Iranian Journal of Pathology

Pathological Examination of the Placenta in COVID-19–Positive Mothers: A Short Communication

Document Type : Short Communication

Authors

Sedigheh Hantoushzadeh 1
Roya Saeednejad 1
Mamak Shariat 1
Raheleh Moradi 2

1 Institute of Family Health, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran

2 Institute of Family Health, Breastfeeding Research Center, Tehran University of Medical Sciences, Tehran, Iran

https://doi.org/10.30699/ijp.2023.551018.2860
Abstract
Background & Objective: It was declared that COVID-19 might be more severe in symptomatic pregnant patients. This study was conducted to examine the pathological indices of the placenta in pregnant women who were diagnosed with COVID-19.
Methods: A total of 20 COVID-19–positive mothers were enrolled in this study. Detailed placental pathology findings were compared between subjects based on the history of abortion or occurrence of preterm delivery, hypertension, and diabetes.
Results and Conclusion: Intervillositis was the most frequent abnormality of the placenta. There was also a significant association between abortion history and maternal vascular malperfusion (MVM; P=0.02). The placental abnormalities were found to be increased in women with COVID-19, regardless of maternal comorbidities. Further studies are needed to compare the placental pathology between COVID-19–positive women and healthy women. 

Keywords

COVID-19
Pathology
Placenta
Pregnancy

Subjects

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Iranian Journal of Pathology
Volume 18, Issue 2
Spring 2023
Pages 217-220

  • Receive Date 04 April 2022
  • Revise Date 26 May 2022
  • Accept Date 25 March 2023

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