Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Original Research Molecular Pathology
Epidermal Growth Factor Receptor (EGFR) Gene Mutation Analysis in Adenocarcinoma of Lung, the First Report from Iran

Sahand Mohammadzadeh; Zahra Jowkar; Mitra Mirzaee; Bita Geramizadeh

Volume 14, Issue 1 , January 2019, Pages 1-7


  Background and Objective: Epidermal growth factor receptor (EGFR) gene mutation, especially in exons 18 to 21, is an important predictor of the response rate of lung adenocarcinoma to tyrosine kinase inhibitors. There are variable reports from Asian and European countries, as well as North America, about ...  Read More

Original Research
Immunohistochemical Investigation of Mutant BRAF V600E in Common Pigmented Skin Neoplasms, Study on a Sample of Iranian Patients

Maryam Ghasemi; Laleh Vahedi-larijani; Omid Emadian; Jamshid Yazdani; Ahmad Sajadianfar; Saeid Abediankenari

Volume 14, Issue 1 , January 2019, Pages 8-16


  Background & Objective: This study was designed for the first time for the detection of mutant BRAF V600E and its correlation with clinicophathologic features in a sample of Iranian patients with pathologically proved pigmented skin neoplasms.Methods: 82 paraffin-embedded blocks, including melanocytic ...  Read More

Original Research GI, Liver & Pancreas Pathology
The Correlation between Serum Zinc Level and Liver Histology in Non-Alcoholic Steatohepatitis

Farid Kosari; Raika Jamali; Tayeb Ramim; Ebrahim Musavi Jahan Abad

Volume 14, Issue 1 , January 2019, Pages 17-25


  Background & Objective: The aim of this present study was to assess the relationship between serum zinc levels and liver histopathological findings in non-alcoholic steatohepatitis (NASH) patients.Methods: This case-control study was performed in consecutively selected NASH patients who had been ...  Read More

Original Research
5-Year Survival in Gastric Adenocarcinoma with Epithelial and Stromal Versican Expression

Mohammad Hossein Sanei; Omid Mirmosayyeb; Ali Chehrei; Jamshid Ansari; Elahe Saberi

Volume 14, Issue 1 , January 2019, Pages 26-32


  Background & Objective: Gastric cancer is the second most frequent cause of cancer death worldwide, despite differences in incidence around the world. The majority of gastric cancer cases concern gastric adenocarcinoma, which has a fairly high 5-year survival rate when coupled with early-stage diagnosis. ...  Read More

Original Research Molecular Pathology
Uterine Leiomyoma and Reproductive Tract Infections Detected by Polymerase Chain Reaction

Geita Saadatnia; Aboutaleb Saremi; Behrouz Salehian; Pirooz Salehian

Volume 14, Issue 1 , January 2019, Pages 33-40


  Background and Objective: For nearly a century, it has been suspected that reproductive tract infections play an etiologic role in uterine leiomyoma. However, no epidemiologic study of leiomyoma has used the polymerase chain reaction (PCR) to compare uterine tissues from cases and non-cases, and to investigate ...  Read More

Original Research Biology & Genetic
Cell-bound Exopolysaccharide Extract from Indigenous Probiotic Bacteria Induce Apoptosis in HT–29 cell-line

Parisa Mojibi; Farzaneh Tafvizi; Maryam Bikhof Torbati

Volume 14, Issue 1 , January 2019, Pages 41-51


  Background and Objective: The aim of this study was to compare the cytotoxic effects of local probiotic bacteria, including Lactobacillus paracasei, Lactobacillus brevis, while isolated from “Tarkhine” food and the induction of apoptosis in the HT–29 human colon adenocarcinoma ...  Read More

Original Research Dermatopathology
The Study for Diagnostic Value of β-Catenin Immunohistochemistry Marker in Distinction of Aggressive and Non-Aggressive Basal Cell Carcinoma

Parvin Rajabi; Mitra Hydarpoor; Ahmadreza Maghsoudi; Fatemeh Mohaghegh; Maryam Dehghani Mobarakeh

Volume 14, Issue 1 , January 2019, Pages 52-60


  Background & Objective: Basal cell carcinoma (BCC) is a common skin cancer arising from the basal layer of the epidermis and its appendages. They are locally invasive, aggressive, and destructive of skin and the surrounding structures. β-Catenin is a multifunctional protein located to the ...  Read More

Original Research Microbiology
Bacteria Producing Extended Spectrum β-lactamases (ESBLs) in Hospitalized Patients: Prevalence, Antimicrobial Resistance Pattern and its Main Determinants

Mehdi Yousefipour; Mehrnaz Rasoulinejad; Azar Hadadi; Negin Esmaeilpour; Alireza Abdollahi; Siroos Jafari; Atieh khorsand

Volume 14, Issue 1 , January 2019, Pages 61-67


  Background and Objective: There is a growing concern regarding the lack of new antibiotics, especially for multidrug-resistant bacteria that produce Extended Spectrum β-Lactamases (ESBLs). The present study aims to assess the prevalence of bacteria producing ESBLs, their antimicrobial resistance ...  Read More

Original Research
Prevalence of Toxoplasma gondii Antibodies and DNA in Iranian HIV Patients

Anahita Bavand; Arezoo Aghakhani; Minoo Mohraz; Mohammad Banifazl; Afsaneh Karami; Majid Golkar; Jalal Babaie; Parviz Saleh; Setareh Mamishi; Amitis Ramezani

Volume 14, Issue 1 , January 2019, Pages 68-75


  Background & Objective: Toxoplasma gondii infection has public health importance and can lead to serious diseases in immunosuppressed patients, such as HIV cases. Appropriate control of T. gondii infection in HIV patients requires information about the prevalence of T. gondii antibodies and DNA in ...  Read More

Short Communication
Nodular Fasciitis – Fine Needle Aspiration Cytology Diagnosis and Its Pitfalls, with Review of Literature

Padmapriya Jaiprakash; Balaji Radhakrishnan; Ranjini Kudva; Manna Valiathan; Seetharam Prasad

Volume 14, Issue 1 , January 2019, Pages 76-82


  Background and Objective: Nodular fasciitis (NF) is a self-limiting, transient neoplasm composed of fibroblasts and myofibroblasts. Since it regresses spontaneously, diagnosis by fine needle aspiration (FNA) cytology plays a major role in its management. Methods: We present a series of 8 cases with either ...  Read More

Case Reports Endocrine Pathology
Oncocytic Variant Of Medullary Thyroid Carcinoma - A Case Report

Srilatha P.S.; Jayitri Das; Vidya Monappa

Volume 14, Issue 1 , January 2019, Pages 83-86


  Medullary thyroid carcinoma (MTC) is a rare tumor arising from parafollicular C-cells. The oncocytic variant of MTC is an extremely rare diagnosis, with less than 20 cases reported. Here we present the case of a 36-year-old male patient with complaints of neck swelling and dysphagia. On fine needle aspiration ...  Read More

Case Reports Nephropathology
Dyspnea as the First Manifestation of Silent Renal Cell Carcinoma

Atieh Khorsand-Rahimzadeh; Fatemeh Khatami; Salma Sefidbakht; Hiva Saffar; Seyed Mohammad Tavangar

Volume 14, Issue 1 , January 2019, Pages 87-93


  Renal cell carcinoma (RCC) accounts for only 3% of adult malignancies, and the lung is the most common site of metastasis of this tumor, which may be accompanied by pleural metastasis. However, solitary pleural involvement is very rare and its presentation with dyspnea as the first manifestation of RCC ...  Read More

Letters to the Editor GI, Liver & Pancreas Pathology
False Negative Fecal Occult Blood Test: Prozone Effect

Pathoom Sukkaromdee; Viroj Wiwanitkit

Volume 14, Issue 1 , January 2019, Pages 94-94


  Dear editor, the fecal occult blood test is the presently widely used screening laboratory test for colorectal cancer. At present, the test is usually based on an immunological diagnostic principle (1, 2). A false positive fecal occult blood is common and widely mentioned in literature. Nevertheless, ...  Read More