Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Serous Borderline Ovarian Epithelial Type Tumors of Testis in A Young Man with Only Mass Resection: A Case Report

Mandana Rahimi; Yasaman Moradi; Farhood Khaleghimehr

Volume 18, Issue 4 , October 2023, , Pages 476-479


  Tumors of the ovarian epithelial type of testis are an infrequent entity. We report a case of borderline serous tumor in an 18-year-old male who presented with a right testicular mass, clinically suspicious of carcinoma. After right inguinal exploration, two pedunculated para-testicular masses were identified ...  Read More

Diagnostic Significance of Cytokeratin 20 and p53 as Adjunct Immunocytological Markers in Urine Cytology to Detect Urothelial Carcinomas: A Systematic Review Study

Evelyn - Angel

Volume 18, Issue 3 , July 2023, , Pages 257-269


  The progression and recurrence of urothelial carcinoma (UC) are correlated with carcinoma in situ and urothelial dysplasia. It is frequently challenging to distinguish dysplasia and carcinoma in situ from reactive atypia only based on histological characteristics. In daily practices, 2 of the adjunct ...  Read More

The Prevalence of p16 Expression in Urothelial Bladder Cancer in a Tertiary Care Hospital of Chattogram, Bangladesh

Taniza Farnaz; Pradip Bhattacharjee; M. Shahab Uddin Ahamad; Sharmin Ashraf Rima; Naznin Nahar Momin; Anika Sadaf

Volume 18, Issue 3 , July 2023, , Pages 306-311


  Background & Objective: p16 is a tumor suppressor gene, loss of which is usually associated with poor epithelial differentiation, resulting in tumor progression, which correlates with aggressive clinical behavior and poor prognosis. CDK 4/6 inhibitors can be used as a therapeutic target in p16 negative ...  Read More

Evaluation of Cytokeratin-7 and Cytokeratin-19 Expression Relationship with Gleason Score in Prostatic Adenocarcinoma

Masood Soltanipur; Mohammadreza Jalali Nadoushan; Hossein Yarmohammadi

Volume 18, Issue 3 , July 2023, , Pages 363-369


  Background & Objective: Prostatic adenocarcinoma (PAC) is one of the most common tumors worldwide. Immunohistochemical expression of cytokeratins has been evaluated in the diagnosis and prognosis of tumors. The aim of the present study is the evaluation of Cytokeratin-7 (Ck-7) and Cytokeratin-19 ...  Read More

Protein Expression of NEK2, JMJD4, and REST in Clear Cell Renal Cell Carcinoma (ccRCC): Clinical, Pathological, and Prognostic Findings

Walid S. H. Elsayed; Ola Harb; Mohamed A Alabiad; Rema H. Faraj Saad; Amal Anbaig; Mohamed Alorinin; Rehab Hemeda; Mohamed Negm; Loay M Gertallah; Walled A Abdelhady; Ramadan M Ali

Volume 18, Issue 2 , April 2023, , Pages 180-192


  Background & Objective: Cells of renal cell carcinoma (RCC) are resistant to the most currently used chemotherapeutic agents and targeted therapies; hence, we evaluated the expression of NEK2, JMJD4, and REST in tissues of clear cell renal cell carcinoma (ccRCC) and benign nearby tissues of kidney ...  Read More

Accuracy of Paris 2016 System for Non-invasive Diagnosis Bladder Malignancy

Azadeh Rakhshan; Esmat Arvin; Sam Alahyari; Behrang Kazeminezhad; Tahmineh Mollasharifi; Alireza Bagheri; Fereshte Aliakbari; Seyed Jalil Hosseini; Mohammad Soleimani; Mahsa Ahadi; Elena Jamali; Afshin Moradi; Zahra Sadeghzadeh; Saleh Ghiasi; Malihe Nasiri; Farzad Allameh

Volume 17, Issue 3 , July 2022, , Pages 328-334


  Background & Objective: The Paris System for Reporting Urinary Cytology (TPS) is a new method for evaluating urinary cytology designed to reduce unreproducible reports. The aim of this study was to reclassify and compare urinary cytology reports with TPS criteria to determine the frequency of unreproducible ...  Read More

Diagnostic and Therapeutic Implications of Sortilin Expressed on the Surface of Bladder Carcinoma Cells

Ali-Ahmad Bayat; Niloufar Sadeghi; Ghazaleh Fazli; Mohammad Reza Nowroozi; Solmaz Ohadian Moghadam; Amin Radmanesh; Mohammadjavad Hedayatshodeh; Ali Reza Sarrafzadeh; Omid Zarei; Fatemeh Ghaemimanesh; Hodjattallah Rabbani

Volume 17, Issue 2 , April 2022, , Pages 174-182


  Background & Objective: Cell surface expression of sortilin in different types of cancer signifies it as a therapeutic target for cancer therapy. The aim of this study was to detect sortilin expression in bladder cancer cells using an anti-sortilin monoclonal antibody (mAb) to evaluate sortilin as ...  Read More

Direct Smear Versus Liquid-Based Cytology in the Diagnosis of Bladder Lesions

Mahmoud Reza Kalantari; Mohammad Ali Jahanshahi; Masoumeh Gharib; Sara Hashemi; Shakiba Kalantari

Volume 17, Issue 1 , January 2022, , Pages 56-64


  Background & Objective: Urine cytology is an important diagnostic method for urinary tract cancers (especially carcinomas), which is suitable for follow-up of residual urothelial tumors after surgery of malignant bladder tumors. In this study, for the first time, liquid-based cytology (LBC) was used ...  Read More

The Expression of Autophagy Markers Beclin1 and LC3B in Prostatic Carcinoma: Immunohistochemical Case-Control Study

Nanis Shawky Holah; Marwa Mohammed Serag El-Dien; Shereen Fathy Mahmoud

Volume 17, Issue 1 , January 2022, , Pages 75-84


  Background and Objective: Prostatic carcinoma represents the second most common cancer diagnosed in men worldwide after lung cancer and the fourth common male malignancy in Egypt. Autophagy is a natural process that has both oncogenic and tumor-suppressive activities. This study aims to evaluate the ...  Read More

Significance of Vascular Endothelial Growth Factor Expression in the Bladder Urothelial Carcinoma and Its Association with Tumor Grade and Invasiveness

Anika Sadaf; Zillur Rahman; Pradip Bhattacharjee; M. Shahab Uddin Ahamad; Sayeeda Nasreen

Volume 16, Issue 4 , August 2021, , Pages 362-369


  Background & Objective: Vascular Endothelial Growth Factor (VEGF) is one of the newer molecular markers that acts as a central mediator of tumor angiogenesis and is essential for tumor growth, progression, and metastasis. So anti-angiogenic drugs can be used as anticancer therapy. Treatments with ...  Read More

Evaluation of ERG Expression in Prostate Adenocarcinoma and Its Prognostic Impact in Patients Survival Rate

Hedieh Moradi Tabriz; Leila Aghapour Sabaghi; Amirreza Nabighadim; Elham Nazar; Seyed Mohammad Kazem Aghamir

Volume 16, Issue 4 , August 2021, , Pages 411-417


  Background & Objective: Some certain markers, including prostatic specific antigen (PSA), are being used to screen prostate cancer (PC), but none of them have sufficient sensitivity and specificity for evaluation of prognosis. Currently, genetic variants have found their place in the prognosis of ...  Read More

Primary Testis Leiomyosarcoma: A Case Report

Elham Nazar; Zohre Shabanzadeh; Amir Ahmadi; Niloofar Rostami

Volume 16, Issue 4 , August 2021, , Pages 461-464


  Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develop  after radiotherapy or long term taking anabolic steroid medication . We report a  53-year-old male patient with primary testis leiomyosarcoma  who presented with painless testicular  enlargement ...  Read More

Evaluation of P53 and CK20 Immunohistochemical Markers in Comparison with Morphologic Findings in Low- and High-grade Urothelial Carcinomas

Mahsa Ahadi; Afshin Moradi; Banafshe Bayat; Hanieh Zham; Seyed Jalil Hosseini; Sara Zahedifar; Afsoon Taghavi

Volume 16, Issue 3 , July 2021, , Pages 297-303


  Background & Objective: Urothelial carcinoma is the seventh most common cancer in the world. The histological classification of papillary carcinoma is one of the most important determinants for its prognosis. Sometimes there is an overlap in the extent of the tumor, and the accurate microscopic diagnosis ...  Read More

Expression of PAX2 and PAX8 in Wilms Tumor: A Tissue Microarray-based Immunohistochemical Study

Salma Sefidbakht; Atieh Khorsand-Rahimzadeh; Sahar Omidi; Sedigheh Mohsenpourian; Elham Mirzaian

Volume 16, Issue 3 , July 2021, , Pages 310-315


  Background & Objective: There is currently inadequate information about the expression of immunohistochemical markers in pediatric tumors. Paired box genes 2 and 8 (PAX2 and PAX8) genes have an essential role in kidney organogenesis. This study aimed to investigate the IHC expression of PAX2 and ...  Read More

Survey of Mast Cell Density in Transitional Cell Carcinoma

Hedieh Moradi Tabriz; Maedeh Obohat; Farzan Vahedifard; Arezoo Eftekharjavadi

Volume 16, Issue 2 , April 2021, , Pages 119-127


  Background & Objective: Transitional cell carcinoma (TCC) is the world's seventh most common tumor and forms more than 90% of urinary bladder tumors. Invasive tumors have had a poor prognosis, even with surgical treatment and chemotherapy. Some studies have found that an increase of mast cells in ...  Read More

Survivin and Her2 Expressions in Different Grades of Urothelial Neoplasms of Urinary Bladder

Hedieh Moradi Tabriz; Elham Nazar; Seyed Ali Ahmadi; Esmaeil Azimi; Fazeleh Majidi

Volume 16, Issue 2 , April 2021, , Pages 154-161


  Background and Objective: Urothelial neoplasm (UN) of bladder is a potentially lethal malignancy, particularly in locally advanced or metastatic cases. Development of molecular markers such as HER2 and Survivin may provide useful information on diagnosis and prognosis in UN of bladder. Materials and ...  Read More

Burned-out Post Pubertal Teratoma Presenting as a Liver Metastases in a 34-Year-Old Male

Fereshteh Ameli; Pooneh Panahi; Vahid Soleimani

Volume 16, Issue 2 , April 2021, , Pages 232-236


  Germ cell teratomas belong to nonseminomatous germ cell tumors and account for 95% of malignant testicular tumors. Regarding the current World Health Organization (WHO) criteria, testicular teratomas are divided into prepubertal and postpubertal subtypes based on patients’ age. The term “burned-out ...  Read More

Five-year Survival Rate of Bladder Cancer in Iran during 2001-2007

Maryam Khayamzadeh; Fereshte Aliakbari; Zahra Zolghadr; Majid Emadeddin; Mahsa Ahadi; MohammadEsmaeil Akbari; Amir Reza Abedi; Shahrzad Nematollahi; Seyed Jalil Hosseini

Volume 16, Issue 1 , January 2021, , Pages 69-74


  Background & Objective: Bladder cancer is the fourth most common cancer in men and the most common cancer in women, comprising 8% of all males and 3% of female tumors. The present study aimed to estimate the five-year survival rates of bladder cancer in Iran.Methods: Information on3,337 registered ...  Read More

Diagnostic Value of Cytokeratin 34 beta E12 (Ck34βE12) and α-Methylacyl-CoA racemase (AMACR) Immunohistochemical Expression in Prostatic Lesions

Ikram A. Hasan; Hiba Gaidan; Methaq Al-kaabi

Volume 15, Issue 3 , July 2020, , Pages 232-238


  Background & Objective:Some prostatic lesions contain small suspicious foci for prostatic carcinoma in which the morphological features are equivocal. Two immunohistochemical markers namely, cytokeratin 34 beta E12 (Ck34βE12) and α-Methylacyl-CoA racemase (AMACR), were evaluated in these ...  Read More

Sarcomatoid Carcinoma of the Penis: An Uncommon Penile Neoplasm

Sucheta Gandhe; Rahul Patil; Raj Nagarkar

Volume 15, Issue 2 , April 2020, , Pages 151-153


  Sarcomatoid squamous cell carcinomas are extremely rare, high grade, aggressive variant of penile cancers. Sarcomatoid carcinoma are biphasic neoplasms with a combination of both sarcomatoid components and carcinomatous elements. These neoplasms are very rare in the urogenital system. We report a 53-year-old ...  Read More

Solitary Fibrous Tumor of the Prostate: A Diagnostic Challenge: A Case Report

Nilay Nishith; Monika Gupta; Nidhi Kaushik; Rajeev Sen

Volume 15, Issue 1 , January 2020, , Pages 41-44


  Solitary fibrous tumor (SFT) of prostate is an unusual type of mesenchymal neoplasm that can elicit a benign or malignant phenotype. It represents a diagnostic challenge as it can simulate poorly differentiated adenocarcinoma and various mesenchymal neoplasms of prostate. We report a case of prostate ...  Read More

Sarcomatoid Chromophobe Renal Cell Carcinoma with Heterologous Component

Sushma Bharti; Gautam Ram Choudhary; Jyotsna Naresh Bharti; Garg Pawan Kumar; Arsha BS; Poonam Abhay Elhence

Volume 15, Issue 1 , January 2020, , Pages 56-60


  Clear cellrenal cell carcinoma (RCC) is the most common malignant renal tumor in adults, while chromophobe RCC (CRCC) is the third most common. Any subtypes of RCC can undergo sarcomatoid differentiation, but heterologous differentiation in sarcomatoid area is very rare in RCC. Here a61-year male is ...  Read More

Evaluation of the Standardization in Semen Analysis Performance According to the WHO Protocols Among Laboratories in Tehran, Iran

Mahsa Ahadi; Fereshte Aliakbari; Saeedeh Latifi; Seyed Jalil Hosseini; Atossa Gharib; Abolfazl Movafagh; Zahra Abdolalian; Arash Dehghan; Arsham Moradi; Behrang Kazeminejad; Azadeh Rakhshan; Elena Jamali; Farzad Allameh; Afshin Moradi

Volume 14, Issue 2 , April 2019, , Pages 142-147


  Background and Objective: Infertility refers to the failure in achieving pregnancy of a couple after one year of regular sexual intercourse without using a protection method. The purpose of this research work was to evaluate the current status of the test and quality control performance in semen analysis ...  Read More

Lymphoepithelial – Like Carcinoma with Papillary Transitional Cell Carcinoma of the Urinary Bladder Associated with Carcinoma in situ Changes of the Urothelium; A Case Report and Review of Literature

Yahya Attaran; Simin Moghdam; Ahmad Monabati; Reza Sarkeshikian

Volume 14, Issue 2 , April 2019, , Pages 156-164


  Lymphoepithelial - like carcinoma, is rarely recognized in the urinary bladder and less commonly occurs with papillary transitional cell carcinoma i.e. mixed pattern. Also, less uncommon is the occurrence of carcinoma in situ changes in the adjacent urothelium of these tumors. Here, a case of lymphoepithelial ...  Read More

Renal Capillary Hemangioma Mimicking Urothelial Carcinoma, A Case Report and Review of the Literature

Bita Geramizadeh; Nadereh Shams; Pouya Iranpour; Mohammad javad Rajabi

Volume 14, Issue 2 , April 2019, , Pages 175-179


  Renal hemangioma is a rare tumor which can be capillary or cavernous. There have been less than 30 renal capillary hemangioma cases reported in the English literature. Herein we will report a case of renal hemangioma which was detected in a 74-year-old man operated with the impression of urothelial ...  Read More