A Simplified Working Classification Proposed for Myxoid Tumors of Oral Cavity

Document Type: Letters to the Editor

Authors

Department of Oral and Maxillofacial Pathology, NIMS Dental College, Jaipur, India

Abstract

Dear Editor-in-Chief
Myxoid tumors of oral cavity encompass a broad spectrum of lesions, primarily neoplastic.(1) The significant variations in the biological behaviour; ranging from completely harmless to malignant neoplasm they require an accurate histopathological diagnosis to ensure a proper treatment. (2) Because of the considerable overlapping between the clinical and histopathological features, this group of tumors often produce a diagnostic difficulty to the clinicians and oral pathologists.(3) An exhaustive review of the literature reveals that there is no approved classification of myxoid tumors of oral cavity. A simple working classification of myxoid tumors is proposed here.

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Main Subjects


Dear Editor-in-Chief

Myxoid tumors of the oral cavity encompass a broad spectrum of lesions, primarily neoplastic (1). Significant variations in the biological behavior ranging from completely harmless to malignant neoplasm require an accurate histopathological diagnosis to ensure a proper treatment (2). A considerable overlapexists between clinical and histopathological features of these group of tumors, which often produces a diagnostic difficulty to clinicians and oral pathologists (3). There is no approved working classification for myxoid tumors of the oral cavity in the literature. A simple working classification of myxoid tumors is proposed here (Table 1)

Table 1. A simple working classification for myxoid tumors of oral cavity

S NO

CATEGORY

TUMORS

1

Adipose tissue tumors

 

Myxolipoma

Myxiliposarcoma

 

2

Neural tumors

 

Myxoid neurofibroma

Neurothakeoma

Malignant peripheral nerve sheath tumor

 

3

Fibroblastic tumors

 

Myxofibroma

Nodular fasciitis

Myxofibrosarcoma

 

4

Chondroblastic tumors

 

Ectomesenchymal chondromyxoid tumor

Myxoid chondrosarcoma

 

5

Muscle tumors

 

Myxoid leiomyosarcoma

 

6

Odontogenic tumors

 

Odontogenic myxoma

7

Miscellaneous

 

Soft tissue myxoma

Ossifying fibromyxoid tumor

Malignant ossifying fibromyxoid tumor

 

This classification is based on the predominance of the areas of myxoid degeneration in histopathology of the tumors of oral cavity. This classification includes adipose, neural, fibroblastic, chondroblastic, muscle, odontogenic and miscellaneous tumors. This classification wouldprovide a better insight into the histopathology of myxoid tumors of oral cavity and wouldbe useful for oral pathologists and cytopathologists.