Document Type : Case Reports
Authors
- Nahid Ghanbarzadeh 1
- Mohammad Nadjafi-Semnani 2
- Zohreh Azarkar 3
- Fatemeh Haghighi 4
- Ali Nadjafi-Semnani 5
1 Dept. of Gynecology and Obstetrics, Birjand University of Medical Sciences, Birjand, Iran
2 Dept. of Urology, Birjand University of Medical Sciences, Birjand, Iran
3 Dept. of Infectious Disease, Birjand University of Medical Sciences, Birjand, Iran
4 Dept. of pathology, Birjand University of Medical Sciences, Birjand, Iran
5 Tehran University of Medical Sciences, Tehran, Iran
Abstract
Primary ovarian carcinoid tumors of the ovary are rare and represent less than 0.1% of ovarian malignancy. One of its subtypes is the strumal carcinoid in which the thyroid tissue is seen in intimate association with carcinoid tumor. We here report a 47-year-old woman with strumal carcinoid of the right ovary presented with cessation of menstrual periods in the past 3 months and was referred due to a possible menopause-related symptom. A firm pelvic mass was found in physical examination and a large mass (20 × 15 × 8 cm) in the right ovary was reported in ultrasound evaluation. The spiral CT scan reported masses in both ovaries. The patient underwent total abdominal hysterectomy plus bilateral salpingo-oophorectomy. The pathological evaluation revealed strumal carcinoid tumor with thyroid tissue in right ovary and benign cystic teratoma in left ovary. Our case was alive at 8 years after the operation with no disease recurrence.
Keywords
- Matsuda K, Maehama T, Kanazawa K. Strumal carcinoid tumor of the ovary: a case exhibiting severe constipation associated with PYY. Gynecol Oncol. 2002;87(1):143-5.
- Yamaguchi M, Tashiro H, Motohara K-i, Ohba T, Katabuchi H. Primary strumal carcinoid tumor of the ovary: A pregnant patient exhibiting severe constipation and CEA elevation. Gynecologic Oncology Case Reports. 2013;4:9-12.
- Hayashi T, Haba R, Kushida Y, Kadota K, Katsuki N, Miyai Y, et al. Cytopathologic characteristics of the primary strumal carcinoid tumor of the ovary: A case report with emphasis on differential diagnostic considerations. Diagn Cytopathol. 2013;41(9):812–16.
- Bai X, Li N, Wang F, Li S, Yu Q. Primary ovarian trabecular carcinoid tumor: a case report and literature review. Arch Gynecol Obstet. 2010;282(4):407-11.
- Somak R, Shramana M, Vijay S, Nita K. Primary carcinoid tumor of the ovary: a case report. Arch Gynecol Obstet. 2008;277(1):79-82.
- Roth LM, Talerman A. The enigma of struma ovarii. Pathology. 2007;39(1):139-46.
- Kawano K, Ushijima K, Fujimoto T, Komai K, Kamura T. Peptide YY producing strumal carcinoid of the ovary as the cause of severe constipation with contralateral epithelial ovarian cancer. J Obstet Gynaecol Res. 2007;33(3):392-6.
- Matsunami K, Takagi H, Ichigo S, Murase T, Ikeda T, Imai A. Peptide YY producing strumal carcinoid tumor of the ovary. Eur J Gynaecol Oncol. 2011;32(2):201-2.
- Ashton MA. Strumal carcinoid of the ovary associated with hyperinsulinaemic hypoglycaemia and cutaneous melanosis. Histopathology. 1995;27(5):463-7.
- Gorin I, Sastre-Garau X. Strumal carcinoid tumor of the ovary. J Clin Oncol. 2008;26(16):2780-1.
- Robboy SJ, Scully RE. Strumal carcinoid of the ovary: an analysis of 50 cases of a distinctive tumor composed of thyroid tissue and carcinoid. Cancer. 1980;46(9):2019-34.
- Soga J, Osaka M, Yakuwa Y. Carcinoids of the ovary: an analysis of 329 reported cases. J Exp Clin Cancer Res. 2000;19(3):271-80.
- Rabban JT, Lerwill MF, McCluggage WG, Grenert JP, Zaloudek CJ. Primary ovarian carcinoid tumors may express CDX-2: a potential pitfall in distinction from metastatic intestinal carcinoid tumors involving the ovary. Int J Gynecol Pathol. 2009;28(1):41-8.
- Kopf B, Rosti G, Lanzanova G, Marangolo M. Locally advanced ovarian carcinoid. J Exp Clin Cancer Res. 2005;24(2):313-6.