Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Biology & Genetic
1. Different Immune Responses in Dangerous O Blood Donors

shaghayegh Arabi; Mostafa Moghadam; Vida Maleki; Ali Akbar Pourfatholah; Afsaneh Aghaie

Volume 15, Issue 1 , Winter 2020, , Pages 34-40

http://dx.doi.org/10.30699/ijp.2019.104673.2075

Abstract
  Background & Objective:Dangerous O is very important to transfusion medicine and there has been reports by Food and Drug Administration (FDA) regarding some death relating incidences. As high iso-antibody production is closely associated with different immune reactions, a survey on the different ...  Read More

Biology & Genetic
2. Cell-bound Exopolysaccharide Extract from Indigenous Probiotic Bacteria Induce Apoptosis in HT–29 cell-line

Parisa Mojibi; Farzaneh Tafvizi; Maryam Bikhof Torbati

Volume 14, Issue 1 , Winter 2019, , Pages 41-51

http://dx.doi.org/10.30699/ijp.14.1.41

Abstract
  Background and Objective: The aim of this study was to compare the cytotoxic effects of local probiotic bacteria, including Lactobacillus paracasei, Lactobacillus brevis, while isolated from “Tarkhine” food and the induction of apoptosis in the HT–29 human colon adenocarcinoma ...  Read More

Biology & Genetic
3. The Effect of Cadmium on Apoptotic Genes mRNA Expression of Bax and Bcl-2 in Small Intestine of Rats

Narjes Seid Alian; Parvin khodarahmi; Vahid Naseh

Volume 13, Issue 4 , Autumn 2018, , Pages 408-414

Abstract
  Background: Cadmium is a potent toxicant and carcinogenic in human and experimental animals. The evidence indicates that cadmium induces aberrant gene expression, inhibition of DNA damage repair, and apoptosis. In this study, we investigated the effects of IP (intraperitoneal) injection of cadmium on ...  Read More

Biology & Genetic
4. Relationship Between PIK3CA Amplification and P110α and CD34 Tissue Expression as Angiogenesis Markers in Iranian Women with Sporadic Breast Cancer

Shadi Hosseini; Farkhondeh Behjati; Maryam Rahimi; Nazanin Taheri; Hamid Reza Khorram Khorshid; Fatemehte Aghakhani Moghaddam; Saghar Ghasemi Frouzabadi; Masoud Karimlou; Fereidoon Sirati; Elahe Keyhani

Volume 13, Issue 4 , Autumn 2018, , Pages 447-453

Abstract
  Background and Objective: The PI3K/AKT/mTOR pathway is known to play an important role in regulating angiogenesis both in normal and breast cancer (BC) tissues. PIK3CA amplification was reported in various malignancies, including approximately 10% of BC cases. The aim of this study was to identify the ...  Read More

Biology & Genetic
5. KRAS Codon 12 and 13 Mutations in Gastric Cancer in the Northeast Iran

Hossein Ayatollahi; Alireza Tavassoli; Amir Hossein Jafarian; Amin Alavi; Sepideh Shakeri; Seyyede Fatemeh Shams; Maryam Sheikhi; Neda Motamedi Rad; Mohammadhadi Sadeghian; Afsane Bahrami

Volume 13, Issue 2 , Spring 2018, , Pages 167-172

http://dx.doi.org/10.30699/ijp.13.2.167

Abstract
  Background & objective: KRAS mutations are reported in many types of cancers including pancreas, lung, colon, breast, and gastric (GC). High frequency of KRAS mutation is observed in the pancreas, colon, and lung cancers; they commonly arise in codon 12 and 13 of exon 2. Due to the lack of information ...  Read More

Biology & Genetic
6. The Association of Gastritis and Peptic Ulcer With Polymorphisms in the Inflammatory-related Genes IL-4 and IL-10 in Iranian Population

Meysam Rezaeishahmirzadi; Neda Motamedi Rad; Mehdi Kalantar; Hossein Ayatollahi; Sepideh shakeri; Maryam Sheikhi; Mohammad Shekari

Volume 13, Issue 2 , Spring 2018, , Pages 229-236

http://dx.doi.org/10.30699/ijp.13.2.229

Abstract
  Background and Objective: The current study aimed at assessing the relationship between gastritis and peptic ulcer susceptibility and inflammation-related gene polymorphisms in Iranian patients. Gastritis and peptic ulcer are common medical complications with serious outcomes on the quality of life. ...  Read More

Biology & Genetic
7. A Review of Driver Genetic Alterations in Thyroid Cancers

Fatemeh Khatami; Mohammad Tavangar

Volume 13, Issue 2 , Spring 2018, , Pages 125-135

http://dx.doi.org/10.30699/ijp.13.2.125

Abstract
  Thyroid cancer is a frequent endocrine related malignancy with continuous increasing incidence. There has been moving development in understanding its molecular pathogenesis recently mainly through the explanation of the original role of several key signaling pathways and related molecular distributors. ...  Read More

Biology & Genetic
8. Classification and Biomarker Genes Selection for Cancer Gene Expression Data Using Random Forest

Malihe Ram; Ali Najafi; Mohammad Taghi Shakeri

Volume 12, Issue 4 , Autumn 2017, , Pages 339-347

http://dx.doi.org/10.30699/ijp.2017.27990

Abstract
  Background & objective: Microarray and next generation sequencing (NGS) data are the important sources to find helpful molecular patterns. Also, the great number of gene expression data increases the challenge of how to identify the biomarkers associated with cancer. The random forest (RF) is used ...  Read More

Biology & Genetic
9. Differentiating and Categorizing of Liposarcoma and Synovial Sarcoma Neoplasms by Fluorescence in Situ Hybridization

Farhad Shahi; Razieh Alishahi; Hossein Pashaiefar; Isa Jahanzad; Naser Kamalian; Ardeshir Ghavamzadeh; Marjan Yaghmaie

Volume 12, Issue 3 , Summer 2017, , Pages 209-217

http://dx.doi.org/10.30699/ijp.2017.25043

Abstract
  Background & Objective: Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumors of mesenchymal origin and various cytogenetic abnormalities ranging from distinct genomic rearrangements, such as chromosomal translocations and amplifications, to more intricate rearrangements ...  Read More

Microbiology
10. Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction (ERIC-PCR) Genotyping of Escherichia coli Strains Isolated from Different Animal Stool Specimens

Reza Ranjbar; Afsar Tabatabaee; Payam Behzadi; Rohollah Kheiri

Volume 12, Issue 1 , Winter 2017, , Pages 25-34

http://dx.doi.org/10.30699/ijp.2017.21506

Abstract
  Background: Escherichia coli is a commensal-pathogenic organism, which includes a wide range of strains. Despite several advanced molecular-genomic technologies for detecting and identifying different strains of E. coli, Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction ...  Read More

Biology & Genetic
11. The Diagnosis of HIV Infection in Infants and Children

Alireza Abdollahi; Hana Saffar

Volume 11, Issue 2 , Spring 2016, , Pages 89-96

Abstract
  It is estimated that the number of HIV infected children globally has increased from 1.6 million in 2001 to 3.3 million in 2012. The number of children below 15 years of age living with HIV has increased worldwide. Published data from recent studies confirmed dramatic survival benefit for infants started ...  Read More

Biology & Genetic
12. Maspin Gene Expression in Invasive Ductal Carcinoma of Breast

Shahriar Dabiri; Mohammadmehdi Moeini aghtaei; Jahanbano Shahryari; Manzume Shamis meymandi; Sahar Amirpour-Rostami; Reza Foutohi-Ardekani

Volume 11, Issue 2 , Spring 2016, , Pages 104-111

Abstract
  Background: The breast cancer is the most prevalent cancer among women, on the other hand absence of myoepithelial cells play a pivotal role in pathogenesis of this cancer. Thus we aimed to investigate the possible abilities of the molecular assay technique to find a relationship between mammary serine ...  Read More