Iranian Journal of Pathology

Effect of Phototherapy on Serum Level of Calcium, Magnesium and Vitamin D in Infants with Hyperbilirubinemia

Document Type : Short Communication

Authors

Sahar Shahriarpanah 1
Fatemeh Haji Ebrahim Tehrani 2
Ali Davati 3
Iman Ansari 1

1 Medical Students Research Committee, Shahed University, Tehran, Iran

2 Dept of Pediatrics, Faculty of Medicine, Shahed University, Tehran, Iran

3 Dept of Health & Social Medicine, Faculty of Medicine, Shahed University, Tehran, Iran

Abstract
Background and Objective: Phototherapy is one of the therapy methods for jaundice caused by hyperbilirubinemia. Vitamin D and bilirubin have two distinct routes of metabolism yet part of their syntheses is common in the liver and thus they may influence each other’s synthesis. One of the consequences of phototherapy not previously studied in detail is hypocalcaemia and hypomagnesaemia. The current study aimed at investigating the effect of phototherapy on serum level of calcium, magnesium, and vitamin D.
Methods: The current semi-experimental investigation was conducted on 50 term infants with jaundice that had phototherapy indication. Bilirubin, calcium, magnesium, and vitamin D were measured in their blood samples at admission and then 48 hours after beginning the phototherapy. Data were analyzed with SPSS version 16 using paired-samples t test.
Results and Discussion: The serum calcium was 9.85 mg/dL before phototherapy and significantly decreased after it (9.51 mg/dL) (P<0.001). Also, the mean serum magnesium was 2.21 mg/dL before phototherapy and significantly decreased after it (2.06 mg/dL) (P=0.047). The mean of serum vitamin D significantly increased after phototherapy (before 17.44 mg/dL and after 21.77 mg/dL) (P<0.0001). The current study showed that phototherapy could decrease the level of calcium and magnesium and increase the level of vitamin D.

Keywords

Phototherapy
Hyperbilirubinemia
Calcium
Magnesium
Vitamin D

Subjects

  • Receive Date 01 February 2017
  • Revise Date 03 May 2017
  • Accept Date 18 August 2018

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