Infectious Diseases
Sedigheh Hantoushzadeh; Roya Saeednejad; Mamak Shariat; Raheleh Moradi
Abstract
Background & Objective: It was declared that COVID-19 might be more severe in symptomatic pregnant patients. This study was conducted to examine the pathological indices of the placenta in pregnant women who were diagnosed with COVID-19.Methods: A total of 20 COVID-19–positive mothers were ...
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Background & Objective: It was declared that COVID-19 might be more severe in symptomatic pregnant patients. This study was conducted to examine the pathological indices of the placenta in pregnant women who were diagnosed with COVID-19.Methods: A total of 20 COVID-19–positive mothers were enrolled in this study. Detailed placental pathology findings were compared between subjects based on the history of abortion or occurrence of preterm delivery, hypertension, and diabetes.Results and Conclusion: Intervillositis was the most frequent abnormality of the placenta. There was also a significant association between abortion history and maternal vascular malperfusion (MVM; P=0.02). The placental abnormalities were found to be increased in women with COVID-19, regardless of maternal comorbidities. Further studies are needed to compare the placental pathology between COVID-19–positive women and healthy women.
Gynecologic Pathology
Arshia Yazdani; Mohammad Ranaee; Sara Babazadeh; Fatemeh Shafizadeh
Abstract
Placental mesenchymal dysplasia (PMD) is an uncommon placental lesion, which may mimic molar pregnancy at gross and microscopic examination. PMD can be associated with fetal growth restriction, Beckwith-Wiedemann syndrome, intrauterine fetal death, and preterm delivery. Nonetheless, it may also be associated ...
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Placental mesenchymal dysplasia (PMD) is an uncommon placental lesion, which may mimic molar pregnancy at gross and microscopic examination. PMD can be associated with fetal growth restriction, Beckwith-Wiedemann syndrome, intrauterine fetal death, and preterm delivery. Nonetheless, it may also be associated with a normal appearing fetus.Objective: We aimed to emphasize that clinicians, radiologists, and pathologists should be aware of PMD as one of the etiologies of intrauterine growth restriction (IUGR).We presented the case of a 27-year-old gravida 1, para 1 woman who was admitted to Ayatollah Rouhani hospital, in Babol, Iran, at 30 weeks of gestation due to severe IUGR and fetal tachycardia. Ultrasound examination showed uteroplacental insufficiency and increased resistive index (RI) of umbilical artery. At last, a normal female fetus (1320 g) with no definitive anomalies was delivered by cesarean section. Pathological examination revealed cystically dilated stem villi with peripherally located thick-walled muscular stem vessels, and also stromal fibroblasts overgrowth in some stem villi. None of the examined sections revealed trophoblastic proliferation or stromal trophoblastic inclusion. The findings confirmed the diagnosis of PMD.Careful radiological and pathological examination should be performed in the case of IUGR for ruling out the rare placental abnormalities, including PMD.
Jawahar Ramasamy; Renu G’Boy Varghese
Volume 8, Issue 4 , October 2013, , Pages 263-266
Abstract
Pedunculated chorangioma is extremely rare type of chorangioma. To the best of our knowledge, no case has been reported in Indian literature. We report one such rare case in a twenty two year old primi gravida who delivered a full term live female baby by lower section caesarian section (LSCS). Gross ...
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Pedunculated chorangioma is extremely rare type of chorangioma. To the best of our knowledge, no case has been reported in Indian literature. We report one such rare case in a twenty two year old primi gravida who delivered a full term live female baby by lower section caesarian section (LSCS). Gross examination revealed a nodular mass attached to the placenta by a pedicle. Histopathological examination confirmed it as chorangioma. The clinicopathological and radiological feature of this rare entity is presented with a brief review of literature.
