Iranian Journal of Pathology

Microbial and Antibiotic Susceptibility Profiles among Pleural Effusion Exudative Samples

Document Type : Original Research

Authors

Alireza Abdollahi 1
Saeed Shoar 2
Hiva Saffar 1
Hana saffar 1
Azita Yazdi 1

1 Dept. of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

2 evelopment Association for Clinical Study (DACS), Student Scientific Research Center (SSCR), Tehran University of Medical Sciences, Tehran, Iran

Abstract
 
Background and Objectives:Infection of pleural fluid is a common disease and because of antibiotic administration, the microbiology of this fluid has changed. The aim of this study was to determine the common bacteria and suitable antibiotics for treatment in pleural effusion (PE).
Materials and Methods: In this cross sectional study, 1210 samples with exudative features were cultured for possible growth of microbial pathogens and then examined for antibiotics sensitivity. Samples’ characteristics were then analyzed according to the age and sex difference.
Results: Among 1210 exudative pleural effusions, 38.2% were obtained from females and 61.8% from males. Of 142 pleural fluid samples, 11.7% had a positive culture. Aerobic gram negative organism was the most common type among the other samples with a prevalence of 52% followed by aerobic gram positive (25.3%), non- aerobic gram negative (15.7%), non- aerobic gram positive (6.2%) and fungi (0.8%). E. coli, Staphylococcus Aureus and Acinetobacter baumannii were the most common types of organism among adult population.
Conclusion:Aerobic gram positive bacteria had the highest prevalence among the pathogens, and cephalosporins, aminopenicillins and β-lactams were the most effective antibiotics for their treatment.
 

Keywords

Pleural effusion
Bacterial infection
Bacterial Sensitivity Test
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  • Receive Date 03 January 2013
  • Accept Date 05 May 2013

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