Iranian Journal of Pathology

International Academy of Cytology Yokohama System for Reporting Breast Cytology and the ACR Breast Imaging Reporting and Data System (BIRADS): Are they Concordant?

Document Type : Original Research

Authors

Alka Yadav 1
Aparna Singh 2
Sonali Madaan 3
Mukta Pujani 2
Sujata Raychaudhuri 4
Charu Agarwal 2
Varsha Chauhan 2
Dipti Sidam 2
Jyoti Rajpoot 2
Garima Dhull 2
Cherry Bansal 5

1 Department of Pathology, The Uttar Pradesh University of Medical Sciences, Saifai, Etawah, UP, India

2 Department of Pathology, ESIC Medical College & Hospital, Faridabad, India

3 Department of Radiodiagnosis, ESIC Medical College & Hospital, Faridabad, India

4 Department of Pathology, ESIC PGIMSR, Basaidarapur, New Delhi, India

5 Department of Pathology, Dr. SS Tantia Medical College, Sriganganagar, India

https://doi.org/10.30699/ijp.2024.2028955.3300
Abstract
Background & Objective: Breast cancer is the leading cause of cancer deaths among women worldwide. Fine needle aspiration cytology (FNAC) and breast sonography have played a pivotal role in the characterization of a breast lump. The main objective of this study was to analyze the correlation between the International Academy of Cytology (IAC) Yokohama for Reporting Breast Fine Needle Aspiration Biopsies (FNAB) and breast imaging reporting and data system (BIRADS) for sonography along with histopathological correlation.
Methods: A total of 135 FNAC specimens were categorized according to the IAC Yokohama system and BIRADS reporting system and their correlation with histopathology wherever possible to calculate the risk of malignancy (ROM).
Results: According to IAC Yokohama categorization, the cases in categories I, II, III, IV, and V were 1,78,8,6 and 42, respectively. Akin to cytology, most of the cases were assigned BIRADS score two followed by score 6, with the Pearson’s correlation coefficient between the IAC Yokohama system for reporting breast cytology and BIRADS scoring system of 1.957 with a P-value < 0.001 (strong correlation). The sensitivity, specificity, PPV, NPV, and DA of FNAC with category III assumed as malignant were 98.9%, 85%, 76.1%, 99.3%, and 89.5%, respectively. Histopathological correlation was available for 90 cases. The ROM for categories II, III, IV, and V was 5.6%,37.5%,100%, and 100%, respectively.
Conclusion: IAC Yokohama system of reporting breast cytopathology and BIRADS serves as a common language of communication between pathologists and clinicians and aid in better stratification of the lesions. Both FNAC (minimally invasive) and ultrasound (non-invasive imaging technique) are diagnostic tools that complement each other for patient diagnosis and management.

Keywords

IAC Yokohama
breast cytology
BIRADS
ROM
FNAC

Subjects

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Iranian Journal of Pathology
Volume 19, Issue 4
Autumn 2024
Pages 400-407

  • Receive Date 14 May 2024
  • Revise Date 03 June 2024
  • Accept Date 07 June 2024

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