Document Type : Case Reports
Dept. of Oral and Maxillofacial Pathology, Tehran University of Medical Sciences, Tehran, Iran
Leiomyoma is a rare benign neoplasm deriving from smooth muscle. Vascular leiomyoma is its most common subtype in the oral cavity. It may appear at any age with the greatest incidence in the 4th and 5th decade of life. The common manifestation is a slow-growing, asymptomatic, submucousal mass. The diagnosis is only through microscopic examination requiring special staining. Treatment of choice is surgical excision and no recurrence is usually seen. In this report, we present a case of angiomyoma in the midline of hard palate with description of its clinical, histological and immunohistochemical characteristics.
- Al-Amad SH, Angel C, O’Grady JF, McCullough MJ. Angioleiomyoma on the hard palate. Oral Oncol Extra 2006;42:244-6.
- Brooks JK, Nikitakis NG, Goodman NJ, Levy BA. Clinicopathologic characterization of oral angioleiomyomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002 Aug;94(2):221-7.
- Hung KF, Yan AH, Kao SY, Chang CS. Angioleiomyoma in right lingual gingival-a case report. Chin J Oral Maxillofac Surg 2005;16:179-87.
- Gonzalez Sanchez MA, Colorado BM, Berini AL, Gay EC. Leiomyoma of the hard palate: a case report. Med Oral Patol Oral Cir Bucal 2007 May 1;12(3):E221-E224.
- Gaitan Cepeda LA, Quezada RD, Tenorio RF, Leyva Huerta ER, Mendez Sanchez ER. Vascular leiomyoma of the oral cavity. Clinical, histopathological and immunohistochemical characteristics. Presentation of five cases and review of the literature. Med Oral Patol Oral Cir Bucal 2008 Aug 1;13(8):E483-E488.
- Giles AD, Gosney MB. Oral angiomyoma: a case report. Br J Oral Surg 1982 Jun;20(2):142-6.
- Nehls V, Denzer K, Drenckhahn D. Pericyte involvement in capillary sprouting during angiogenesis in situ. Cell Tissue Res 1992 Dec;270(3):469-74.
- Gerhardt H, Betsholtz C. Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res 2003 Oct;314(1):15-23.
- Scheper MA, Nikitakis NG, Meiller TF. A stable swelling of the hard palate. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Oct;104(4):461-4.