Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Head and Neck Pathology
The Frequency of Human Papillomavirus Positivity in Iranian Patients with Head and Neck Squamous Cell Carcinoma

Mitra Rezaei; Mahboobeh Karimi-Galougahi; Azin Kheradmand; Mihan Pourabdollah Toutkaboni; Hassan Mir Mohammad Sadeghi; Alireza Abdollahi; Amirnader Emami Razavi; Ali Safavi Naini; Farahnaz Bidari- Zerehpoosh

Volume 16, Issue 1 , January 2021, , Pages 20-26


  Background & Objective: Human papillomavirus (HPV) has been associated with prognosis in patients with head and neck squamous cell carcinoma (HNSCC). Similar to the global studies, different prevalence rates of this viral infection have been reported in Iran. Therefore, we aimed to report the prevalence ...  Read More

Molecular Pathology
Investigation of HER-2 expression and its Correlation with clinicopathological parameters and overall survival of esophageal squamous cell carcinoma patients

Mitra Heidarpour; Mehran Taheri; Ali Akhavan; Parvin Goli; Amirhosein Kefayat

Volume 15, Issue 4 , October 2020, , Pages 274-281


  Background & Objective: Human epidermal growth factor receptor 2 (HER-2) exhibits a vast range of expression in esophageal squamous cell carcinoma (ESCC) patients as a biomarker. This paper aimed to investigate HER-2 expression and clinicopathological parameters of esophageal SCC. Methods: HER-2 ...  Read More

Oral Pathology
Detection of Apoptosis in Leukoplakia and Oral Squamous Cell Carcinoma using Methyl Green Pyronin and Hematoxylin and Eosin

Pooja Sharma; Anjali Narwal; Mala Kamboj

Volume 15, Issue 3 , July 2020, , Pages 189-196


  Background & Objective: Cell population and turnover are controlled by a balance between cell proliferation and apoptosis. Detection of apoptosis in oral cancer contributes to its better prognosis and improved management. This study aimed to quantify apoptotic cells in leukoplakia and oral squamous ...  Read More

Association of Some High-Risk Mucosal Types of Human Papillomavirus with Cutaneous Squamous Cell Carcinoma in an Iranian Population

Hassan Ehteram; Mohaddeseh Sadat Mousavian; Tahereh Mazoochi; Tahereh Khamehchian; Mohammad Karimian

Volume 14, Issue 4 , October 2019, , Pages 313-316


  Background & Objective: Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer that may be caused by Human papillomavirus (HPV), especially in immunosuppressed patients. However, the role of the mucosal types of HPV in SCC patients with normal immunity has not been extensively ...  Read More

Oral Pathology
Correlation of vascularization and inflammation with severity of oral leukoplakia

Fatemeh Mashhadiabbas; Masoume Fayazi-Boroujeni

Volume 12, Issue 3 , July 2017, , Pages 225-230


  Background & objective: Changes in submucosal vascularization and inflammation, determined by immunohistochemistry staining, were shown to be correlated with the development of dysplasia and invasiveness of epithelial cells in premalignant and malignant lesions. This study evaluated changes in sections ...  Read More

The Prevalence of Human Papilloma Virus in Squamous Cell Carcinoma of Oral Tongue

Mohamad Javad Ashraf; Shahla Hosseini; Ahmad Monabati; Behnaz Valibeigi; Bijan Khademi; Elham Abedi; Negar Azarpira

Volume 12, Issue 2 , April 2017, , Pages 144-149


  Background and objective:  Oral tongue Squamous Cell carcinoma (SCC) commonly involves males between the sixth to eighth decades of life. Major risk factors are tobacco usage and alcohol consumption. The increasing number of patients developing oral tongue cancer without these well-known risk factors ...  Read More

The Usefulness of CD10 in Distinguishing between Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

Shahram Sabeti; Farhad Malekzad; Nastaran Neishaboori; Mihan Pourabdollah Toutkaboni; Farahnaz Bidarizerehpoosh

Volume 9, Issue 4 , October 2014, , Pages 245-250

  Background & Objectives:  CD10 is a cell surface enzyme with metalloendopeptidase activity, also known as Common Acute Lymphoblastic Leukaemia Antigen, which mainly serves as a marker for acute lymphoblastic leukemia (ALL). To date and to the best of our knowledge, only few comparative immunohistochemical ...  Read More

Tongue Squamous Cell Carcinoma: A Clinical Study

Hamidreza Azimi; Saeedeh Khajehahmadi; Amin Rahpeyma

Volume 9, Issue 1 , January 2014, , Pages 28-32

    Background and Objectives: Squamous cell carcinoma of the tongue (SCCOT) is the most common malignant neoplasm in oral cavity. At the time of the diagnosis of SCCOT regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. ...  Read More

Primary Intraosseous Carcinoma of the Maxilla

Maryam Alsadat Hashemipour; Shahrzad Adhami; Behroz Mozafari; Fatemeh Ahmadi Motemail

Volume 6, Issue 3 , June 2011, , Pages 158-163

  A primary intraosseous carcinoma (PIOC) is a squamous cell carcinoma arising within the  jawbone andshould be differentiated from a malignant ameloblastoma.  It  is not due to arising from an odontogenic cyst or tumor. The possibility of the lesion being  a metastasis fromanotherprimary ...  Read More

Evaluation of Cyclin D1 Expression in Esophageal Squamous Cell Carcinoma and its Effect on Response Rate to Neo- adjuvant Chemoradiotherapy

Fatemeh Homaei Shandiz; Mohammad-Reza Ghavam Nassiri; Fatemeh Varshoee Tabrizi; Mohammad Khagedaloee; Kamran Ghafarzadegan

Volume 5, Issue 1 , January 2010, , Pages 9-13

    Background and Objective: Esophageal cancer especially squamous cell carcinoma (SCC) is one of the most common gastro intestinal malignancies in north part of Iran (Khorasan). The standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. Then, the oncologists ...  Read More

Clinicopatholgic Parameters Associated With Regional Lymph Node Metastasis In Oral Squamous Cell Carcinoma: A Retrospective Study

Maryam Khalili; Zahra Alyani

Volume 3, Issue 3 , June 2008, , Pages 140-145

    Background and Objective: Oral cancer accounts for less than 3% of all cancers. Despite recent improvement in diagnostic and treatment methods, the overall survival of the disease is unfavorable. Several studies have been performed to assess factors influencing lymph node metastasis and prognosis. ...  Read More

Ocular Tumors In Iran: A 10-Year Histopathological Study On 384 Cases Of Enucleation

Seyed Ali Ahmadi; Fahimeh Asadi Amoli; Katayoun Gohari Moghaddam

Volume 3, Issue 3 , June 2008, , Pages 151-156

    Background and Objective: The frequency and pattern of eye neoplasms differ in various geographic areas. Our aim was to determine the distribution of patient age, gender, ocular tumor origin, location and histological type in our region. Materials and Methods: In this cross-sectional study, ...  Read More

The Effect Of P53 Protein Over-Expression And Its Clinical Features On The Response To Preoperative Chemoradiotherapy Of Esophageal Squamous Cell Carcinoma

Mehdi Seilanian Toosi; Mohammad Reza Ghavam Nasiri; Kamran Ghafarzadegan; Azar Fani Pakdel; Roham Salek; Kazem Anvari

Volume 3, Issue 1 , January 2008, , Pages 5-10

  Background and Objective: P53 is a suppressive gene that plays a key role in DNA repair and apoptosis. The purpose of this study was to investigate the effect of P53 protein over-expression and some clinicopathological factors on the esophageal squamous cell carcinoma (SCC) response to neoadjuvant chemoradiotherapy. ...  Read More

Cytodiagnosis of Cutaneous Basal and Squamous Cell Carcinoma

Nourieh Sharifi; Mohammad Javad Yazdanpanah

Volume 2, Issue 3 , June 2007, , Pages 97-99

  Background and Objective: Cutaneous cytology is the study of scraping or smears obtained from skin lesions. Although not commonly employed, cutaneous cytology has been a useful tool for clinicians due to simplified procedures and high sensitivity and specificity of presurgical clinical diagnosis of common ...  Read More

Evaluation of Diagnostic Values of EMA and Ber-Ep4 in Distinction between Basal Cell Carcinoma and Squamous Cell Carcinoma of the Skin

Parvin Rajabi; Mohammad Aboutalebdokht; Mitra Heidarpour; Ali Asilian; Fatemeh Rajabi

Volume 2, Issue 1 , January 2007, , Pages 7-10

  Background and Objective: Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are two common tumors of the skin. In some cases, distinction between BCC and SCC can be difficult. This study aimed to clarify this uncertainty through immunohistochemical analysis. In this respect, epithelial membrane ...  Read More