Peripheral Primitive Neuroectodermal Tumor of the Ovary: The Report of Two Rare Cases

Document Type: Case Reports

Authors

1 APCP, Dept. of Anatomical and Surgical Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

2 APCP, Dept. of Anatomical and Surgical Pathology and Laboratory Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

3 Radiologist, Guilan University of Medical Sciences, Guilan, Iran

Abstract

Peripheral primitive neuroectodermal tumor (pPNET) is a highly aggressive small round cell tumor belonging to PNET/Ewing sarcoma family. Ovarian tumors composed of primitive neuroectodermal elements are extremely rare.
Herein we reported two cases of peripheral primitive neuroectodermal tumors of ovary in two patients with different clinical presentations. Definite diagnoses were made based on the histomorphology and immunohistochemistry
results.
With respect to different clinical behaviors, treatment modalities and prognosis of peripheral primitive neuroectodermal tumors compared to other known ovarian neoplasms, it is essential to consider this entity as a differential diagnosis in ovarian tumors especially in young patients.

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