Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Number of Volumes 15
Number of Issues 61
Number of Articles 767
Number of Contributors 2,391
View Per Article 1452.2
PDF Download Per Article 868.12
Number of Submissions 1,500
Number of Indexing Databases 48
Number of Reviewers 533

Iranian Journal of Pathology (Iran J Pathol)

Quarterly Journal of Anatomical and Clinical Pathology

The IRANIAN JOURNAL OF PATHOLOGY (IJP),  is an international journal and publishes original research papers, reviews, case  reports, short communications and letters to editor with priority for  high quality original papers on mechanisms of disease and clinical trials. We accept manuscripts that report important findings  on disease pathogenesis and basic biological mechanisms that relate to disease without preferences for a  specific method of analysis. High priority is given to  studies on human diseases and relevant experimental models that use cellular, molecular, biochemical & immunological approaches in conjunction with morphology, and to manuscripts that report new diagnostic methods or analytical systems and their application in studies of disease pathogenesis and diagnosis.   

 

  • Bone and Soft Tissue Pathology,
  • Dermatopathology,
  • Biochemistry,
  • Biology & Genetic,
  • Infectious Diseases,
  • Microbiology,
  • GI pathology & Hepatopathology,
  • Endocrine Pathology,
  • ENT & Ophthalmic Pathology,
  • Gynecologic & Breast Pathology,
  • Molecular Pathology,
  • Nephropathology,
  • Neuropathology,
  • Neuroscience and Anatomy,
  • Oncology & Hematology,
  • Oral Pathology,
  • Pediatric Pathology,
  • Surgical Pathology,
  • Diagnostic Pathology,
  • Uropathology

 

             

 

Editorial Hematopathology
1. The changes of Coagulation State in Patients Contracted with SARS-COV-19

Anahita Nosrati

Volume 15, Issue 4 , Autumn 2020, Pages 259-260

http://dx.doi.org/10.30699/ijp.2020.129354.2427

Abstract
  Coronaviruses are considered to be one of the most significant human and animal pathogens. In late 2019, a new species of coronavirus was recognized as the cause of some pneumonia cases in Wuhan, China. The disease spread rapidly and made an epidemic in China and subsequently in almost all countries ...  Read More

Original Research Biochemistry
2. Clinical Validation of Eleven Formulas for Calculating LDL-C in Iran

Fereshteh Atabi; Reza Mohammadi

Volume 15, Issue 4 , Autumn 2020, Pages 261-267

http://dx.doi.org/10.30699/ijp.2020.110379.2174

Abstract
  Background & Objective: Concentration of low-density lipoprotein (LDL) is a known risk factor for cardiovascular disease which is routinely measured or calculated as LDL-C in clinical laboratories. In order to decrease the cost, instead of its measuring, it is recommended to calculate it using multiple ...  Read More

Original Research GI, Liver & Pancreas Pathology
3. Assessment of p16 and Ki67 Immunohistochemistry Expression in Squamous Intraepithelial Lesion with Cytohistomorphological Correlation

Apurv Ghosh; M Nirupama; Nandan Padmanabha; Hema Kini

Volume 15, Issue 4 , Autumn 2020, Pages 268-273

http://dx.doi.org/10.30699/ijp.2020.112421.2208

Abstract
  Background & Objective: Cervical cancer is the most common cancer in women worldwide with high mortality, necessitating quicker diagnostic methods. We wish to enhance the existing cervical biopsies of Squamous Intraepithelial Lesions (SIL) using p16 and Ki67 as surrogate markers to assess correlation ...  Read More

Original Research Molecular Pathology
4. Investigation of HER-2 expression and its Correlation with clinicopathological parameters and overall survival of esophageal squamous cell carcinoma patients

Mitra Heidarpour; Mehran Taheri; Ali Akhavan; Parvin Goli; Amirhosein Kefayat

Volume 15, Issue 4 , Autumn 2020, Pages 274-281

http://dx.doi.org/10.30699/ijp.2020.113829.2235

Abstract
  Background & Objective: Human epidermal growth factor receptor 2 (HER-2) exhibits a vast range of expression in esophageal squamous cell carcinoma (ESCC) patients as a biomarker. This paper aimed to investigate HER-2 expression and clinicopathological parameters of esophageal SCC. Methods: HER-2 ...  Read More

Original Research Hematopathology
5. Overexpression of MicroRNA-506 in Jurkat (acute T Cell Leukemia) Cell Line

Shaghayegh Rostami Yasuj; Narges Obeidi; Gholamreza Khamisipour; Zeynab Gharehdaghi; Zivar Zangeneh

Volume 15, Issue 4 , Autumn 2020, Pages 282-291

http://dx.doi.org/10.30699/ijp.2020.119627.2298

Abstract
  Background & Objective:  Acute lymphoblastic leukemia (ALL) is a malignant disease that arises from various mutations in B or T-lymphoid progenitors. MicroRNAs (miRNAs) regulate gene expression by binding to the 3' untranslated region of protein-coding genes. Dysregulation of miRNA expression ...  Read More

Original Research Gynecologic Pathology
6. Association of Human Papilloma Virus and Epstein-Barr Virus with Ovarian Cancer in Shiraz, Southwestern Iran

Mohammad Reza Shokouh; Akbar Safaie; Afagh Moattari; Jamal Sarvari

Volume 15, Issue 4 , Autumn 2020, Pages 292-298

http://dx.doi.org/10.30699/ijp.2020.119681.2306

Abstract
  Background & Objective:  Ovarian cancer is one of the most common cancers amongst women. The association of Human papillomavirus (HPV) and Epstein-Barr virus (EBV) with ovarian cancer is inconclusive; therefore, the aims of this study were to evaluate the frequency of HPV and EBV in malignant, ...  Read More

Original Research Dermatopathology
7. Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

Maral Mokhtari; Farzaneh Mostanbet; Saideh Nekooee Fard; Golsa Shekarkhar; Mozhdeh Sepaskhah; Maryam Sadat Sadati

Volume 15, Issue 4 , Autumn 2020, Pages 299-305

http://dx.doi.org/10.30699/ijp.2020.121365.2320

Abstract
  Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme “Thiopurine S-methyl transferase” (TPMT). Various variants of this enzyme may have decreased ...  Read More

Original Research Hematopathology
8. The Association of FLT3-ITD Gene Mutation with Bone Marrow Blast Cell Count, CD34, Cyclin D1, Bcl-xL and hENT1 Expression in Acute Myeloid Leukemia Patients

Paulus Budiono Notopuro; Jusak Nugraha; Budi Utomo; Harianto Notopuro

Volume 15, Issue 4 , Autumn 2020, Pages 306-312

http://dx.doi.org/10.30699/ijp.2020.122579.2328

Abstract
  Background & Objective:  FLT3-ITD has been recently used as a molecular prognostic marker for risk classification in acute myeloid leukemia (AML) therapy. In this study we aimed to investigate the association of FLT3-ITD gene mutation with bone marrow blast cell count, CD34 expression as ...  Read More

Original Research Molecular Pathology
9. Comparison of patient-collected and lab technician-collected nasopharyngeal and oropharyngeal swabs for detection of COVID-19 by RT-PCR

Alireza Abdollahi; Abbas Shakoori; Hoda Khoshnevis; Mohammad Arabzadeh; Seyed Ali Dehghan Manshadi; Esmaeil Mohammadnejad; Dorsa Ghasemi; Maryam Safari Aboksari; Shaban Alizadeh; Vahid Mehrtash; Arezoo Eftekhar-javadi; Masoomeh Safaei

Volume 15, Issue 4 , Autumn 2020, Pages 313-319

http://dx.doi.org/10.30699/ijp.2020.127312.2387

Abstract
  Background & Objective:  A simple approach to prevent close contact in healthcare settings during the COVID-19 outbreak is to train patients to collect their own nasopharyngeal and oropharyngeal swabs and deliver them to medical laboratories to have them processed. The aim of our study ...  Read More

Original Research Molecular Pathology
10. Genetic Diversity of ctxB Gene Among Classical O1 and El Tor Strains of Vibrio cholerae using High-Resolution Melting Curve Analysis

Mahdieh Mahboobi; Reza Mirnejad; Hamid Sedighian; Vahhab Piranfar; Abbas Ali Imani Fooladi

Volume 15, Issue 4 , Autumn 2020, Pages 320-325

http://dx.doi.org/10.30699/ijp.2020.127793.2393

Abstract
  Background & Objective:  Vibrio cholerae is a natural inhabitant of the environment and causes severe diarrhea ailments (cholera) that affects thousands of people each year worldwide. The most important virulence factors of this pathogen are cholera toxin (cholera toxin CT) and Type IV ...  Read More

Original Research Hematopathology
11. Matrix metalloproteinase-9 (MMP-9) Expression in Non-Small Cell Lung Carcinoma and Its Association with Clinicopathologic Factors

Amir Hossein Jafarian; Melika Kooshki forooshani; Hossein Reisi; Nema Mohamadian roshan

Volume 15, Issue 4 , Autumn 2020, Pages 326-333

http://dx.doi.org/10.30699/ijp.2020.95177.1940

Abstract
  Background & Objective:  Matrix metalloproteinases-9 (MMP-9) is one of the most important enzymes to breakdown extracellular matrix which plays a major role in tumor invasion and metastasis. This study aimed to determine tumor MMP-9 expression in non-small-cell lung carcinoma (NSCLC) and ...  Read More

Case Reports Gynecologic Pathology
12. Coexistence of Benign Brenner Tumor with Mucinous Cystadenoma in an Ovarian Mass

Farzaneh Nazari; Zahra Dehghani

Volume 15, Issue 4 , Autumn 2020, Pages 334-337

http://dx.doi.org/10.30699/ijp.2020.104017.2052

Abstract
  Ovarian cancer is the most lethal gynecologic malignancy. The surface epithelial tumor is the most common type of ovarian cancer. Among these, the mucinous tumors account for 10-15% of ovarian tumors. Mucinous ovarian tumors are among the most difficult ovarian neoplasms for surgical pathologists to ...  Read More

Case Reports GI, Liver & Pancreas Pathology
13. Orthotopic Liver Transplantation for Etanercept-Induced Acute Hepatic Failure; a case report

Dorsay Sadeghian; Farid Azmoudeh-Ardalan; Simin Dashti-Khavidaki; Nasir Fakhar

Volume 15, Issue 4 , Autumn 2020, Pages 338-341

http://dx.doi.org/10.30699/ijp.2020.117000.2269

Abstract
  The occurrence of hepatotoxicity following etanercept (tumor necrosis factor-alpha antagonist) prescription, has been studied well. However, an acute hepatic failure leading to liver transplant as an adverse effect of this drug has not been reported in the literature. In this article, we are going to ...  Read More

Case Reports Nephropathology
14. A Rare Case of Metastasis of Renal Clear Cell Carcinoma to the Thyroid Gland, Presenting as a Goiter Nodule, Three Years After Nephrectomy

Hedieh Moradi Tabriz; Arezoo Eftekhar-Javadi; Atiieh Zandnejadi

Volume 15, Issue 4 , Autumn 2020, Pages 342-345

http://dx.doi.org/10.30699/ijp.2020.117839.2282

Abstract
  Thyroid gland metastatic tumors are rare in clinical practice. Clear cell RCC is one of common metastatic tumors to thyroid. We here reported a case of incidentally found clear cell renal carcinoma metastasis to the thyroid gland 3 years after nephrectomy, in the thyroidectomy procedure performed for ...  Read More

Case Reports Diagnostic Pathology
15. Intravascular Large B-cell Lymphoma: A Report of Two Cases

Fereshteh Ameli; Fatemeh Nili; Hana Saffar

Volume 15, Issue 4 , Autumn 2020, Pages 346-350

http://dx.doi.org/10.30699/ijp.2020.119590.2299

Abstract
  One of the rare variants of extranodal large B-cell lymphoma is intravascular large B-cell lymphoma (IVLBCL). Characteristics of IVLBCL include intraluminal selective proliferation of atypical lymphoid cells in small to medium-sized vessels. The etiologic of IVLBCL is unknown, but due to the growth pattern ...  Read More

Letters to the Editor Cytology
16. Is Micronucleus Assay Suitable for Cytogenetic Biomonitoring the Different Ways to Smoke?

Daniel Ribeiro; Ingra Malacarne; Daniel Souza

Volume 15, Issue 4 , Autumn 2020, Pages 351-351

http://dx.doi.org/10.30699/ijp.2020.125206.2370

Abstract
  The aim of the letter to editor is to provide some comments regarding the manuscript of DehghanNezhad et al.(1) recently published in the Iranian Journal of Pathology titled “Micronucleus Assay of Buccal Mucosa Cells in Waterpipe (Hookah) Smokers: A Cytologic Study.” In this article, the ...  Read More

Letters to the Editor Cytology
17. Response to letter to the editor:” Is micronucleus assay suitable for cytogenetic biomonitoring the different ways to smoke? ”

Noushin Jalayer naderi

Volume 15, Issue 4 , Autumn 2020, Pages 352-354

http://dx.doi.org/10.30699/ijp.2020.127517.2390

Abstract
  Dear Editor, I was very pleased to find that the article” Micronucleus Assay of Buccal Mucosa Cells in Waterpipe (Hookah) Smokers: A Cytologic Study “(1) has attracted the attention of some readers and has created a few points for them. In my opinion, these points are good bases to overcome ...  Read More

Transfusion
1. The Novel Coronavirus SARS-CoV-2 Vulnerability Association with ABO/Rh Blood Types

Alireza Abdollahi; Maedeh Mahmoudi-aliabadi; Vahid Mehrtash; Bita Jafarzadeh; Mohammadreza Salehi

Volume 15, Issue 3 , Summer 2020, , Pages 156-160

http://dx.doi.org/10.30699/ijp.2020.125135.2367

Abstract
  Background & Objective: Coronavirus disease 2019 (COVID-19) is the most recent emerging viral disease. Defining the epidemiological aspects and factors influencing the susceptibility of the patients to COVID-19 has been an ongoing struggle. In the present study, we have investigated the connection ...  Read More

Microbiology
2. Serology Testing for SARS-CoV-2: Benefits and Challenges

Mohammadreza Jalali Nadoushan; Soha Ahmadi; Paniz Jalali Nadoushan

Volume 15, Issue 3 , Summer 2020, , Pages 154-155

http://dx.doi.org/10.30699/ijp.2020.39841

Abstract
  As COVID-19 was declared as a pandemic by the World Health Organization (WHO) in March 2020, it is an emerging need to discuss different aspects of this pandemic. In any pandemic, valid and rapid laboratory diagnostic tests are critically important for early diagnosis, which will increase the rate of ...  Read More

Neuropathology
3. Histopathological Spectrum of Meningiomas with Emphasis on Prognostic Role of Ki67 Labelling Index

Girish Solanke; Vidya Monappa; Ranjini Kudva

Volume 15, Issue 3 , Summer 2020, , Pages 197-204

http://dx.doi.org/10.30699/ijp.2020.107195.2119

Abstract
  Background & Objective: Meningiomas are the most frequently encountered primary non-glial tumors of the central nervous system (CNS). The Ki67 labelling index (Ki67LI) is a proliferation marker that may prove useful in determining the histological grade. This study aims at: 1) Studying the frequency, ...  Read More

Diagnostic Pathology
4. Necessity of Routine Repeat Testing of Critical Values in Various Working Shifts

Hiva Saffar; Alireza Abdollahi; Atefe Sadat Hosseini; Mojgan Torabi Farsani; Ghazal Hajinasrollah; Pegah Mohaghegh

Volume 15, Issue 3 , Summer 2020, , Pages 161-166

http://dx.doi.org/10.30699/ijp.2020.99403.1980

Abstract
  Background & Objective: Accurate and timely reporting of critical values is an important issue. There is some doubt whether repeat testing of critical values would offer any advantage over single testing or not. The aim of this study was evaluation of utility of routine repeat testing of critical ...  Read More

Oral Pathology
5. Detection of Apoptosis in Leukoplakia and Oral Squamous Cell Carcinoma using Methyl Green Pyronin and Hematoxylin and Eosin

Pooja Sharma; Anjali Narwal; Mala Kamboj

Volume 15, Issue 3 , Summer 2020, , Pages 189-196

http://dx.doi.org/10.30699/ijp.2020.107263.2115

Abstract
  Background & Objective: Cell population and turnover are controlled by a balance between cell proliferation and apoptosis. Detection of apoptosis in oral cancer contributes to its better prognosis and improved management. This study aimed to quantify apoptotic cells in leukoplakia and oral squamous ...  Read More

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