Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Review Article
Secondary Use of Laboratory data: Potentialities and Limitations

Massoud Hajia

Volume 14, Issue 3 , August 2019, Pages 188-192


  Clinical databases have been developed in recent years especially during the course of all medical concerns including laboratory results. The information produced by the diagnostic laboratories have great impact on health care system with various secondary uses. These uses are sometimes as publishing ...  Read More

Original Research Dermatopathology
Evaluation of Immunohistochemical Findings and Clinical Features associated with Local Aggressiveness in Basal Cell Carcinoma

Simin Shamsi meymandi; Shahriar Dabiri; Alireza ZeynadiniMeymand; Maryam Iranpour; Maryam Khalili; Sorour Alijani; Mahin Aflatoonian

Volume 14, Issue 3 , August 2019, Pages 193-196


  Background & Objective:Basal cell carcinoma (BCC) is classified into BCC1 or low risk (nodular, superficial type) and BCC2 or high risk (micronodular, morpheaform, infiltrative, and basosquamous types) based on clinical behavior. This study attempts to evaluate immunohistochemical (IHC) findings ...  Read More

Original Research Microbiology
The Prevalence of HPV Genotypes in Iranian Population: An Update

Mina Mobini Kesheh; Hossein Keyvani

Volume 14, Issue 3 , August 2019, Pages 197-205


  Background & Objective: Human papillomavirus (HPV) is the main cause of genital warts and some anogenital cancers in male and female subjects which is commonly transmitted by sexual contacts. The objective of this cross-sectional study was to examine the prevalence of HPV genotypes in 10,266 Iranian ...  Read More

Original Research Microbiology
Polymorphisms in Promoter Region of the Interferon - Gamma Receptor1 Gene and its Relation with Susceptibility to Brucellosis

Zahra Naseri; Nasrin Bahmani; Mohammad Yosef Alikhani; Seyed Hamid Hashemi; Ghodratollah Roshanaei

Volume 14, Issue 3 , August 2019, Pages 206-211


  Background & Objective: Brucellosis is one of the most prevalent bacterial zoonotic diseases which afflicts both humans and animals. Genetic factors play an important role in susceptibility to brucellosis. One of these factors is interferon-gamma (IFN-g), which is vital in the defense mechanism against ...  Read More

Original Research
Prostate Cancer with Intraluminal Inclusions: the Association of the Immunophenotype with Grade Score

Artem Piddubnyi; Anatolii M Romaniuk; Inna-Margaryta Radomychelski; Yuliia Moskalenko; Roman Moskalenko

Volume 14, Issue 3 , August 2019, Pages 212-222


  Background & Objective: To study the immunophenotype of prostate cancer (PC) with the presence and absence of intraluminal inclusions (IIn), depending on the grade score. Methods: A total of 30 PC samples with IIn (group E) and 30 PC samples without them (group C) were studied. These groups were ...  Read More

Original Research Breast Pathology
The Difference of Expression of 18 Genes in Axillary Invasion and Vascular Invasion Compared to Control Samples in Breast Cancer

Alireza Abdollahi; Sepideh Jahanian; Nima Hemmati; Hadiseh Mohammadpour

Volume 14, Issue 3 , August 2019, Pages 223-231


  Background & Objective: Recent studies from gene profiling have revealed some genes that are overexpressed in the epithelial-mesenchymal transition (EMT) process and are responsible for its initiation and activation resulting in tumor progression and metastasis. The present study aimed to assess ...  Read More

Original Research Breast Pathology
Vascular Mimicry Expression in Invasive Ductal Carcinoma; A New Technique for Prospect of Aggressiveness

Amir Hosein Jafarian; Melika Kooshkiforooshani; Abdolshakor Rasoliostadi; Nema Mohamadian Roshan

Volume 14, Issue 3 , August 2019, Pages 232-235


  Background & Objective: In vascular (vasculogenic) mimicry (VM), tumoral cells mimic the endothelial cells and form the extracellular matrix-rich tubular networks. It has been proposed that VM is more extensive in aggressive tumors. This study was designed to investigate the rate of VM expression ...  Read More

Original Research Immunology and Serology
IL-17 is Aberrantly Overexpressed Among Under-treatment Systemic Lupus Erythematosus Patients

Saeed Mohammadi; Sima Sedighi; Ali Memarian

Volume 14, Issue 3 , August 2019, Pages 236-242


  Background & Objective: Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic inflammatory immune response. Current therapies mostly rely on glucocorticoids which are accompanied by side-effects and mostly fail to achieve a favorable remission. Th17 subpopulation of T cells is ...  Read More

Original Research GI, Liver & Pancreas Pathology
Inter-observer Variability in Histomorphological Evaluation of Non-neoplastic Liver Biopsy Tissue and Impact of Clinical Information on Final Diagnosis in Shahid Beheshti University of Medical Sciences Affiliated Hospitals

Zeinab Kishani farahani; Mahsa Ahadi; Behrang Kazeminejad; Tahmineh Mollasharifi; Malihe Saber Afsharian; Amir Sadeghi; Farahnaz Bidari zerehpoosh; Elena Jamali; Niki Hasanzadeh; Abolfazl Movafagh; Arash Dehghan; Arsham Moradi; Afshin Moradi

Volume 14, Issue 3 , August 2019, Pages 243-251


  Background & Objective: Liver biopsy is the main method for grading and staging liver disorders, but the effects of clinical information and optimal biopsy specimen size on interpretation remain contentious. The aim of the study was to evaluate the impact of clinical information and quality of liver ...  Read More

Original Research Immunology and Serology
An Immunohistochemical Study of Cyclin D1 Expression in Astrocytic Tumors and its Correlation with Tumor Grade

Parvin Mahzouni; Fatemeh Taheri

Volume 14, Issue 3 , August 2019, Pages 252-257


  Background & Objective: Glioblastoma-multiforme is the high grade form of astrocytic tumors with a short survival time, which are the most common type of brain tumors. Therefore, finding new therapeutic options is essential. Cyclin D1 is expressed in some human malignancies and can be a potential ...  Read More

Case Reports
Malakoplakia in Association with Sigmoid Colon Adenocarcinoma,Case Report

Fatemeh Nili; Nakisa Niknejad; Mohammad Shirkhoda

Volume 14, Issue 3 , August 2019, Pages 258-260


  Malakoplakia is a rare granulomatous disease of the genitourinary system. Gastrointestinal tract is the second most common site of involvement. It usually mimics a malignancy but its association with adenocarcinoma has been rarely reported. A 59-year-old male patient with the history of weight loss ...  Read More

Case Reports Nephropathology
Biphasic Epithelial Predominant Synovial Sarcoma Presenting as Painful Thigh Mass

Elham Mirzaian; Seyed Mohammad Tavangar; Sahar Montazeri; Farbod Emami yeganeh

Volume 14, Issue 3 , August 2019, Pages 261-264


  Synovial sarcomas are soft tissue neoplasms mostly located in the lower extremities of young adults. A case of synovial sarcoma of the thigh in a 35-year-old male with the predominant epithelial component is reported. Microscopically the tumor showed variable-sized well-differentiated glands lined by ...  Read More

Case Reports Hematopathology
Mast Cell Leukemia with Ascites and Multiple Organs Damage

Elham Jafari; Ali Hadipour; Behjat Kalantari Khandani; Firoozeh Abolhasani

Volume 14, Issue 3 , August 2019, Pages 265-269


  Mast Cell Leukemia (MCL), a rare subtype of systemic mastocytosis is defined by bone marrow involvement as atypical and aleukemic mast cells, if more than 20% and less than 10% of peripheral WBCs are mast cells, respectively. We met a case of aleukemic MCL presenting with anemia and ascites for 2 years, ...  Read More

Letters to the Editor Breast Pathology
Cytoplasmic Her2/neu immunohistochemical staining in breast cancer; From a molecular point of view

Akbar Safaei; Ahmad Monabati; Maral Mokhtari; Mehdi Montazer

Volume 14, Issue 3 , August 2019, Pages 270-271


  The most widely used guideline for the breast cancer biomarker assessment and reporting (the 2013 ASCO/CAP guideline) does not state the unusual occurrence of cytoplasmic Her2/neu staining (1, 2). We recently encountered a T2N1Mx ductal adeno-carcinoma which consisted of two dissimilar tumor cell populations. ...  Read More