Document Type : Case Reports


1 Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Surgery, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

3 Department of Pathology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

4 Medical Student, Student Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran

5 Department of Nursing, Islamic Azad University, Tabas Branch, Tabas, Iran

6 Department of Nursing, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran


Novel coronavirus disease 2019 (COVID-19) as a potential health risk factor continues to spread throughout the world. Although common symptoms include headache and respiratory symptoms, some studies have suggested that COVID-19 may cause coagulation disorders and thrombolytic events, disrupt blood flow to the visceral organs, and cause some complications such as mesenteric ischemia. The authors reported four cases of acute mesenteric ischemia associated with COVID-19 confirmed in patients hospitalized in Imam Reza Hospital (a COVID-19 referral center in Mashhad University of Medical Sciences, Mashhad, Iran). The authors described the pathological findings that may be associated with this infection. The authors collected clinical data, imaging, microscopic, and operative findings of four patients with severe COVID-19 infection and evidence of intestinal necrosis. These four cases that all had severe COVID-19 pneumonia simultaneously showed intestinal necrosis during the infection process, indicating a relationship between coronavirus and mesenteric vascular events. Physicians should be aware of thrombosis symptoms in the digestive system in patients with severe COVID-19 disease.


Main Subjects

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