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Gynecologic Pathology
The HER-2 as a Target Gene of Curcumin to Protect Hepatocytes Against the Arsenic-induced Carcinoma in Mice

Mahdi Ahadi; Vahid Naseh; Masoud Salehipour

Volume 12, Issue 2 , April 2017, , Pages 158-164

https://doi.org/10.30699/ijp.2017.24874

Abstract
  Background & objective: The HER-2 gene is an important on co protein overexpressed in many types of cancers. The current study hypothesized that curcumin downregulates HER-2 and inhibits the signal transduction pathway of PI3K/Akt, MAPK, and activation of NFκB, which could be useful to treat ...  Read More