Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Breast Pathology
Revisiting Metaplastic Carcinoma of Breast: An Emphasis on the Clinico-pathological and Immunohistochemical Variables Analyzed at a Tertiary Cancer Centre in South India

Geetha V Patil Okaly1; Akshatha C; Sandhya N; Akina Prakash; M N Suma; Ashwini Nargund; Shankar Anand; C Ramachandra; Libin Babu Cherian

Articles in Press, Corrected Proof, Available Online from 12 August 2022

http://dx.doi.org/10.30699/ijp.2022.541798.2757

Abstract
  Background & Objective: Metaplastic carcinoma is a diverse variant of invasive breast carcinomas (IBC) characterized by dedifferentiation of malignant cells towards squamous and/or mesenchymal elements. It accounts for 0.3-1.2% of all IBC. These tumors are typically triple-negative by hormonal profiling ...  Read More

Breast Pathology
Crosstalk Between Programmed Death Ligand 1, Ki-67 Labelling Index, and Tumor-Infiltrating Lymphocytes in Invasive Breast Cancer and Clinicopathological Correlations in a Tertiary Care Center in Western India

Rashim Sharma; Poonam Abhay Elhence; Meenakshi Rao; Sudeep Khera; Deepak Vedant; Ramkaran Chaudhary; Puneet Pareek; Jeewan Ram Vishnoi; Sanjeev Misra

Articles in Press, Corrected Proof, Available Online from 13 August 2022

http://dx.doi.org/10.30699/ijp.2022.539946.2737

Abstract
  Background & Objective: Breast cancer is the leading cancer among Indian women and accounts for about 25% of all cancer cases worldwide. The present study aimed to assess Programmed Death Ligand-1 (PD-L1) expression in tumoral cells and tumor-infiltrating lymphocytes (TILs) and evaluate their correlations ...  Read More

Breast Pathology
Apoptosis Induction, Cell Cycle Arrest and Anti-Cancer Potential of Tamoxifen-Curcumin Loaded Niosomes Against MCF-7 Cancer Cells

Mahdi Fatemizadeh; Farzaneh Tafvizi; Farzaneh Shamsi; Sahar Amiri; Afsaneh Farajzadeh; Iman Akbarzadeh

Volume 17, Issue 2 , April 2022, , Pages 183-190

http://dx.doi.org/10.30699/ijp.2022.124340.2358

Abstract
  Background & Objective: Breast cancer is the most common cancer among women. One of the most effective treatments for breast cancer is chemotherapy, in which specific drugs destroy the mass and its proliferation is inhibited. Chemotherapy is the most effective adjunctive therapy when multiple medications ...  Read More

Breast Pathology
A Novel Subset of Triple-Negative Breast Cancers with Unique Histology and Immunohistochemical Expression

Swaminathan Kalyanasundaram; Shantaraman Kalyanaraman; Hidhaya Kaleelullah Fathima; Vidhya Mohan; Kavitha Selvaraj

Volume 17, Issue 2 , April 2022, , Pages 217-224

http://dx.doi.org/10.30699/ijp.2022.139734.2526

Abstract
  Background & Objective: Triple-Negative Breast Carcinoma (TNBC) is characterized by an absence of estrogen receptor, progesterone receptor and HER2 neu expression, with distinct molecular, histological and clinical features, aggressive clinical course and a poor prognosis. The objective was to evaluate ...  Read More

Breast Pathology
MiRNA-218 Is Frequently Downregulated in Malignant Breast Tumors: A Footprint of Epstein-Barr Virus Infection

Javad Charostad; Mohsen Nakhaie; Azarakhsh Azaran; Gholam Abbas Kaydani; Akram Astani; Azim Motamedfar; Manoochehr Makvandi

Volume 16, Issue 4 , August 2021, , Pages 376-385

http://dx.doi.org/10.30699/ijp.2021.521107.2550

Abstract
  Background & Objective: The role of Epstein-Barr Virus in development of breast cancer is frequently studied. In this regard, miRNAs are among the contributing elements in the molecular pathophysiology of EBV-related diseases. In addition, a growing number of host miRNAs are believed to be implicated ...  Read More

Breast Pathology
Role of Cell Block Technology as an Adjunct to Fine Needle Aspiration in Evaluating as well as Differentiating Liver Lesions

Sujata Mallick; Mahasweta Mallik; Rabindra Nath Chatterjee; Puskar Shyam Chowdhury

Volume 16, Issue 4 , August 2021, , Pages 392-402

http://dx.doi.org/10.30699/ijp.2021.522897.2569

Abstract
  Background & Objective: Liver lesions are difficult to diagnose and to differentiate primary from metastatic carcinoma, while Biopsy has its limitations. Cell block technology is easily accessible with high diagnostic accuracy. Our aim is 1) To find the role of cell block technology as an alternative ...  Read More

Breast Pathology
Myofibroblastoma of the Breast: A Morphologic and Immunohistochemical Study of Three Cases

Hiva Saffar; Dorna Motevalli; Nasibeh Seirfar; Mahsa Ebrahimi; Perikala Vijayananda Kumar; Farid Kosari; Hedieh Moradi Tabriz; Sadaf Naderi; Golsa Shekarkhar

Volume 16, Issue 4 , August 2021, , Pages 451-455

http://dx.doi.org/10.30699/ijp.2021.138647.2520

Abstract
  Myofibroblastoma (MFB) of the breast is an uncommon entity of benign spindle neoplasms of the breast. This tumour possesses a broad spectrum of histomorphological patterns. Distinguishing of myofibroblastoma variants from malignant mimics of this benign neoplasm is essential for pathologists to avoid ...  Read More

Breast Pathology
HE4, A New Potential Tumor Marker for Early Diagnosis and Predicting of Breast Cancer Progression

Nazanin Mirmohseni Namini; Alireza Abdollahi; Monireh Movahedi; Amirnader Emami Razavi; Reza Saghiri

Volume 16, Issue 3 , July 2021, , Pages 284-296

http://dx.doi.org/10.30699/ijp.2021.135323.2482

Abstract
  Background & Objective: This study examined the potential of human epididymis protein 4 (HE4) as a marker in early diagnosis or as a prognostic factor for breast cancer (BC) patients.Methods: A total of 31 patients diagnosed with BC were enrolled in the study between 2008 and 2018. The mRNA and protein ...  Read More

Breast Pathology
D2-40 A Helpful Marker in Assessment of Lymphatic Vessel Invasion in Carcinoma of BreastTumor characteristic Number of cases (percentage %)

Zeinab Vosough; Shima Golbini; Majid Sharbatdaran; Akramossadat Hosseini

Volume 16, Issue 2 , April 2021, , Pages 96-102

http://dx.doi.org/10.30699/ijp.2020.114511.2245

Abstract
  Background & Objective: Breast cancer is the most common malignancy in Iranian women and worldwide. Lymphatic vessel invasion (LVI) was found to be an independent prognostic factor in many carcinomas, including invasive carcinoma of the breast. The aim of this study was to compare the hematoxylin ...  Read More

Breast Pathology
Evaluation of the Relationship Between Expression of Villin and Gelsolin Genes and Axillary Lymph Node Metastasis in Patients with Breast Cancer

Armin Borhan; Zohreh Nozarian; Alireza Abdollahi; Reza Shahsiah; Hadiseh Mohammadpour; Arash Borhan

Volume 16, Issue 1 , January 2021, , Pages 27-32

http://dx.doi.org/10.30699/ijp.2020.121532.2322

Abstract
  Background & Objective: Nowadays, actin-binding proteins such as Villin and Gelsolin have been considered to be associated with aggressive tumors. This study mainly aims to determine the relationship between Gelsolin and Villin genes expression and metastasis of axillary lymph nodes in patients with ...  Read More

Breast Pathology
Androgen Receptor Expression and Its Correlation with Clinicopathological Parameters in Iranian Patients with Triple Negative Breast Cancer

Azar Naimi; Maryam Sultan; Elham Amjadi; Parvin Goli; Amirhosein Kefayat

Volume 15, Issue 3 , July 2020, , Pages 239-244

http://dx.doi.org/10.30699/ijp.2020.112819.2224

Abstract
  Background & Objective: Our knowledge about correlation of androgen receptor expression and clinicopathological properties of triple-negative breast cancer (TNBC) patients is inadequate, particularly in the Iranian population. The main aim of the present study was to assess the AR expression in TNBC ...  Read More

Breast Pathology
Changes in Cytokeratin 18 during Neoadjuvant Chemotherapy of Breast Cancer: A Prospective Study

Danial Fazilat-Panah; Somaye Vakili Ahrari Roudi; Alireza Keramati; Azar Fanipakdel; Mohammad hadi Sadeghian; Fatemeh Homaei Shandiz; Soudabeh ShahidSales; Seyed Alireza Javadinia

Volume 15, Issue 2 , April 2020, , Pages 117-126

http://dx.doi.org/10.30699/ijp.2020.116238.2261

Abstract
  Background & Objective: Prediction of response to neoadjuvant treatment is an important part of treatment of patients with breast cancer. This study aimed to assess changes in serum levels of Cytokeratin 18 during neoadjuvant chemotherapy in patients with locally advanced breast cancer and its association ...  Read More

Breast Pathology
Assessment of Ki67 in Breast Cancer: A Comparison Between the Eye-10 Method, Stepwise Counting Strategy, and International System of Ki67 Evaluation

Maryam Kadivar; Fatemeh Aram

Volume 15, Issue 1 , January 2020, , Pages 13-18

http://dx.doi.org/10.30699/ijp.2019.102290.2017

Abstract
  Background & Objective:Ki-67 evaluation is an essential tool to define luminal A and B breast cancers, which is not yet systematized. The International Ki67 in Breast Cancer Working Group suggests the counting of 500 or 1000 cancer cells, which is a time-consuming process. Therefore, novel methods, ...  Read More

Breast Pathology
The Difference of Expression of 18 Genes in Axillary Invasion and Vascular Invasion Compared to Control Samples in Breast Cancer

Alireza Abdollahi; Sepideh Jahanian; Nima Hemmati; Hadiseh Mohammadpour

Volume 14, Issue 3 , August 2019, , Pages 223-231

http://dx.doi.org/10.30699/ijp.2019.92094.1894

Abstract
  Background & Objective: Recent studies from gene profiling have revealed some genes that are overexpressed in the epithelial-mesenchymal transition (EMT) process and are responsible for its initiation and activation resulting in tumor progression and metastasis. The present study aimed to assess ...  Read More

Breast Pathology
Vascular Mimicry Expression in Invasive Ductal Carcinoma; A New Technique for Prospect of Aggressiveness

Amir Hosein Jafarian; Melika Kooshkiforooshani; Abdolshakor Rasoliostadi; Nema Mohamadian Roshan

Volume 14, Issue 3 , August 2019, , Pages 232-235

http://dx.doi.org/10.30699/ijp.2019.94997.1939

Abstract
  Background & Objective: In vascular (vasculogenic) mimicry (VM), tumoral cells mimic the endothelial cells and form the extracellular matrix-rich tubular networks. It has been proposed that VM is more extensive in aggressive tumors. This study was designed to investigate the rate of VM expression ...  Read More

Breast Pathology
Cytoplasmic Her2/neu immunohistochemical staining in breast cancer; From a molecular point of view

Akbar Safaei; Ahmad Monabati; Maral Mokhtari; Mehdi Montazer

Volume 14, Issue 3 , August 2019, , Pages 270-271

http://dx.doi.org/10.30699/ijp.2019.76630.1732

Abstract
  The most widely used guideline for the breast cancer biomarker assessment and reporting (the 2013 ASCO/CAP guideline) does not state the unusual occurrence of cytoplasmic Her2/neu staining (1, 2). We recently encountered a T2N1Mx ductal adeno-carcinoma which consisted of two dissimilar tumor cell populations. ...  Read More