TY - JOUR ID - 8315 TI - Endobronchial Metastasis of Pheochromocytoma 25 Years after Primary Tumor JO - Iranian Journal of Pathology JA - IJP LA - en SN - 1735-5303 AU - Kadivar, Maryam AU - Babaheidarian, Pegah AU - Zare Mirzae, Ali AU - Fakhraie, Mohammadreza AD - Dept. of Pathology, Tehran University of Medical Sciences, Tehran, Iran AD - Surgery Ward, Atieh Hospital, Tehran, Iran Y1 - 2013 PY - 2013 VL - 8 IS - 2 SP - 115 EP - 118 KW - Pheochromocytoma KW - Lung KW - Metastasis DO - N2 - There are few reported cases of endobronchial metastasis of pheochromocytoma literature. We present here a 56-year old woman who underwent left lower lobectomy of lung, following pneumonia with unresolved chest radiographs. Computed tomography showed a lobulated soft tissue mass, measuring, 38×27 mm, at the perivascular space of anterior mediastinum. The resected specimen, showed lobulated tumor arranged in nesting pattern within arcuate vascular network. Immunohistochemistry showed intense positive staining of epitheloid cell (chief cells) for chromogranin and synaptophysin which were negative for cytokeratin. Sustentacular cells were strongly positive for S-100. Although very rare, physicians should keep in mind the possibility of endobronchial metastasis in patients with a history of pheochromocytoma.   UR - https://ijp.iranpath.org/article_8315.html L1 - https://ijp.iranpath.org/article_8315_b18b41cfcc56c7ac2654f827b95d5c89.pdf ER -