TY - JOUR ID - 254069 TI - Evaluation of the Relationship Between Serum and Urine Ferritin Level of Low Birth Weight Infants JO - Iranian Journal of Pathology JA - IJP LA - en SN - 1735-5303 AU - Bazmamoun, Hassan AU - Narimani, Soheila AU - Shokohi, Maryam AU - Esfahani, Hossein AU - Soltanian, Ali Reza AU - Rastgoo Haghi, Alireza AD - Department of Pediatric Gastroenterology, Hamadan University of Medical Sciences, Hamadan, Iran AD - Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran AD - Department of Neonatal-Perinatal Medicine, Hamadan University of Medical Science, Hamadan, Iran AD - Department of Pediatric Hematology/Oncology, Hamadan University of Medical Science, Hamadan, Iran AD - Department of Biostatistics, Hamadan University of Medical Sciences, Hamadan, Iran AD - Department of Pathology, Hamadan University of Medical Science, Hamadan, Iran Y1 - 2022 PY - 2022 VL - 17 IS - 3 SP - 323 EP - 327 KW - Low birth weight infants KW - Serum ferritin KW - Urine ferritin DO - 10.30699/ijp.2022.546540.2807 N2 - Background & Objective: Iron deficiency before birth or in infancy can cause long-term behavioral and neurological disorders. Measuring serum ferritin is an effective way to diagnose iron deficiency but requires significant blood volume from a low birth weight infant. Therefore, the present study was performed to investigate the relationship between serum and urinary ferritin levels in low birth weight infants.Methods: In this cross-sectional study, 76 infants weighing less than 2500 g were studied. To measure serum ferritin level, 1.5 mL of blood and to measure urinary ferritin level, at least 1 mL of urine was collected from each infant. Then the results were compared. Data analysis was performed using SPSS software version 16, and the significance level was considered less than 0.05.Results: Out of 76 neonates studied, 51.3% were boys, and 80.3% were premature infants. The mean birth weight of infants was 2056.31±318.74 g, and the mean serum and urinary ferritin levels were 134.77±72.35 and 85.55±70.97 ng, respectively. There was a statistically significant relationship between serum and urinary ferritin levels. Also, serum ferritin and urinary ferritin levels had a statistically significant relationship with birth weight and gestational age. The higher the birth weight as well as the age at birth, the higher the serum ferritin and urinary ferritin.Conclusion: According to the findings of this study, measurement of urinary ferritin level can be used as a noninvasive tool for iron deficiency screening in low birth weight infants instead of serum ferritin level. UR - https://ijp.iranpath.org/article_254069.html L1 - https://ijp.iranpath.org/article_254069_56e9a3dd886000a40b96ce95806b321f.pdf ER -