TY - JOUR ID - 25840 TI - Nosocomial Jejunal Mucormycosis - an Unusual Cause of Perforation Peritonitis JO - Iranian Journal of Pathology JA - IJP LA - en SN - 1735-5303 AU - Kumar, Chandan AU - Jain, Pragya AU - Wadhwa, Neelam AU - Diwaker, Preeti AU - Khan, Nirupma AD - Dept. of Pathology, University College of Medical Sciences, University of Delhi, Delhi, India AD - Dept. of Pathology, Guru Teg Bahadur Hospital, Shahdra, Delhi, India Y1 - 2017 PY - 2017 VL - 12 IS - 3 SP - 295 EP - 300 KW - Mucormycosis KW - nosocomial infection KW - Jejunum KW - Small Bowel DO - 10.30699/ijp.2017.25840 N2 - Mucormycosis is a rare but highly invasive opportunistic fungal infection. Gastrointestinal disease although uncommon is highly fatal. We report a case of jejunal mucormycosis in a 24 year old undernourished female with preceding surgical intervention for acute intestinal obstruction of tubercular etiology. On 8th post-operative day, she developed oozing from suture line, prompting exploratory laparotomy, bowel resection, jejunostomy and ileal mucus fistula. Resected bowel showed one perforation and several areas of impending perforations. Characteristic broad, pauci-septate hyaline, empty looking hyphae with infrequent branching were found transmurally and showing angio-invasion. Local intestinal tissue trauma coupled with her sub-normal immune status permitted this unusual nosocomial infection. Histopathologic demonstration of the fungus in surgical specimens remains cornerstone of diagnosis of mucormycosis in view of its non-specific symptoms, low isolation rates of mycologic culture and lack of other rapid tests.  UR - https://ijp.iranpath.org/article_25840.html L1 - https://ijp.iranpath.org/article_25840_947fc9a2e4886e2a64642cb879aeba3c.pdf ER -