Iranian Journal of Pathology

Hodgkin’s Lymphoma Presenting with Myocardial Metastasis and Heart Failure

Document Type : Case Reports

Authors

Maliheh Khoddami1 1
Zeinab Amirimoghaddam 2
Seyed Farzad Azarin 3

1 Associate Professor of Pathology, Shahid Beheshti University of Medical Sciences ,Tehran

2 Assistant professor of Pediatrics, Shahid Beheshti University of Medical Sciences ,Tehran

3 Senior Resident of Pathology, Shahid Beheshti University of Medical Sciences ,Tehran

Abstract
Although involvement of the heart by malignant lymphoma is relatively common, it is unusual to be detected premortem. We report a case of Hodgkin's lymphoma who presented with systemic signs and symptoms including abdominal distension, weakness, pallor, chills and fever, hepatosplenomegaly and generalized lymphadenopathy as well as signs of heart failure. Echocardiography revealed lucent myocardial lesions, pericardial effusion, and left ventricular hypertrophy. Right cervical lymph node and bone marrow biopsies established the diagnosis of nodular sclerosis Hodgkin's lymphoma with bone marrow involvement. After 14 periods of chemotherapy, systemic and cardiac abnormalities improved. To the best of our knowledge, Hodgkin's lymphoma primarily presenting with myocardial metastasis and heart failure is not previously reported.  

Keywords

Hodgkin's lymphoma
Nodular sclerosis
heart failure
Iranian Journal of Pathology
Volume 1, Issue 4 - Serial Number 4
Autumn 2006
Pages 177-180

  • Receive Date 28 September 2014

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