@article { author = {Roy, Shravasti and Das, Indranil and Nandi, Ayandip and De, Soma}, title = {Retroperitoneal Anaplastic Neuroblastoma in a 3-Year-Old Female: A Rare Case Report}, journal = {Iranian Journal of Pathology}, volume = {10}, number = {3}, pages = {227-230}, year = {2015}, publisher = {Farname Inc in collaboration with Iranian Society of Pathology}, issn = {1735-5303}, eissn = {2345-3656}, doi = {10.7508/ijp.2015.03.008}, abstract = {Neuroblastoma is the most common extracranial solid tumor in childhood. In different classification of neuroblastomas, a subset of undifferentiated or poorly differentiated tumors with bizarre histological features has been mentioned. A 3-year-old girl presented with abdominal pain. Her haematological and biochemical parameters were normal except her urinary vanelylmandelic acid level was elevated five times the normal value (64.4 IU/ml). On computed tomographyscan, a retroperitoneal contrast-enhancing mass was visible around D12-D13 region (60×52×47mm). Sections of CT guided trucut biopsy revealed large cells with pleomorphic nuclei, abundant cytoplasm and occasional multinucleated giant cells. Immunohistochemistry showed the cells reactive for neuron specific enolase, chromogranin-A, synaptophysin, non-reactive for cytokeratin, desmin and glial fibrillary acid protein and Alk-1. A diagnosis of anaplastic neuroblastoma was made. The child is currently under chemotherapy and doing well.   How to cite this article: Roy S, Das I, Nandi A, De S. Retroperitoneal Anaplastic Neuroblastoma in a 3-Year-Old Female: A Rare Case Report. Iran J Pathol. 2015;10(3):227-30.}, keywords = {Neuroblastoma,Retroperitoneal Space, Case Report}, url = {https://ijp.iranpath.org/article_11614.html}, eprint = {https://ijp.iranpath.org/article_11614_8b567093bbb7d39a05683a9e96b31f0c.pdf} }