Volume 15 (2020)
Volume 14 (2019)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Original Research
1. The Comparison Between Microwave and Autoclave as Antigen Retrieval Methods for Immunohistochemical Detection of CD15 and CD30 in Hodgkin’s Lymphoma

Farid Kosari; Fatemeh Ghaffari

Volume 13, Issue 4 , Autumn 2018, Pages 390-396

Abstract
  Background and Objective: Hodgkin's lymphoma is a potentially curable hematologic malignancy with difficulty in its diagnosis especially in atypical cases even in expert hands. Today, immunohistochemistry plays a significant role in the diagnosis of it especially applying the anti-CD15 and anti-CD30 ...  Read More

Original Research Hematopathology
2. Prevalence of MPL (W515K/L) Mutations in Patients with Negative-JAK2 (V617F) Myeloproliferative Neoplasm in North-East of Iran

Seyyede Fatemeh Shams; Hossein Ayatollahi; Mohammad hadi Sadeghian; Monavar Afzal Aghaee; Sepideh Shakeri; Ehsan Yazdandoust; Maryam Sheikhi; Nafiseh Amini; Samane Bakhshi; Afsane Bahrami

Volume 13, Issue 4 , Autumn 2018, Pages 397-402

Abstract
  Background and Objective: Janus kinase 2 (JAK2) and Myeloproliferative Leukemia (MPL) mutations are confirmatory indicators for Myeloproliferative Neoplasm (MPN). The current study was performed to determine the frequency of MPL mutation in MPN patients without JAK2 mutation, in order to assign MPL mutation ...  Read More

Original Research Microbiology
3. Designing and Construction of a Cloning Vector Encoding mtb32C and mpt51 Fragments of Mycobacterium Tuberculosis as a DNA Vaccine Candidate

Faria Hasanzadeh Haghighi; Ehsan Aryan; Mohammad Derakhshan; Aida Gholoobi; Zahra Meshkat

Volume 13, Issue 4 , Autumn 2018, Pages 403-407

Abstract
  Background & objective:  Tuberculosis (TB) remains a major cause of death around the world. Bacillus Calmette Guérin (BCG) is the only vaccine used in TB prevention that has a protective effect in children, but its effectiveness declines in adults. Design and development of new vaccines ...  Read More

Original Research Biology & Genetic
4. The Effect of Cadmium on Apoptotic Genes mRNA Expression of Bax and Bcl-2 in Small Intestine of Rats

Narjes Seid Alian; Parvin khodarahmi; Vahid Naseh

Volume 13, Issue 4 , Autumn 2018, Pages 408-414

Abstract
  Background: Cadmium is a potent toxicant and carcinogenic in human and experimental animals. The evidence indicates that cadmium induces aberrant gene expression, inhibition of DNA damage repair, and apoptosis. In this study, we investigated the effects of IP (intraperitoneal) injection of cadmium on ...  Read More

Original Research Diagnostic Pathology
5. Molecular Status of BRAF Mutation in Prostate Adenocarcinoma: The Analysis of 100 Cases in North-East of IRAN

Amir Hossein Jafarian; Khatoone Mirshekar; Sare Etemad; Masoumeh Jafaripour; Mansoore Darijani; Maryam Sheikhi; Hossein Ayatollahi; Sepideh Shakeri; Seyyede Fatemeh Shams; Saeed Davari

Volume 13, Issue 4 , Autumn 2018, Pages 415-421

Abstract
  Background and Objective: BRAF mutations were studied in various populations for prostate carcinoma (PC); however, mutations in BRAF gene are unusual compared to KRAS. Oncogenic activating of BRAF mutations were studied lately in almost 0%-10% of prostate cancer cases. Methods: In this retrospective ...  Read More

Original Research Molecular Pathology
6. MiR-21 Expression in Wilms’ Tumor

Navid Bazzaz; Nazila Nouraee Nouraee; Ali Zare-Mirzaie; Seyed Javad Mowla Mowla; Maryam Shahali; Mohammad Vasei

Volume 13, Issue 4 , Autumn 2018, Pages 422-428

Abstract
  Background and Objective: Wilms’ tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been identified. We aimed to evaluate the expression of miR-21, a well-known oncomir, ...  Read More

Original Research
7. Investigation of the rpoB Mutations Causing Rifampin Resistance by Rapid Screening in Mycobacterium Tuberculosis in North-East of Iran

Amir Tajbakhsh; Faezeh Ghasemi; Seyedeh Zohre Mirbagheri; Mastoureh Momen Heravi; Mehdi Rezaee; Zahra Meshkat

Volume 13, Issue 4 , Autumn 2018, Pages 429-437

Abstract
  Background and Objectives: The incidence of rifampin-resistant strains of Mycobacterium tuberculosis has attracted more attention than the tuberculosis infection due to laborious treatment and control. Recognizing the Mycobacterium tuberculosis genotypes involving in drug resistance via multiplex PCR, ...  Read More

Original Research Molecular Pathology
8. Evaluation of the CD123 Expression and FLT3 Gene Mutations in Patients with Acute Myeloid Leukemia

Freidoon Solhjoo; Akbar Safaie; Ahmad Monabati; Maral Mokhtari; Moeinadin Safavi

Volume 13, Issue 4 , Autumn 2018, Pages 438-446

Abstract
  Background and Objective: Identification of cytogenetic and molecular changes plays an important role in acute myeloid leukemia (AML) patients. Thus, they are used in classification, prognosis and treatment of the disease. The CD123 expression and FLT3 gene mutations are also the variations that may ...  Read More

Original Research Biology & Genetic
9. Relationship Between PIK3CA Amplification and P110α and CD34 Tissue Expression as Angiogenesis Markers in Iranian Women with Sporadic Breast Cancer

Shadi Hosseini; Farkhondeh Behjati; Maryam Rahimi; Nazanin Taheri; Hamid Reza Khorram Khorshid; Fatemehte Aghakhani Moghaddam; Saghar Ghasemi Frouzabadi; Masoud Karimlou; Fereidoon Sirati; Elahe Keyhani

Volume 13, Issue 4 , Autumn 2018, Pages 447-453

Abstract
  Background and Objective: The PI3K/AKT/mTOR pathway is known to play an important role in regulating angiogenesis both in normal and breast cancer (BC) tissues. PIK3CA amplification was reported in various malignancies, including approximately 10% of BC cases. The aim of this study was to identify the ...  Read More

Short Communication
10. Application and Assessment of Allogeneic Fibroblasts for Cell Therapy

Seyedeh Mehrnaz Kouhbanani nejad; Farzaneh Armin; Shahriar dabiri; Ali Derakhshani; Maryam Iranpour; Alireza Farsinejad

Volume 13, Issue 4 , Autumn 2018, Pages 454-460

Abstract
  Background and Objective: In recent years, due to increasing number of patients with non-healing skin ulcers, skin substitutes have been used. Skin substitutes contain living cells causing faster and more effective wound healing. Therefore, research on the use of autologous and allogeneic cells such ...  Read More

Short Communication Hematopathology
11. Peripheral Blood-Derived Mesenchymal Stem Cells: Growth Factor-Free Isolation, Molecular Characterization and Differentiation

Noushin Pouryazdanpanah; Shahriar Dabiri; Ali Derakhshani; Reza Vahidi; Alireza Farsinejad

Volume 13, Issue 4 , Autumn 2018, Pages 461-466

Abstract
  Background and Objectives: The mesenchymal stem cells derived from peripheral blood (PB) have been recognized as a promising source for allogeneic cell therapy. The aim of this study was to investigate the isolation, growth and differentiation ability of peripheral blood-isolated mesenchymal stem cells. ...  Read More

Case Reports Gynecologic Pathology
12. Peripheral Primitive Neuroectodermal Tumor of the Ovary: The Report of Two Rare Cases

Fatemeh Nili; Azadeh Sedighi moghadam pour; Hedieh Moradi Tabriz; Parisa Sedighi Moghadam Pour; Hana Saffar

Volume 13, Issue 4 , Autumn 2018, Pages 467-470

Abstract
  Peripheral primitive neuroectodermal tumor (pPNET) is a highly aggressive small round cell tumor belonging to PNET/Ewing sarcoma family. Ovarian tumors composed of primitive neuroectodermal elements are extremely rare. Herein we reported two cases of peripheral primitive neuroectodermal tumors of ovary ...  Read More

Case Reports
13. Osteocartilaginous Choriostoma of Palatine Tonsil: a Rare Hidden Entity

Shilpa Bairwa; Bhawna Sethi; Pawan Singh; Ashok Sangwaiya; Shivani Kalhan

Volume 13, Issue 4 , Autumn 2018, Pages 471-473

Abstract
  A choriostoma is an aggregate of microscopically normal cells or tissues which occurs in an aberrant location. It follows a benign course, rarely seen in head and neck region. A choriostoma of the palatine tonsil is very rare; less than 10 cases were reported till date. A 11-year-old male referred to ...  Read More

Case Reports
14. Metachronous Malignant Fibrous Histiocytoma- A Rare Case Report

Gireesha Rawal; Sufian Zaheer; Amit Yadav; Indrani Dhawan

Volume 13, Issue 4 , Autumn 2018, Pages 474-478

Abstract
  Malignant fibrous histiocytoma (MFH) is one of the most common types of soft tissue sarcomas in adults. Distant metastases are developed in 30–40% of patients with MFH, with the most common site being the lung. However, metachronous MFH has not been reported previously in literature. This report ...  Read More

Letters to the Editor Diagnostic Pathology
15. Aberration of Erythrocyte Sedimentation Rate by Zinc Nanoparticles

sora yaari; Viroj Wiwanitkit

Volume 13, Issue 4 , Autumn 2018, Pages 479-479

Abstract
  Dear Editor, erythrocyte sedimentation rate (ESR) is a useful basic clinical pathology laboratory investigation. It can be helpful in diagnosis and follow-up of several diseases. At present, a new automated method with proven reliability is available for ESR test  (1). Here, the authors report on ...  Read More