Iranian Journal of Pathology

Malignant Pleomorphic Adenoma (Malignant Mixed Tumor) of the Minor Salivary Glands

Document Type : Case Reports

Authors

Afsaneh Rajabiani1 1
Fatemeh Kamrani Kanafi 1
Naser Kamalian 1
Saeed Shoar 2
Alireza Abdollahi 2
Sara Sheikhbahaei 2

1 Dept. of Pathology, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

2 Dept. of Pathology, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Abstract
Salivary  gland  tumors  accounts  for  less  than  1%  of  all  tumors.  Minor  salivary  gland  tumors (MSGTs) are uncommon and make up about 10% of all salivary gland neoplasms. The clinical and histopathological distribution of these tumors vary geographically. A case of a 38 yr old man with a minor salivary gland mass at chin region isreported here. The tumor invaded into the anterior surface of the mandible bone and the surrounding soft tissues. The tumor was resected completely with a safe surgical margin of soft tissue and adjacent bone. Histologically, the tumor is characterized by a biphasic pattern, composed of admixture of epithelial and stromal components, associated with cytological atypia and prominent mitoses. The stromal elements are myxoid, chondroid, and osteoid. The chondroid component is more abundant and shows more atypical changes.  Overall,  the  findings  were  interpreted  as  malignant  pleomorphic  adenoma  of  minor salivary glands of buccal mucosa.
 

Keywords

Malignant Mixed Tumor
Minor Salivary Gland
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Iranian Journal of Pathology
Volume 8, Issue 3 - Serial Number 3
Summer 2013
Pages 189-193

  • Receive Date 05 February 2012
  • Accept Date 02 October 2012

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