%0 Journal Article %T Acinic Cell Carcinoma of the Parotid Gland with Four Morphological Features %J Iranian Journal of Pathology %I Farname Inc in collaboration with Iranian Society of Pathology %Z 1735-5303 %A Rosero, David %A Alvarez, Ramiro %A Gambó, Paula %A Alastuey, María %A Valero, Alberto %A Torrecilla, Nerea %A Roche, A. Belén %A Simón, Sara %D 2016 %\ 04/01/2016 %V 11 %N 2 %P 181-185 %! Acinic Cell Carcinoma of the Parotid Gland with Four Morphological Features %K Acinic cell carcinoma %K Morphologic patterns %K Salivary Gland %R %X Acinic cell carcinoma arising in salivary glands is a rare tumor, accounting for 2% to 5% of the primary neoplasms of the parotid gland. When these tumors are well-differentiated, the neoplasia has innocuous aspect, due to the similarity to normal parotid tissue. This makes the diagnosis difficult. Initially the malignancy of this tumor was uncertain; however, recent studies have declared it as malignant. The female / male ratio is 3:2. The nodule usually presents as solitary and well defined shape. Several authors have used different terms to describe histomorphological patterns of these tumors. Four descriptive categories (solid, microcystic, papillary-cystic and follicular) are useful for pathologists. Here we report a case of a 49 yr old man with a left parotid nodule of 5 cm. Parotidectomy was performed at the Hospital Universitario Miguel Servet, in Zaragoza (Spain). The microscopy showed a tumor with acinic semblance, having the four morphologic patterns previously described. The morphological and immunohistochemical study was consistent with the diagnosis of acinic cell carcinoma. %U https://ijp.iranpath.org/article_19283_eaf8ed7939f2a94de644558cfb57cd3a.pdf