenocarcinoma is one of the most common malignant tumors in males, looking for a marker to effectively predict aggressiveness and metastatic potential in an apparently localized cancer in initial needle biopsy specimens can help the clinicians to make more ...  Read More

Short Communication
Testicular Biopsy in Males With Infertility: A Longitudinal Study

Sepideh Siadati; Hamid Shafi; Hossein Ghorbani

Volume 12, Issue 2 , April 2017, Pages 177-182


  Background & objective: Regarding the importance of histologic examination of testicular biopsy for clinical planning of infertility, the current study was conducted to compare 2 separate histologic examination of testicular biopsy. Also, some cases with known fertility outcome were followed and ...  Read More

Short Communication
Sero-prevalence of Helicobacter pylori Infection in Neyshabur, Iran, During 2010-2015

Mohammad Salehi; Abdolmajid Ghasemian; Seyyed Khalil Shokouhi Mostafavi; Somayyeh Najafi; Hassan Rajabi Vardanjani

Volume 12, Issue 2 , April 2017, Pages 183-188


  Backgrounds & Objective: The Helicobacter pylori prevalence has continuously decreased during recent years in Iran. The current study aimed at determining H. pylori prevalence in Neyshabur city, Northeast Iran, during 2010-2015. Methods: The current epidemiologic survey was conducted in Neyshabur ...  Read More