Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
GI, Liver & Pancreas Pathology
Immunohistochemical Expression of CDX2 in Gastric Carcinoma

Avan Sardar Ahmed; Jalal Ali Jalal; Kalthuma Salih Hamad Ameen

Volume 17, Issue 2 , April 2022, , Pages 143-149

http://dx.doi.org/10.30699/ijp.2022.530631.2648

Abstract
  Background & Objective: Gastric cancer (GC) persists to be a major health issue globally, and the need to investigate new molecular markers for improving the survival of patients continues. CDX2 is a homeobox caudal protein family member encoded by the CDX2 gene and is probably playing a role in ...  Read More

Gynecologic Pathology
Significance of Endocan Expression in Various Types of Epithelial Ovarian Tumors

Maryam Entezarian; Fereshteh Ameli; Noraidah Masir; Tan Geok Chin

Volume 17, Issue 2 , April 2022, , Pages 202-209

http://dx.doi.org/10.30699/ijp.2022.540192.2740

Abstract
  Background & Objective: Ovarian cancer is associated with the highest mortality rate among gynecologic malignancies. Despite new therapeutic strategies, ovarian cancer still has a high risk of metastasis and mortality. Endocan is a newly identified endothelial cell activation marker, which is responsible ...  Read More

Uropathology
The Expression of Autophagy Markers Beclin1 and LC3B in Prostatic Carcinoma: Immunohistochemical Case-Control Study

Nanis Shawky Holah; Marwa Mohammed Serag El-Dien; Shereen Fathy Mahmoud

Volume 17, Issue 1 , January 2022, , Pages 75-84

http://dx.doi.org/10.30699/ijp.2021.530887.2649

Abstract
  Background and Objective: Prostatic carcinoma represents the second most common cancer diagnosed in men worldwide after lung cancer and the fourth common male malignancy in Egypt. Autophagy is a natural process that has both oncogenic and tumor-suppressive activities. This study aims to evaluate the ...  Read More

Breast Pathology
Role of Cell Block Technology as an Adjunct to Fine Needle Aspiration in Evaluating as well as Differentiating Liver Lesions

Sujata Mallick; Mahasweta Mallik; Rabindra Nath Chatterjee; Puskar Shyam Chowdhury

Volume 16, Issue 4 , August 2021, , Pages 392-402

http://dx.doi.org/10.30699/ijp.2021.522897.2569

Abstract
  Background & Objective: Liver lesions are difficult to diagnose and to differentiate primary from metastatic carcinoma, while Biopsy has its limitations. Cell block technology is easily accessible with high diagnostic accuracy. Our aim is 1) To find the role of cell block technology as an alternative ...  Read More

GI, Liver & Pancreas Pathology
Annexin Expression in Cholangiocarcinoma, and Metastatic Pancreatic Ductal Adenocarcinoma “Is it be Helpful for Differential Diagnosis of These Tumors in the Liver?”

Bita Geramizadeh; Mahsa Sehat; Azam Mehrmozayan; Alireza Shojazadeh

Volume 16, Issue 4 , August 2021, , Pages 433-438

http://dx.doi.org/10.30699/ijp.2021.138493.2512

Abstract
  Background & Objective: Differential diagnosis between cholangiocarcinoma (CCA) and metastatic pancreatic ductal adenocarcinoma (PDA) in the liver is difficult and so far, no specific immunohistochemical marker is reported to differentiate these two tumors. Considering the existing literature, the ...  Read More

Cardiovascular Pathology
Primary Pericardial Epithelioid Angiosarcoma: A Diagnostic Dilemma: A Case Report

Tahmineh Mollasharifi; Behrang Kazeminezhad

Volume 16, Issue 4 , August 2021, , Pages 448-450

http://dx.doi.org/10.30699/ijp.2021.136440.2494

Abstract
  The incidence of pericardial epithelioid angiosarcoma is rare. Angiosarcoma of pericardium may coat the pericardium in a diffuse fashion. Diagnosis of an angiosarcoma is challenging and may be easily mistaken as constrictive pericarditis. Herein, a case of primary pericardial angiosarcoma is reported ...  Read More

Breast Pathology
Myofibroblastoma of the Breast: A Morphologic and Immunohistochemical Study of Three Cases

Hiva Saffar; Dorna Motevalli; Nasibeh Seirfar; Mahsa Ebrahimi; Perikala Vijayananda Kumar; Farid Kosari; Hedieh Moradi Tabriz; Sadaf Naderi; Golsa Shekarkhar

Volume 16, Issue 4 , August 2021, , Pages 451-455

http://dx.doi.org/10.30699/ijp.2021.138647.2520

Abstract
  Myofibroblastoma (MFB) of the breast is an uncommon entity of benign spindle neoplasms of the breast. This tumour possesses a broad spectrum of histomorphological patterns. Distinguishing of myofibroblastoma variants from malignant mimics of this benign neoplasm is essential for pathologists to avoid ...  Read More

Uropathology
Expression of PAX2 and PAX8 in Wilms Tumor: A Tissue Microarray-based Immunohistochemical Study

Salma Sefidbakht; Atieh Khorsand-Rahimzadeh; Sahar Omidi; Sedigheh Mohsenpourian; Elham Mirzaian

Volume 16, Issue 3 , July 2021, , Pages 310-315

http://dx.doi.org/10.30699/ijp.2021.139752.2527

Abstract
  Background & Objective: There is currently inadequate information about the expression of immunohistochemical markers in pediatric tumors. Paired box genes 2 and 8 (PAX2 and PAX8) genes have an essential role in kidney organogenesis. This study aimed to investigate the IHC expression of PAX2 and ...  Read More

GI, Liver & Pancreas Pathology
Microsatellite Instability and Colorectal Cancer, Immunohistochemical and Molecular Evaluation by Using DNA Sequencing: A Single Center Experience

Bita Geramizadeh; Farzaneh Bozorg-Ghalati; Firoozeh Jafari; Mitra Mirzai; Zahra Jowkar

Volume 16, Issue 3 , July 2021, , Pages 325-331

http://dx.doi.org/10.30699/ijp.2021.135222.2481

Abstract
  Background & Objective: Microsatellite instability is common in familial colorectal cancers. It can be tested by the molecular and immunohistochemical methods. There are very few studies which address comparing the clinicopathological characteristics of microsatellite stable (MSS) and microsatellite ...  Read More

Neuropathology
Expression and Prognostic Significance of Cancer/Testis Antigens, MAGE-E1, GAGE, and SOX-6, in Glioblastoma: An Immunohistochemistry Evaluation

Seyed Abbas Tabatabaei Yazdi; Masoomeh Safaei; Mehran Gholamin; Alireza Abdollahi; Fatemeh Nili; Mehdi Jabbari Nooghabi; Kazem Anvari; Majid Mojarrad

Volume 16, Issue 2 , April 2021, , Pages 128-136

http://dx.doi.org/10.30699/ijp.2020.125038.2368

Abstract
  Background & Objectives: Glioblastoma is the most common primary malignancy of the brain, the prognosis of which is poor. Immunotherapy with cancer/testis (CT) antigens is a novel therapeutic approach for glioblastoma. This study aimed to investigate the expression rate of MAGE-E1, GAGE, and SOX-6 ...  Read More

Pulmonary Pathology
The Diagnostic and Prognostic Roles of Combined Expression of Novel Biomarkers in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC); An Immunohistochemical Study

Mohamed Alabiad; Ola Harb; Mohamed Abozaid; Ahmed Embaby; Doaa Mandour; Rehab Hemeda; Amany Shalaby

Volume 16, Issue 2 , April 2021, , Pages 162-173

http://dx.doi.org/10.30699/ijp.2020.130944.2452

Abstract
  Background and Objective: Diagnosis and discrimination of lung adenocarcinoma (LUAD) from lung squamous cell carcinoma (LUSC) is critical to select the appropriate treatment regimen as recently targeted therapies require accurate subtyping of NSCLCs. There are currently several biomarkers that could ...  Read More

Head and Neck Pathology
Reduced Expression of Galectin-8 May Contribute in Carcinogenic Pathway of Head and Neck Squamous Cell Carcinoma

Maryam Ghasemi; Laleh Vahedi Larijani; Jamshid azdani-Charati; Elham Kamali Hakim

Volume 16, Issue 2 , April 2021, , Pages 195-204

http://dx.doi.org/10.30699/ijp.2021.121140.2318

Abstract
  Background & Objectives: Galectin-8 has relationships with cell growth and metastasis of some cancers. Due to controversy in the clinical significance of this protein in the cancer process, we investigated its roles in the development of head and neck squamous cell carcinoma. Methods: This study ...  Read More

Hematopathology
Matrix metalloproteinase-9 (MMP-9) Expression in Non-Small Cell Lung Carcinoma and Its Association with Clinicopathologic Factors

Amir Hossein Jafarian; Melika Kooshki forooshani; Hossein Reisi; Nema Mohamadian roshan

Volume 15, Issue 4 , October 2020, , Pages 326-333

http://dx.doi.org/10.30699/ijp.2020.95177.1940

Abstract
  Background & Objective:  Matrix metalloproteinases-9 (MMP-9) is one of the most important enzymes to breakdown extracellular matrix which plays a major role in tumor invasion and metastasis. This study aimed to determine tumor MMP-9 expression in non-small-cell lung carcinoma (NSCLC) and ...  Read More

Uropathology
Diagnostic Value of Cytokeratin 34 beta E12 (Ck34βE12) and α-Methylacyl-CoA racemase (AMACR) Immunohistochemical Expression in Prostatic Lesions

Ikram A. Hasan; Hiba Gaidan; Methaq Al-kaabi

Volume 15, Issue 3 , July 2020, , Pages 232-238

http://dx.doi.org/10.30699/ijp.2020.113544.2229

Abstract
  Background & Objective:Some prostatic lesions contain small suspicious foci for prostatic carcinoma in which the morphological features are equivocal. Two immunohistochemical markers namely, cytokeratin 34 beta E12 (Ck34βE12) and α-Methylacyl-CoA racemase (AMACR), were evaluated in these ...  Read More

Breast Pathology
Androgen Receptor Expression and Its Correlation with Clinicopathological Parameters in Iranian Patients with Triple Negative Breast Cancer

Azar Naimi; Maryam Sultan; Elham Amjadi; Parvin Goli; Amirhosein Kefayat

Volume 15, Issue 3 , July 2020, , Pages 239-244

http://dx.doi.org/10.30699/ijp.2020.112819.2224

Abstract
  Background & Objective: Our knowledge about correlation of androgen receptor expression and clinicopathological properties of triple-negative breast cancer (TNBC) patients is inadequate, particularly in the Iranian population. The main aim of the present study was to assess the AR expression in TNBC ...  Read More

Head and Neck Pathology
Cyclin D1 Expression in Patients with Laryngeal Squamous Cell Carcinoma

Vahid Zand; Fariba Binesh; Mojtaba Meybodian; Farzan Safi Dahaj; Arezoo Alamdar yazdi

Volume 15, Issue 3 , July 2020, , Pages 245-250

http://dx.doi.org/10.30699/ijp.2020.116579.2276

Abstract
  Background & Objective: Laryngeal squamous cell carcinoma (LSCC) is considered to be one of the most common cancers of the head and neck, accounting for roughly 90% of all malignant tumors of the larynx. To have a timely diagnosis for a better and practical therapy, molecular markers have to be investigated. ...  Read More

Uropathology
Sarcomatoid Carcinoma of the Penis: An Uncommon Penile Neoplasm

Sucheta Gandhe; Rahul Patil; Raj Nagarkar

Volume 15, Issue 2 , April 2020, , Pages 151-153

http://dx.doi.org/10.30699/ijp.2020.117401.2275

Abstract
  Sarcomatoid squamous cell carcinomas are extremely rare, high grade, aggressive variant of penile cancers. Sarcomatoid carcinoma are biphasic neoplasms with a combination of both sarcomatoid components and carcinomatous elements. These neoplasms are very rare in the urogenital system. We report a 53-year-old ...  Read More

Breast Pathology
Assessment of Ki67 in Breast Cancer: A Comparison Between the Eye-10 Method, Stepwise Counting Strategy, and International System of Ki67 Evaluation

Maryam Kadivar; Fatemeh Aram

Volume 15, Issue 1 , January 2020, , Pages 13-18

http://dx.doi.org/10.30699/ijp.2019.102290.2017

Abstract
  Background & Objective:Ki-67 evaluation is an essential tool to define luminal A and B breast cancers, which is not yet systematized. The International Ki67 in Breast Cancer Working Group suggests the counting of 500 or 1000 cancer cells, which is a time-consuming process. Therefore, novel methods, ...  Read More

Uropathology
Solitary Fibrous Tumor of the Prostate: A Diagnostic Challenge: A Case Report

Nilay Nishith; Monika Gupta; Nidhi Kaushik; Rajeev Sen

Volume 15, Issue 1 , January 2020, , Pages 41-44

http://dx.doi.org/10.30699/ijp.2019.104669.2069

Abstract
  Solitary fibrous tumor (SFT) of prostate is an unusual type of mesenchymal neoplasm that can elicit a benign or malignant phenotype. It represents a diagnostic challenge as it can simulate poorly differentiated adenocarcinoma and various mesenchymal neoplasms of prostate. We report a case of prostate ...  Read More

GI, Liver & Pancreas Pathology
Histopathological Evaluation and Analysis of Immunohistochemical Expression of Bcl-2 Oncoprotein in Colorectal Carcinoma

Shilpa Tukaram Patil; Clement Wilfred Devadass; Prasanna Shetty Badila

Volume 14, Issue 4 , October 2019, , Pages 317-321

http://dx.doi.org/10.30699/ijp.2019.102982.2028

Abstract
  Background & Objective: Colorectal cancer is the third most prevalent malignancy with high mortality rate, necessitating markers that predict survival and guide the treatment. Previous studies have examined the immunohistochemical expression of Bcl-2, an apoptotic marker, in colorectal carcinoma, ...  Read More

Prostate Cancer with Intraluminal Inclusions: the Association of the Immunophenotype with Grade Score

Artem Piddubnyi; Anatolii M Romaniuk; Inna-Margaryta Radomychelski; Yuliia Moskalenko; Roman Moskalenko

Volume 14, Issue 3 , August 2019, , Pages 212-222

http://dx.doi.org/10.30699/ijp.2019.91400.1884

Abstract
  Background & Objective: To study the immunophenotype of prostate cancer (PC) with the presence and absence of intraluminal inclusions (IIn), depending on the grade score. Methods: A total of 30 PC samples with IIn (group E) and 30 PC samples without them (group C) were studied. These groups were ...  Read More

Immunology and Serology
An Immunohistochemical Study of Cyclin D1 Expression in Astrocytic Tumors and its Correlation with Tumor Grade

Parvin Mahzouni; Fatemeh Taheri

Volume 14, Issue 3 , August 2019, , Pages 252-257

http://dx.doi.org/10.30699/ijp.2019.82024.1771

Abstract
  Background & Objective: Glioblastoma-multiforme is the high grade form of astrocytic tumors with a short survival time, which are the most common type of brain tumors. Therefore, finding new therapeutic options is essential. Cyclin D1 is expressed in some human malignancies and can be a potential ...  Read More

Gynecologic Pathology
Comparing the Diagnostic Outcomes of Staining Various Breast Lesions with Either Anti-CK 5/6 or Anti-CK 5

Mihir A Gudi; Yiu Yi Chung; Nohadani Mahrokh

Volume 14, Issue 2 , April 2019, , Pages 113-121

http://dx.doi.org/10.30699/ijp.14.2.113

Abstract
  Background and Objective: Anti-CK5/6 monoclonal antibodies have an established role in breast disease diagnosis. Anti-CK5 monoclonal antibodies have recently become commercially available. There has been growing interest in the staining characteristics of anti-CK5 and its potential diagnostic role in ...  Read More

Bone & Soft tissue Pathology
The Role of Immunohistochemistry Studies in Distinguishing Malignant Mesothelioma from Metastatic Lung Carcinoma in Malignant Pleural Effusion

Monireh Halimi; Samad BeheshtiRouy; Davood Salehi; Seyed Ziaeddin Rasihashemi

Volume 14, Issue 2 , April 2019, , Pages 122-126

http://dx.doi.org/10.30699/ijp.14.2.122

Abstract
  Background and Objective: Early diagnosis of malignant pleural mesothelioma (MPM) is the key point of its treatment. The main problem is the precise diagnosis of mesothelioma and its differentiation from metastatic lung adenocarcinoma. Mesothelioma exhibits complex immunohistochemical characteristics. ...  Read More

Oral Pathology
Histochemical and Immunohistochemical Analysis of Collagen Fibers and Microvascular Density in Various Grades of Oral Submucous Fibrosis

Savita S Thakkannavar; Veena V Naik

Volume 14, Issue 2 , April 2019, , Pages 127-134

http://dx.doi.org/10.30699/ijp.14.2.127

Abstract
  Background and Objective: This study was aimed to evaluate the collagen fibers qualitatively and its correlation with microvascular density in various grades of oral submucous fibrosis (OSMF).   Material and Methods: The present study comprised of total 40 cases of oral submucous fibrosis. Picrosirius ...  Read More