Iranian Journal of Pathology

Placental Mesenchymal Dysplasia With Normal Fetus: A Rare Case Report

Document Type : Case Reports

Authors

Subrata Pal 1
Kingshuk Bose 2
Palash Ch Mondal 3
Srabani Chakrabarti 4
Mrinal Sikder 5

1 Dept. of Pathology, College of Medicine and Sagore Dutta Hospital. Kolkata, India

2 Dept. of Pathology, Bankura Sammilani Medical College, Bankura, India.

3 Dept. of Gynaecology and Obstretics, Bankura Sammilani Medical College, Bankura, India

4 Dept. of Pathology, Culcutta National Medical College, Kolkata, India

5 Dept. of Pathology, R G Kar Medical College, Kolkata, India

https://doi.org/10.30699/ijp.2017.25856
Abstract
Placental mesenchymal dysplasia (PMD) is a rare benign placental abnormality. It is characterized by hydropic degeneration of stem villi, placentomegaly, and increased maternal serum alpha-fetoprotein(AFP). It can be associated with different congenital abnormalities, karyotype abnormalities, and feto-maternal morbidities. It is difficult to differentiate PMDfrom partial mole, complete mole with twin pregnancy in ultrasound, and in macroscopic examination. The current paper presentsa rare case of placental mesenchymal dysplasia in a young primigravida mother who delivered a normal fetus withnormal karyotype. 

Highlights

  • Placental mesenchymal dysplasia is a very rare benign condition of placenta.
  • Ultrasound and gross examinations closely mimic partial mole.
  • Histopathology of the placenta is a definite methodofdiagnosis.
  • It may be associated with various congenital abnormalities.
  • If prenatal diagnosis is possible, close monitoring is necessary. 

Keywords

Placental mesenchymal dysplasia (PMD)
normal fetus
partial mole

Subjects

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Iranian Journal of Pathology
Volume 12, Issue 3
Summer 2017
Pages 307-310

  • Receive Date 14 June 2016
  • Revise Date 22 February 2017
  • Accept Date 15 June 2017

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