Volume 19 (2024)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Review Article Biochemistry
Biomarkers for Assessment of Human Immunodeficiency Virus and its Co-Infection with Hepatitis B and Hepatitis C Viruses: A Comprehensive Review

Mohammad Abdi; Abbas Ahmadi; Aram Mokarizadeh

Volume 18, Issue 3 , July 2023, Pages 230-243


  Recently, prevalence of hepatitis B virus (HBV), and hepatitis C virus (HCV) co-infection with Human immunodeficiency virus (HIV), has dramatically increased worldwide due to their shared routes of transmission. Compared to sporadic infection with HIV, HBV, and HCV, concurrent infection with these agents ...  Read More

Review Article Infectious Diseases
Molecular Diagnosis of COVID-19; Biosafety and Pre-analytical Recommendations

Mohammad Vasei; Elham Jafari; Vahid Falah Azad; Moeinadin Safavi; Maryam Sotoudeh

Volume 18, Issue 3 , July 2023, Pages 244-256


  From the beginning of the COVID-19 epidemic, clinical laboratories around the world have been involved with tests for detection of SARS-CoV-2. Currently, RT-PCR (real-time reverse transcription polymerase chain reaction assay) is the gold standard for identifying the virus. Many factors are involved ...  Read More

Systematic Review Uropathology
Diagnostic Significance of Cytokeratin 20 and p53 as Adjunct Immunocytological Markers in Urine Cytology to Detect Urothelial Carcinomas: A Systematic Review Study

Evelyn - Angel

Volume 18, Issue 3 , July 2023, Pages 257-269


  The progression and recurrence of urothelial carcinoma (UC) are correlated with carcinoma in situ and urothelial dysplasia. It is frequently challenging to distinguish dysplasia and carcinoma in situ from reactive atypia only based on histological characteristics. In daily practices, 2 of the adjunct ...  Read More

Original Research Hematopathology
Hematocytological Clues of Peripheral Blood in Different Clinical Presentations of COVID-19

Fakhri Mohaghegh Zahed; Shahriar Dabiri; Abdolreza Javadi; Sajjadeh Movahedinia; Manzumeh Shamsi Meymandi Pharm; Bahram Dabiri; Parisa khorasani Esmaili; Mitra Sadat Rezaei; Mehrdad Farokhniya

Volume 18, Issue 3 , July 2023, Pages 270-278


  Background: To gain insight into the pathogenesis and clinical course of COVID-19 from a historical perspective, we reviewed paraclinical diagnostic tools of this disease and prioritized the patients with a more severe form of disease admitted to intensive care units (ICUs). The objective was to better ...  Read More

Original Research Neuropathology
Evaluation of INI1 Protein Expression Through IHC Study in Pediatric High-Grade Brain Tumors in South of Iran in 2008-2021

Maryam Mohebbi; Mansoureh Shokripour; Maral Mokhtari

Volume 18, Issue 3 , July 2023, Pages 279-288


  Background & Objective: Brain tumors are the most frequent solid tumors in children. High-grade tumors are more challenging in diagnosis. Atypical teratoid rhabdoid tumor (ATRT) may be mistaken for other high-grade brain tumors. Molecular genetic analysis of ATRT has shown deletion and mutation in ...  Read More

Original Research Infectious Diseases
Comparative Analysis of 198 SARS-CoV-2 Genomes from Iran and West Asia, February 2020 to December 2021

saman karami; Marziyeh Mojbafan; Ramin Mazaheri Nezhad Fard

Volume 18, Issue 3 , July 2023, Pages 289-298


  Background & Objective: Coronavirus disease 2019 (COVID‐19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in a worldwide pandemic. The first case of COVID‐19 was reported from Wuhan in the Hubei Province of China in December 2019; however, the disease's ...  Read More

Original Research GI, Liver & Pancreas Pathology
Evaluation of Circulating Leptin and Its Receptor (Ob-R) Tissue Expression in Colorectal Cancer, a Report From North of Iran

Masoume Mahmoudi-Nesheli; Reza Alizadeh-Navaei; Laleh Vahedi; Omolbanin Amjadi; Tarang Taghvaei; Iradj Maleki; Ramin Shekarriz; Arash Kazemi; Versa Omrani-Nava; Maryam Alizadeh-Forutan

Volume 18, Issue 3 , July 2023, Pages 299-305


  Background & Objective: Leptin is an adipocyte-derived hormone with a critical role in energy balance. As demonstrated by previous investigations, leptin acts as a proliferative and angiogenic factor in cancer cells. However, results regarding its role in colorectal cancer are still inconclusive. ...  Read More

Original Research Uropathology
The Prevalence of p16 Expression in Urothelial Bladder Cancer in a Tertiary Care Hospital of Chattogram, Bangladesh

Taniza Farnaz; Pradip Bhattacharjee; M. Shahab Uddin Ahamad; Sharmin Ashraf Rima; Naznin Nahar Momin; Anika Sadaf

Volume 18, Issue 3 , July 2023, Pages 306-311


  Background & Objective: p16 is a tumor suppressor gene, loss of which is usually associated with poor epithelial differentiation, resulting in tumor progression, which correlates with aggressive clinical behavior and poor prognosis. CDK 4/6 inhibitors can be used as a therapeutic target in p16 negative ...  Read More

Original Research Gynecologic Pathology
The Association Between Higher Expression of Talin-1 and the Reduced Survival Rate in Ovarian Serous Carcinoma Patients

Mina Sharbatoghli; Leili Saeednejad Zanjani; Fahimeh Fattahi; Elham Kalantari; Zohre Habibi Shams; Mahshid Panahi; Mehdi Totonchi; Mohsen Asadi-Lari; Zahra Majd

Volume 18, Issue 3 , July 2023, Pages 312-326


  Background & Objective: Talin-1 is a constituent of the multiprotein adhesion complexes that play  main role in the formation of tumors and migration in different types of malignancies. The present study aimed to assess  expression and prognostic significance of the talin-1 protein in ovarian ...  Read More

Original Research Hematopathology
P53 IHC Result as a Prognostic Tool in MDS

Alireza Rezvani; Ahmad Monabati; Zahra Kargar; Akbar Safaie; Mahdi Mahmoodzadeh; Hamideh Moosapour; Marzieh Hosseini; Soleiman Kheiri; Elham Taheri

Volume 18, Issue 3 , July 2023, Pages 327-334


  Background & Objective: Some of the patients with myelodysplastic syndrome (MDS) are categorized as good prognosis based on the Revised International Prognostic Scoring System (IPSS-R). However, these patients may have poor clinical outcomes. It seems that the current diagnostic tools and IPSS-R ...  Read More

Original Research Breast Pathology
Utility of Indigenously Developed Square Grid Method for Evaluation of Tumor-Stroma Ratio and Stromal Tumor-Infiltrating Lymphocytes in Invasive Breast Carcinoma: A Pilot Study


Volume 18, Issue 3 , July 2023, Pages 335-346


  Background & Objective: Invasive breast carcinoma (IBC) is the most commonly diagnosed cancer among women in India. The conventional visual method of evaluation of Tumor-Stroma Ratio (TSR) and Stromal Tumor-Infiltrating Lymphocytes (sTIL) appears to be subjective. The present study aims to evaluate ...  Read More

Original Research Infectious Diseases
Evaluation of Laboratory Findings of Patients with Coronavirus Disease 2019 in Kerman, Iran

Parisa Khorasani Esmaili; Shahriar Dabiri; Sajjadeh Movahedinia; Saeedeh Shojaeepour; Fatemeh Bagheri; Hanie Ranjbar; Manzumeh Shamsi Meymandi; Elham Mohebi; Mehrdad Farokhniya

Volume 18, Issue 3 , July 2023, Pages 347-355


  Background & Objective: Since December 2019 in Wuhan, China there is a new form of pneumonia and after expansion in other countries, World Health Organization (WHO) called it Coronavirus Disease 2019 (COVID-19). Since the clinical laboratory findings have played an important role in the progression ...  Read More

Original Research Microbiology
Simultaneous Genetically Detection of Streptococcus pyogenes, Streptococcus pneumoniae and Haemophilus influenzae in Patients with Treatment-Resistant Respiratory Infection

Farzad Mohammadi Ebli; Zoheir Heshmatipour; Khadijeh Daneshjou; Seyed Davood Siadat

Volume 18, Issue 3 , July 2023, Pages 356-362


  Background & Objective: Streptococcus pneumoniae, Haemophilus influenzae and Streptococcus pyogenes are among the most important causes of infection in human. Inventing rapid methods to identify these species can help in providing appropriate and effective treatment options. Therefore, the current ...  Read More

Original Research Uropathology
Evaluation of Cytokeratin-7 and Cytokeratin-19 Expression Relationship with Gleason Score in Prostatic Adenocarcinoma

Masood Soltanipur; Mohammadreza Jalali Nadoushan; Hossein Yarmohammadi

Volume 18, Issue 3 , July 2023, Pages 363-369


  Background & Objective: Prostatic adenocarcinoma (PAC) is one of the most common tumors worldwide. Immunohistochemical expression of cytokeratins has been evaluated in the diagnosis and prognosis of tumors. The aim of the present study is the evaluation of Cytokeratin-7 (Ck-7) and Cytokeratin-19 ...  Read More

Short Communication Endocrine Pathology
Investigation of Parvovirus B19, Cytomegalovirus, Herpes Simplex Virus Types 1 and 2, Human Papillomavirus Types 16 and 18 in Papillary Thyroid Carcinoma

Fakhrieh Kalavari; Parin Tanzifi; Tahereh Yosefi; Maryam Lotfi; Elham Nazar

Volume 18, Issue 3 , July 2023, Pages 370-375


  Background & Objective: Viral infections are associated with the pathogenesis and progression of human malignancies. Several studies have suggested the role of viral infections in papillary thyroid carcinoma (PTC). However, the results are still conflicting, and the potential role of viruses in PTC ...  Read More

Case Reports Head and Neck Pathology
Advanced Sinonasal Malignant Melanoma; A Case Report

Parisa Khorasani Esmaili; Shahriar Dabiri; Ayeh Shamsadini; Tooraj Reza Mirshekari

Volume 18, Issue 3 , July 2023, Pages 376-379


  Malignant melanoma of the sinonasal area is a rare tumor that arises from melanocytes in the nasal mucosa and is more aggressive than the cutaneous type with a poor prognosis.We report a 60-year-old female with the initial chief complaint of nasal cavity fullness, continuous epistaxis, and nasal bone ...  Read More