Iranian Journal of Pathology

The Sheep’s Urinary Bladder Matrix as a Potent Biological Materials Resource -an Ultrastructural Study

Document Type : Original Research

Authors

Bahare Zihayat 1
Mohsen Basiri 2
Farzad Doostishoar 1
Majid Asadi-Shekaari 2

1 Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran

2 Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran

Abstract
 
Background and Objectives: Biological scaffold resources composed of extracellular matrix (ECM) have been shown to make easy the practical remodeling of various tissues in both animal and human studies. The goal of current study was to make sheet form of ECM from sheep’s urinary bladder.
Methods: ECM was extracted from Sheep’s urinary bladder according to standard method. Scanning electron microscopy (SEM) was applied in order to analyze the ultrastructure of the extracted matrix.
Results: Matrix was formed by irregular and fiber like particles.
Conclusion: Sheep’s urinary bladder matrix may be used as an accessible and suitable source of ECM extraction.
 

Keywords

Extracellular matrix
Sheep
Scanning electron microscopy
Urinary bladder
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Iranian Journal of Pathology
Volume 9, Issue 2 - Serial Number 2
Spring 2014
Pages 113-116

  • Receive Date 11 June 2013
  • Accept Date 21 August 2013

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