Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Number of Volumes 16
Number of Issues 62
Number of Articles 783
Number of Contributors 2,449
View Per Article 1451.02
PDF Download Per Article 868.8
Number of Submissions 1,529
Number of Indexing Databases 48
Number of Reviewers 546

Iranian Journal of Pathology (Iran J Pathol)

Quarterly Journal of Anatomical and Clinical Pathology

The IRANIAN JOURNAL OF PATHOLOGY (IJP),  is an international journal and publishes original research papers, reviews, case  reports, short communications and letters to editor with priority for  high quality original papers on mechanisms of disease and clinical trials. We accept manuscripts that report important findings  on disease pathogenesis and basic biological mechanisms that relate to disease without preferences for a  specific method of analysis. High priority is given to  studies on human diseases and relevant experimental models that use cellular, molecular, biochemical & immunological approaches in conjunction with morphology, and to manuscripts that report new diagnostic methods or analytical systems and their application in studies of disease pathogenesis and diagnosis.   

 

  • Bone and Soft Tissue Pathology,
  • Dermatopathology,
  • Biochemistry,
  • Biology & Genetic,
  • Infectious Diseases,
  • Microbiology,
  • GI pathology & Hepatopathology,
  • Endocrine Pathology,
  • ENT & Ophthalmic Pathology,
  • Gynecologic & Breast Pathology,
  • Molecular Pathology,
  • Nephropathology,
  • Neuropathology,
  • Neuroscience and Anatomy,
  • Oncology & Hematology,
  • Oral Pathology,
  • Pediatric Pathology,
  • Surgical Pathology,
  • Diagnostic Pathology,
  • Uropathology

 

             

 

Review Article Molecular Pathology
1. Pre-analytical Practices in the Molecular Diagnostic Tests, A Concise Review

Maryam Sotoudeh Anvari; Atoosa Gharib; Maryam Abolhasani; Aileen Azari-Yaam; Farzaneh Hossieni Gharalari; Moeinadin Safavi; Ali Zare-Mirzaie; Mohammad Vasei

Volume 16, Issue 1 , Winter 2021, Pages 1-19

http://dx.doi.org/10.30699/ijp.2020.124315.2357

Abstract
  Molecular assays for detection of nucleic acids in biologic specimens are valuable diagnostic tools supporting clinical diagnoses and therapeutic decisions. Pre-analytical errors, which occur before or during processing of nucleic acid extraction, contribute a significant role in common errors which ...  Read More

Original Research Head and Neck Pathology
2. The Frequency of Human Papillomavirus Positivity in Iranian Patients with Head and Neck Squamous Cell Carcinoma

Mitra Rezaei; Mahboobeh Karimi-Galougahi; Azin Kheradmand; Mihan Pourabdollah Toutkaboni; Hassan Mir Mohammad Sadeghi; Alireza Abdollahi; Amirnader Emami Razavi; Ali Safavi Naini; Farahnaz Bidari- Zerehpoosh

Volume 16, Issue 1 , Winter 2021, Pages 20-26

http://dx.doi.org/10.30699/ijp.2020.119344.2300

Abstract
  Background & Objective: Human papillomavirus (HPV) has been associated with prognosis in patients with head and neck squamous cell carcinoma (HNSCC). Similar to the global studies, different prevalence rates of this viral infection have been reported in Iran. Therefore, we aimed to report the prevalence ...  Read More

Original Research Breast Pathology
3. Evaluation of the Relationship Between Expression of Villin and Gelsolin Genes and Axillary Lymph Node Metastasis in Patients with Breast Cancer

Armin Borhan; Zohreh Nozarian; Alireza Abdollahi; Reza Shahsiah; Hadiseh Mohammadpour; Arash Borhan

Volume 16, Issue 1 , Winter 2021, Pages 27-32

http://dx.doi.org/10.30699/ijp.2020.121532.2322

Abstract
  Background & Objective: Nowadays, actin-binding proteins such as Villin and Gelsolin have been considered to be associated with aggressive tumors. This study mainly aims to determine the relationship between Gelsolin and Villin genes expression and metastasis of axillary lymph nodes in patients with ...  Read More

Original Research Diagnostic Pathology
4. Comparison of Immunohistochemistry Expression of CK7, HMWK and PSA in High-Grade Prostatic Adenocarcinoma and Bladder Transitional Cell Carcinoma

Reza Gheitasi; Esmaeil Sadeghi; Mohammad Jafari

Volume 16, Issue 1 , Winter 2021, Pages 33-39

http://dx.doi.org/10.30699/ijp.2020.123998.2353

Abstract
  Background & Objective: Prostate adenocarcinoma is the most common malignancy in males, and the urothelial bladder carcinoma is also prevalent. The histological characteristic of these two tumors is very similar in high-grade cases, and their differentiation is difficult. This study was performed ...  Read More

Original Research GI, Liver & Pancreas Pathology
5. Clinicopathological Significance of Tumor Stem Cell Markers ALDH1 and CD133 in Colorectal Carcinoma

maryam Rezaee; Elmira Gheytanchi; Zahra Madjd; Mitra Mehrazma

Volume 16, Issue 1 , Winter 2021, Pages 40-50

http://dx.doi.org/10.30699/ijp.2020.127441.2389

Abstract
  Background & Objective: Colorectal cancer (CRC) is the third most common cancer worldwide with a high mortality rate. The main causes of death in patients are recurrence and metastasis which are mainly attributed to the small subpopulation of cells within tumors called cancer stem cells (CSCs). This ...  Read More

Original Research Dermatopathology
6. Prevalence and Main Determinants of BRAF V600E Mutation in Dysplastic and Congenital Nevi

Maryam Nasimi; alireza Ghanadan; Kambiz Kamyab; vahidesadat Azhari; Tahereh Yousefi

Volume 16, Issue 1 , Winter 2021, Pages 51-56

http://dx.doi.org/10.30699/ijp.2020.130968.2451

Abstract
  Background & Objective: Predicting the transformation of dysplastic or congenital nevi into malignant lesions results in a significant increase in the survival of patients. Some specific gene mutations have been reported to be very helpful in this regard. Therefore, this study aimed to evaluate the ...  Read More

Original Research Biology & Genetic
7. Cytogenetic Study of Patients with Primary Amenorrhea in the Northeast of Iran

Narjes Soltani; Farzaneh Mirzaei; Hossein Ayatollahi

Volume 16, Issue 1 , Winter 2021, Pages 57-61

http://dx.doi.org/10.30699/ijp.2020.115747.2258

Abstract
  Background & Objective: Primary amenorrhea refers to the absence of menstruation in females of reproductive by age 16 when the development of secondary sexual characteristics is evident (breast development, pubic hair) or by age 14 when there are no secondary sexual characteristics are present. Primary ...  Read More

Original Research Molecular Pathology
8. Variants of Genes Involved in Metabolism of Folate among Patients with Breast Cancer: Association of TYMS 3R Allele with Susceptibility to Breast Cancer and Metastasis

Zohreh Rahimi; Maryam Bozorgi Zarini Bozorgi Zarini; Ziba Rahimi; Ebrahim Shakiba; Asad Vaisi-Raygani; Mohammad Taher Moradi; Kheirolah Yari

Volume 16, Issue 1 , Winter 2021, Pages 62-68

http://dx.doi.org/10.30699/ijp.2020.117676.2283

Abstract
  Background & Objective: Breast cancer (BC) is known to be the most prevalent cancer among women. One-carbon metabolism (OCM) disturbance might play an important role in the etiology of BC. The present study aimed to investigate the thymidylate synthase (TYMS), 5-methyltetrahydrofolate-homocysteine ...  Read More

Short Communication Uropathology
9. Five-year Survival Rate of Bladder Cancer in Iran during 2001-2007

Maryam Khayamzadeh; Fereshte Aliakbari; Zahra Zolghadr; Majid Emadeddin; Mahsa Ahadi; MohammadEsmaeil Akbari; Amir Reza Abedi; Shahrzad Nematollahi; Seyed Jalil Hosseini

Volume 16, Issue 1 , Winter 2021, Pages 69-74

http://dx.doi.org/10.30699/ijp.2020.118375.2287

Abstract
  Background & Objective: Bladder cancer is the fourth most common cancer in men and the most common cancer in women, comprising 8% of all males and 3% of female tumors. The present study aimed to estimate the five-year survival rates of bladder cancer in Iran. Methods: Information on3,337 registered ...  Read More

Short Communication Diagnostic Pathology
10. Online Assessment for Pathology Residents during the COVID-19 Pandemic: Report of an Experience

Alireza Abdollahi; Ali Labbaf; Mahboobeh Mafinejad; Maryam Sotoodeh-Anvari; Farid Azmoodeh-Ardalan

Volume 16, Issue 1 , Winter 2021, Pages 75-78

http://dx.doi.org/10.30699/ijp.2020.129558.2425

Abstract
  Background & Objective: The world is facing COVID-19 pandemic, and medical education system and consequently the evaluation of students at different levels have been overshadowed. Residency students are among those affected. In the present study, we aim to share our experiences regarding holding ...  Read More

Case Reports Dermatopathology
11. Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report

Fatmagul Kusku; Damlanur Sakiz

Volume 16, Issue 1 , Winter 2021, Pages 79-83

http://dx.doi.org/10.30699/ijp.2020.128904.2408

Abstract
  Coronavirus is a single-stranded RNA virus that causes acute respiratory syndrome and various skin lesions. In addition, ischemic acral lesions have been reported in patients with severe coronavirus disease 2019 (COVID-19) due to coagulation disorders. We here present a case with ischemic acral lesions ...  Read More

Case Reports Neuropathology
12. Gliosarcoma with Adenoid and Chondrosarcomatous Differentiation: A Case Report

Elham Jafari; Shiva Didehban; Shahriar Dabiri; Behshad Mofid

Volume 16, Issue 1 , Winter 2021, Pages 84-89

http://dx.doi.org/10.30699/ijp.2020.122606.2330

Abstract
  A heterogeneous group of CNS tumors are characterized by mixed neuroepithelial and mesenchymal features. Glial tumors manifesting this phenomenon are referred to as gliosarcoma. These tumors are usually mistaken for cerebral metastases or meningioma at operation. Their histological studies have revealed ...  Read More

Case Reports Neuropathology
13. Postoperative Extra-Cranial Metastasis of Glioblastoma: A Case Report

atieh zandnejadi; Arezoo Eftekhar-Javadi; HEDIEH MORADI TABRIZ

Volume 16, Issue 1 , Winter 2021, Pages 90-94

http://dx.doi.org/10.30699/ijp.2020.122780.2349

Abstract
  Glioblastoma (WHO grade IV) is the most common malignant tumor of neural tissues in adults as a primary tumor. Because of blood brain barrier and short median survival of patients with glioblastoma, metastasis of this tumor is very rare. A 46-year-old man was admitted to Sina hospital with chief complaint ...  Read More

Letters to the Editor Biology & Genetic
14. Peer Review Publication Skills Matter for Academicians

Payam Behzadi

Volume 16, Issue 1 , Winter 2021, Pages 95-96

http://dx.doi.org/10.30699/ijp.2020.129608.2426

Abstract
  Dear Editor On July 21 (Sunday) and 23 (Tuesday) 2019, I had an opportunity to hold another workshop titled “How to write a scientific paper?” for Ph.D. students in Microbiology Department, Basic Sciences Faculty, the Islamic Azad University, Shahr-e-Qods Branch, Tehran, Iran. I received ...  Read More

Transfusion
1. The Novel Coronavirus SARS-CoV-2 Vulnerability Association with ABO/Rh Blood Types

Alireza Abdollahi; Maedeh Mahmoudi-aliabadi; Vahid Mehrtash; Bita Jafarzadeh; Mohammadreza Salehi

Volume 15, Issue 3 , Summer 2020, , Pages 156-160

http://dx.doi.org/10.30699/ijp.2020.125135.2367

Abstract
  Background & Objective: Coronavirus disease 2019 (COVID-19) is the most recent emerging viral disease. Defining the epidemiological aspects and factors influencing the susceptibility of the patients to COVID-19 has been an ongoing struggle. In the present study, we have investigated the connection ...  Read More

Microbiology
2. Serology Testing for SARS-CoV-2: Benefits and Challenges

Mohammadreza Jalali Nadoushan; Soha Ahmadi; Paniz Jalali Nadoushan

Volume 15, Issue 3 , Summer 2020, , Pages 154-155

http://dx.doi.org/10.30699/ijp.2020.39841

Abstract
  As COVID-19 was declared as a pandemic by the World Health Organization (WHO) in March 2020, it is an emerging need to discuss different aspects of this pandemic. In any pandemic, valid and rapid laboratory diagnostic tests are critically important for early diagnosis, which will increase the rate of ...  Read More

Neuropathology
3. Histopathological Spectrum of Meningiomas with Emphasis on Prognostic Role of Ki67 Labelling Index

Girish Solanke; Vidya Monappa; Ranjini Kudva

Volume 15, Issue 3 , Summer 2020, , Pages 197-204

http://dx.doi.org/10.30699/ijp.2020.107195.2119

Abstract
  Background & Objective: Meningiomas are the most frequently encountered primary non-glial tumors of the central nervous system (CNS). The Ki67 labelling index (Ki67LI) is a proliferation marker that may prove useful in determining the histological grade. This study aims at: 1) Studying the frequency, ...  Read More

Diagnostic Pathology
4. Necessity of Routine Repeat Testing of Critical Values in Various Working Shifts

Hiva Saffar; Alireza Abdollahi; Atefe Sadat Hosseini; Mojgan Torabi Farsani; Ghazal Hajinasrollah; Pegah Mohaghegh

Volume 15, Issue 3 , Summer 2020, , Pages 161-166

http://dx.doi.org/10.30699/ijp.2020.99403.1980

Abstract
  Background & Objective: Accurate and timely reporting of critical values is an important issue. There is some doubt whether repeat testing of critical values would offer any advantage over single testing or not. The aim of this study was evaluation of utility of routine repeat testing of critical ...  Read More

Oral Pathology
5. Detection of Apoptosis in Leukoplakia and Oral Squamous Cell Carcinoma using Methyl Green Pyronin and Hematoxylin and Eosin

Pooja Sharma; Anjali Narwal; Mala Kamboj

Volume 15, Issue 3 , Summer 2020, , Pages 189-196

http://dx.doi.org/10.30699/ijp.2020.107263.2115

Abstract
  Background & Objective: Cell population and turnover are controlled by a balance between cell proliferation and apoptosis. Detection of apoptosis in oral cancer contributes to its better prognosis and improved management. This study aimed to quantify apoptotic cells in leukoplakia and oral squamous ...  Read More

Original Research Biochemistry
1. Hypocalcemia in Covid-19: A Prognostic Marker for Severe Disease

Ahmad Raesi; Ebrahim Saedi Dezaki; Hamideh Moosapour; Farzaneh Saeidifard; Zahra Habibi; Fereidoun Rahmani; Soleiman Kheiri; Elham Taheri

Articles in Press, Accepted Manuscript, Available Online from 24 October 2020

http://dx.doi.org/10.30699/ijp.2020.130491.2442

Abstract
  Introduction: Previous studies have addressed the electrolyte abnormalitiessuch as hypocalcemiain COVID-19 patients. We aimed to compare the laboratory findings especially the electrolyte levels amongCOVID-19 patients and healthy controls and evaluate their prognostic values. Materials and Methods: This ...  Read More

Original Research
2. Protective Effect of Combined Long Time Administration of Selenium and Vitamin C on Liver and Kidney Toxicity of Cadmium in Rats

Mohammad Mahdi Zamani; Vahhab Piranfar; Seyedeh Hamideh Mortazavi; Maryam Monajemzade; Zahra Aalidaeijavadi; Azam Bakhtiarian

Articles in Press, Accepted Manuscript, Available Online from 23 November 2020

http://dx.doi.org/10.30699/ijp.2020.135777.2489

Abstract
  Background and Objective: Increased industrial activities leads to prolonged human exposure to industrial pollutant such as cadmium (Cd). ‍Chronic exposure to Cd in Mammals and also human being, can cause damages to various organs and particularly kidneys and liver. The goal of this study was to ...  Read More

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