Iranian Journal of Pathology

Relationships of Serum Level of High- Sensitivity C- Reactive Protein (hs- CRP) and White Blood Cell (WBC) Count with Gamma- Glutamyltransferase among Iranian Healthy Adults

Document Type : Original Research

Authors

Alireza Abdollahi 1
Saeed Shoar 2

1 Dept. of Pathology, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

2 Development Association for Clinical Study (DACS), Student Scientific Research Center (SSCR), Tehran University of Medical Sciences, Tehran, Iran

Abstract
Background & Objective: There are many common infections and inflammations among people over the world. This demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. In the present study, we aimed to find any potential correlation between serum levels of GGT and CRP- Q and/or hs- CRP and WBC count as the well- known markers of inflammation in human body.
Materials and Methods: Through a cross- sectional study, serum levels of CRP-Q, hs- CRP, and GGT, in addition to WBC count were measured in 1,500 healthy people, referred to Blood Transfusion Organization from across the country. Data were analyzed after the patients were checked by physical examination for ruling out the presence of any inflammation or other illness. Serum levels of GGT, CRP- Q, hs- CRP, and WBC count were analyzed by SPSS for windows version 16.
Results: Analysis showed a positive linear correlation between CRP- Q and hs- CRP with GGT also confirmed by non- parametric tests.
Conclusion: Serum GGT may be an inflammatory index and a useful marker in approaching to inflammatory diseases.
 

Keywords

Gamma Glutamyltransferase
C- Reactive Protein
White Blood Cell Count
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Iranian Journal of Pathology
Volume 7, Issue 4 - Serial Number 4
Autumn 2012
Pages 209-214

  • Receive Date 13 September 2011
  • Accept Date 07 February 2012

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