Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Gynecologic Pathology
The Association Between Higher Expression of Talin-1 and the Reduced Survival Rate in Ovarian Serous Carcinoma Patients

Mina Sharbatoghli; Leili Saeednejad Zanjani; Fahimeh Fattahi; Elham Kalantari; Zohre Habibi Shams; Mahshid Panahi; Mehdi Totonchi; Mohsen Asadi-Lari; Zahra Majd

Volume 18, Issue 3 , July 2023, , Pages 312-326


  Background & Objective: Talin-1 is a constituent of the multiprotein adhesion complexes that play  main role in the formation of tumors and migration in different types of malignancies. The present study aimed to assess  expression and prognostic significance of the talin-1 protein in ovarian ...  Read More

P53 IHC Result as a Prognostic Tool in MDS

Alireza Rezvani; Ahmad Monabati; Zahra Kargar; Akbar Safaie; Mahdi Mahmoodzadeh; Hamideh Moosapour; Marzieh Hosseini; Soleiman Kheiri; Elham Taheri

Volume 18, Issue 3 , July 2023, , Pages 327-334


  Background & Objective: Some of the patients with myelodysplastic syndrome (MDS) are categorized as good prognosis based on the Revised International Prognostic Scoring System (IPSS-R). However, these patients may have poor clinical outcomes. It seems that the current diagnostic tools and IPSS-R ...  Read More

Breast Pathology
Correlation of Before and After Invasive Breast Cancer Neoadjuvant Chemotherapy for NFkB, Cyclin D1, and Survivin Expression

Primariadewi Rustamadji; Elvan Wiyarta; Ineke Anggreani

Volume 18, Issue 2 , April 2023, , Pages 156-164


  Background & Objective: Patients undergoing neoadjuvant chemotherapy (NC) for invasive breast cancer (IBC) therapy need biomarkers to track their progress. Because of the relationship between NFkB, Survivin, and Cyclin D1 with NC resistance, the different expression levels of each of these biomarkers ...  Read More

Protein Expression of NEK2, JMJD4, and REST in Clear Cell Renal Cell Carcinoma (ccRCC): Clinical, Pathological, and Prognostic Findings

Walid S. H. Elsayed; Ola Harb; Mohamed A Alabiad; Rema H. Faraj Saad; Amal Anbaig; Mohamed Alorinin; Rehab Hemeda; Mohamed Negm; Loay M Gertallah; Walled A Abdelhady; Ramadan M Ali

Volume 18, Issue 2 , April 2023, , Pages 180-192


  Background & Objective: Cells of renal cell carcinoma (RCC) are resistant to the most currently used chemotherapeutic agents and targeted therapies; hence, we evaluated the expression of NEK2, JMJD4, and REST in tissues of clear cell renal cell carcinoma (ccRCC) and benign nearby tissues of kidney ...  Read More

Evaluation of ERG Expression in Prostate Adenocarcinoma and Its Prognostic Impact in Patients Survival Rate

Hedieh Moradi Tabriz; Leila Aghapour Sabaghi; Amirreza Nabighadim; Elham Nazar; Seyed Mohammad Kazem Aghamir

Volume 16, Issue 4 , August 2021, , Pages 411-417


  Background & Objective: Some certain markers, including prostatic specific antigen (PSA), are being used to screen prostate cancer (PC), but none of them have sufficient sensitivity and specificity for evaluation of prognosis. Currently, genetic variants have found their place in the prognosis of ...  Read More

Expression and Prognostic Significance of Cancer/Testis Antigens, MAGE-E1, GAGE, and SOX-6, in Glioblastoma: An Immunohistochemistry Evaluation

Seyed Abbas Tabatabaei Yazdi; Masoomeh Safaei; Mehran Gholamin; Alireza Abdollahi; Fatemeh Nili; Mehdi Jabbari Nooghabi; Kazem Anvari; Majid Mojarrad

Volume 16, Issue 2 , April 2021, , Pages 128-136


  Background & Objectives: Glioblastoma is the most common primary malignancy of the brain, the prognosis of which is poor. Immunotherapy with cancer/testis (CT) antigens is a novel therapeutic approach for glioblastoma. This study aimed to investigate the expression rate of MAGE-E1, GAGE, and SOX-6 ...  Read More

Hypocalcemia in Covid-19: A Prognostic Marker for Severe Disease

Ahmad Raesi; Ebrahim Saedi Dezaki; Hamideh Moosapour; Farzaneh Saeidifard; Zahra Habibi; Fereidoun Rahmani; Soleiman Kheiri; Elham Taheri

Volume 16, Issue 2 , April 2021, , Pages 144-153


  Background & Objective:  Previous studies have addressed the electrolyte abnormalitiessuch as hypocalcemiain COVID-19 patients. We aimed to compare the laboratory findings especially the electrolyte levels amongCOVID-19 patients and healthy controls and evaluate their prognostic values. Materials ...  Read More

Solitary Fibrous Tumor of the Prostate: A Diagnostic Challenge: A Case Report

Nilay Nishith; Monika Gupta; Nidhi Kaushik; Rajeev Sen

Volume 15, Issue 1 , January 2020, , Pages 41-44


  Solitary fibrous tumor (SFT) of prostate is an unusual type of mesenchymal neoplasm that can elicit a benign or malignant phenotype. It represents a diagnostic challenge as it can simulate poorly differentiated adenocarcinoma and various mesenchymal neoplasms of prostate. We report a case of prostate ...  Read More

Gynecologic Pathology
Evaluation of HER2/neu Expression in High-Grade Endometrial Carcinoma and Its Clinicopathological Correlation

Soheila Sarmadi; Narges Izadi-Mood; Nazanin Mansourzadeh; Dorna Motevalli

Volume 14, Issue 4 , October 2019, , Pages 322-328


  Background & Objective: Endometrial carcinoma (EC) has been traditionally classified into two distinct categories of low-grade and high-grade. Type I (low grade) EC, which constitutes the majority of cases, is linked to estrogen-related molecular pathways. But type II (high-grade) EC accounts for ...  Read More

The Expression of FOXE-1 and STIP-1 in Papillary Thyroid Carcinoma and Their Relationship with Patient Prognosis

Enas M. Fouad; Ola A Harb; Reham Amin Salem; Ola M El farargy; Fady M Habib; Loay M Gertallah

Volume 13, Issue 2 , April 2018, , Pages 256-271


   Background and Objective: Most patients with papillary carcinoma of the thyroid gland (PTC) have favorable outcome, but since it has severe capability to invade the nearby tissues, there is a great risk of regional and distal lymph-nodes (LNs) metastases related to poor prognostic parameters, early ...  Read More

Prognostic Significance of Reduction in Ki67 Index After Neoadjuvant Chemotherapy in Patients With Breast Cancer in Kerman Between 2009 And 2014

Vahid Moazed; Elham Jafari; Behjat Kalantari khandani; Ali Nemati; seyedamir benrazavi

Volume 13, Issue 1 , January 2018, , Pages 71-77


  Background and objective:Breast cancer is the most common malignancy among women. The Neoadjuvant chemotherapy is the treatment of choice for non-operable tumors. The Ki67 is a proliferation marker that can be used to predict the therapeutic response to chemotherapy and the patients' prognosis. Methods: ...  Read More

The Relationship between Cytokeratins 7 and 20 Expression, and Prognostic Factors in Colon Adenocarcinoma: An Immunohistochemical Study

Mohammad Hossein Gheini; Noushin Jalayer Naderi

Volume 12, Issue 2 , April 2017, , Pages 94-98


  Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. ...  Read More

Endothelin-1 expression in prostate needle biopsy specimens correlated with aggressiveness of prostatic cancer

Mojgan Asgari; Elham Eftekhar; Maryam Abolhasani; Hossein Shahrokh

Volume 12, Issue 2 , April 2017, , Pages 171-176


  Background & Objective: As the prostate adenocarcinoma is one of the most common malignant tumors in males, looking for a marker to effectively predict aggressiveness and metastatic potential in an apparently localized cancer in initial needle biopsy specimens can help the clinicians to make more ...  Read More

Prognostic Value of Lymph Node Ratio in comparison to Lymph Node Metastases in Stage III Colon Cancer

Ali Zare Mirzaei; Fatemeh Abdorrazaghi; Maryam Lotfi; Behrang Kazemi Nejad; Nasrin Shayanfar

Volume 10, Issue 2 , April 2015, , Pages 127-135


  Background & Objectives: Colon cancer is currently of high incidence and mortality rate. Identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. Recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. The aim ...  Read More

Cytokeratin 20 in Transitional Cell Carcinoma of Bladder and Its Relation with Prognostic Factors

Mohammad Hossein Ghaini; Shaghayegh Sadat Esmailnejad; Ali Davati

Volume 7, Issue 3 , July 2012, , Pages 145-150

  Background and Aims: Immunohistochemical tests are one of the most important tests, which are under study to determine the prognosis of the cancers such as transitional cell carcinoma. By the time, flexible cystoscopy and urine cytology are the routine tests for following up the patients with transitional ...  Read More

Prediction of Clinical Course and Biologic Behavior of the Bone Giant Cell Tumor Using Bax and bcl-2 Markers

Reza Ataei; Alireza Khooei; Mohammad Gharedaghi

Volume 5, Issue 2 , March 2010, , Pages 53-59

    Background and Objectives: Giant cell Tumor of bone (GCT) is often regarded as a benign tumor, but its clinical course is unpredictable, has a high rate of recurrence, and even can metastases and transform to a malignant tumor. Histological features of the tumor often could not predict its future ...  Read More

The Clinical Trend and Prognosis of Patients with Brain Glioma

Younes Roohani; Mohammad Reza Hosseinzadeh; Mahmoodreza Khalatbari; Alireza Sadeghipoor; Farid Zaeri; Azimi-Khatibani , Esmail

Volume 5, Issue 2 , March 2010, , Pages 77-82

    Background and Objectives: Gliomas are the most prevalent primary brain tumors. The purpose of this retrospective cohort study was evaluation of clinical trend and prognosis of patients with brain glioma and effective factors in prognosis. Materials and Methods: Hundred and forty-five patients ...  Read More

Male Breast Carcinoma: An Immunohistochemical Study Of 50 Cases From Iran

Fatemeh Mahjoub; Farrokh Tirgari; Afshin Abdi Rad; Mahmoud Mohammadi; Nargess Tabarzan; Omid Emadian

Volume 3, Issue 2 , March 2008, , Pages 95-99

  Background and Objective: Male breast carcinoma (MBC) is an unusual form of neoplasia, representing 0.7 to 1 percent of all breast cancer cases. Usually, the carcinoma affects patients after the sixth decade. The aim of this study was to evaluate the status of estrogen and progesterone receptors (ER ...  Read More