Iranian Journal of Pathology

Primary Malignant Melanoma of the Gastrointestinal Tract: Report of Two Cases

Document Type : Case Reports

Authors

Akbar Safaei 1
Seyed Masood Tabib 2
Mohamad Reza Farzaneh 1
Jahanbanoo Shahryari 3
Mohamad Bahmaniar 4

1 Dept. of Pathology, Molecular Pathology and Cytogenetic Ward, Shiraz University of Medical Sciences, Shiraz, Iran

2 Internal ward, Boushehr University of Medical Sciences, Boushehr, Iran

3 Dept. of Pathology, Molecular Pathology and Cytogenetic Ward, Shiraz University o Medical Sciences, Shiraz, Iran

4 Dept. of Pathology, Fatemeh Zahra Hospital, Boushehr University of Medical Sciences, Boushehr, Iran.

Abstract
Although gastrointestinal involvement by metastatic malignant melanoma is common but primary gastrointestinal (GI) melanoma has been reported in rare cases. In this study we report two cases of primary gastrointestinal malignant melanoma that one of them is a known case of neurofibromatosis type 1(NF1). Both cases showed no evidence of any lesions in skin and eye. Malignant melanoma of GI tract in patient with neurofibroma is reported with hypothesis of a possible relation between two pathologies. Both primary GI melanoma and combination of NF1 with primary GI melanoma are rare entities discussed in this article.

Keywords

Melanoma
Gastrointestinal tract
Neurofibromatosis
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Iranian Journal of Pathology
Volume 9, Issue 3 - Serial Number 3
Summer 2014
Pages 213-218

  • Receive Date 30 March 2013
  • Accept Date 18 October 2013

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