Document Type : Case Reports


Dept. of Pathology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran


Biliary liver flukes are common parasites in some regions of the world where consumption of raw fresh-water fish is a cultural practice. Clonorchis sinensis and Opisthorchis species are the major biliary liver flukes associated with human disease. Some of these parasites are highly associated with cholangiocarcinoma. This report describes a clinically and epidemiologically unsuspected liver fluke infection associated with cholangiocarcinoma in a middle aged woman from the south shores of Iran, and emphasizes the importance of efforts to discourage raw freshwater fish intake as the route of infection in high risk populations.