Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Higher Viral Load of Polyomavirus Type BK but not JC among Renal Transplant Recipients in Comparison to Donors

Samaneh Abolbashari; MohammadTaghi Shakeri; Maryam Hami; Aida Gholoobi; Amin Hooshyar Chechaklou; Mohammad Sadegh Damavandi; Aref Movaqar; Razieh Yousefi; Zahra Meshkat; Saeedeh Hajebi Khaniki

Volume 17, Issue 1 , January 2022, , Pages 8-14


  Background & Objective: Polyomaviruses types BK and JC and Cytomegalovirus (CMV) have been shown to be related to kidney transplantation complications. This study aimed to assess the prevalence of these viruses in patients receiving kidney transplantation.Methods: This cross-sectional study was performed ...  Read More

Designing and Construction of a Cloning Vector Encoding mtb32C and mpt51 Fragments of Mycobacterium Tuberculosis as a DNA Vaccine Candidate

Faria Hasanzadeh Haghighi; Ehsan Aryan; Mohammad Derakhshan; Aida Gholoobi; Zahra Meshkat

Volume 13, Issue 4 , October 2018, , Pages 403-407

  Background & objective:  Tuberculosis (TB) remains a major cause of death around the world. Bacillus Calmette Guérin (BCG) is the only vaccine used in TB prevention that has a protective effect in children, but its effectiveness declines in adults. Design and development of new vaccines ...  Read More

Investigation of the rpoB Mutations Causing Rifampin Resistance by Rapid Screening in Mycobacterium Tuberculosis in North-East of Iran

Amir Tajbakhsh; Faezeh Ghasemi; Seyedeh Zohre Mirbagheri; Mastoureh Momen Heravi; Mehdi Rezaee; Zahra Meshkat

Volume 13, Issue 4 , October 2018, , Pages 429-437

  Background and Objectives: The incidence of rifampin-resistant strains of Mycobacterium tuberculosis has attracted more attention than the tuberculosis infection due to laborious treatment and control. Recognizing the Mycobacterium tuberculosis genotypes involving in drug resistance via multiplex PCR, ...  Read More

Development of Preventive Vaccines for Hepatitis C Virus E1/E2 Protein

Faezeh Ghasemi; Majid Ghayour Mobarhan; Hamed Gouklani; Zahra Meshkat

Volume 13, Issue 2 , April 2018, , Pages 113-124


  Hepatitis C virus (HCV) is responsible for a vast majority of liver failure cases. HCV is a kind of blood disease appraised to chronically infect 3% of the worlds’ population causing significant morbidity and mortality. Therefore, a complete knowledge of humoral responses against HCV, resulting ...  Read More

The Frequency of qnr Genes in Extended-Spectrum β-lactamases and non-ESBLs Klebsiella pneumoniae Species Isolated from Patients in Mashhad, Iran

Nafiseh Izadi; Mahboubeh Naderi Nasab; Elnaz Harifi Mood; Zahra Meshkat

Volume 12, Issue 4 , December 2017, , Pages 377-383


  Background and Objectives: Since the fluoroquinolones are the broad-spectrum antibiotics, they affect both Gram-negative and Gram-positive bacteria. These antibiotics are widely prescribed by physicians. As a result, some bacteria, especially Enterobacteriaceae, have shown a resistance to this family ...  Read More

Comparison of Interferon-Gamma (IFNG) +874 T/A Single Nucleotide Polymorphism in Hepatitis C Virus Infected Patients and Non-Infected Controls in Mashhad, Iran

Sina Rostami; Alireza Pasdar; Sina Gerayli; Hamed Hatami; Samaneh Sepahi; Fatemeh Nategh; Mojtaba Meshkat; Seyed Mousalreza Hoseini; Mitra Ahadi; Hamid Reza Sima; Hasan Vosughinia; Mohammad Reza Sarvghad; Abbas Esmaeelzade; Hosein Nomani; Homan Mosanan Mozafari; Fariba Rezai Talab; Mohammad Taghi Shakeri; Zahra Meshkat

Volume 12, Issue 3 , July 2017, , Pages 248-256


  Background and Objectives: Interferon-gamma is an important cytokine, which facilitates immunity against intracellular pathogens. Several factors, including genetic variations of cytokine-producing genes have been shown to influence the progression and severity of Hepatitis C virus (HCV) infection. Methods: ...  Read More

Designing and Development of a DNA Vaccine Based On Structural Proteins of Hepatitis C Virus

Roghayeh Teimourpour; Amineh Sadat Tajani; Vahid Reza Askari; Sina Rostami; Zahra Meshkat

Volume 11, Issue 3 , July 2016, , Pages 222-230

  Background: Hepatitis C virus (HCV) infection is one of the most prevalent infectious diseases responsible for high morbidity and mortality worldwide. Therefore, designing new and effective therapeutics is of great importance. The aim of the current study was to construct a DNA vaccine containing ...  Read More

Designing and construction of a DNA vaccine encoding tb10.4 gene of Mycobacterium tuberculosis

Samira Rashidian; Roghayeh Teimourpour; Zahra Meshkat

Volume 11, Issue 2 , April 2016, , Pages 112-119

  Background: Tuberculosis (TB) remains as a major cause of death around the world. Construction of a new vaccine against tuberculosis is an effective way to control it. Several vaccines against this disease have been developed. The aim of the present study was to cloning of tb10.4 gene in pcDNA3.1+ plasmid ...  Read More

Developing Michigan Cancer Foundation 7 Cells with Stable Expression of E7 Gene of Human Papillomavirus Type 16

Faezeh Ghasemi; Sina Rostami; Maryam Sadat Nabavinia; Zahra Meshkat

Volume 11, Issue 1 , January 2016, , Pages 41-46

  Background: Human papillomavirus (HPV) is responsible for the development of cervical neoplasia.  Infection with human papillomavirus type 16 (HPV-16) is a major risk factor for the development of cervical cancer. The virus encodes three oncoproteins (E5, E6 and E7), of which, the E7 oncoprotein ...  Read More

Frequency of Human Papillomavirus Genotypes 6, 11, 16, 18 And 31 in Paraffin-Embedded Tissue Samples of Invasive Breast Carcinoma, North-East of Iran

Masoumeh Salehpour; Naser Tayyebi Meibodi; Roghayeh Teimourpour; Adel Ghorani-Azam; Samaneh Sepahi; Sina Rostami; Zahra Meshkat

Volume 10, Issue 3 , July 2015, , Pages 192-198


  Background &Objective: Breast cancer is the most common female malignancy. Detection of DNA of human papillomaviruses (HPVs) in breast carcinomas suggests that the virus may play a role in the pathogenesis of this disease. The aim of this study was to evaluate the frequency of HPVs genotypes 6, 11, ...  Read More

Prevalence of TEM and SHV Genes in Clinical Isolates of Klebsiella Pneumonia From Mashhad, North- East Iran

Nafiseh Izadi; Mahboubeh Naderi Nasab; Elnaz Harifi Mood; Zahra Meshkat

Volume 9, Issue 3 , July 2014, , Pages 199-205

  Background & Objectives:Extended-spectrum-B-lactamase (ESBL)-producing strains of Klebsiella Pneumoniaare an important cause of many serious infections in hospitalized and nonhospitalized patients and delayed treatment of these infections in crease chance of death in patients. This study was performed ...  Read More

Eight-year Study of Mycobacterium tuberculosis in Mashhad, Northeast of Iran

Reza Akhavan; Zahra Meshkat; Mehrangiz Khajekaramadini; Mojtaba Meshkat

Volume 8, Issue 2 , April 2013, , Pages 73-80

  Background & Objectives: Tuberculosis is one of the greatest health problems in Iran. The distribution of the disease is not equal in all parts of the country. The aim of this study was to evaluate the frequency of positive results for Mycobacterium tuberculosis in samples referred to an academic ...  Read More

Construction a DNA Vaccine Containing Human Papillomavirus Type 16 Early Genes as a Potential Vaccine for Cervical Cancer Prevention and Therapy

Zahra Meshkat; Hessam Mirshahabi; Hoorieh Soleimanjahi; Zuhair Mohamad Hassan

Volume 4, Issue 2 , April 2009, , Pages 65-70

    Background and Objectives: Some of the human papillomaviruses (HPVs) can infect genital tracts and are sometimes associated with anogenital tract cancers. HPVs induced cervical cancers through the expression of E6 and E7 genes by inactivating the tumor suppressor proteins. In this study, E6 and ...  Read More