Pediatric Pathology
Sahar Shahriarpanah; Fatemeh Haji Ebrahim Tehrani; Ali Davati; Iman Ansari
Volume 13, Issue 3 , July 2018, , Pages 357-362
Abstract
Background and Objective: Phototherapy is one of the therapy methods for jaundice caused by hyperbilirubinemia. Vitamin D and bilirubin have two distinct routes of metabolism yet part of their syntheses is common in the liver and thus they may influence each other’s synthesis. One of the consequences ...
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Background and Objective: Phototherapy is one of the therapy methods for jaundice caused by hyperbilirubinemia. Vitamin D and bilirubin have two distinct routes of metabolism yet part of their syntheses is common in the liver and thus they may influence each other’s synthesis. One of the consequences of phototherapy not previously studied in detail is hypocalcaemia and hypomagnesaemia. The current study aimed at investigating the effect of phototherapy on serum level of calcium, magnesium, and vitamin D.Methods: The current semi-experimental investigation was conducted on 50 term infants with jaundice that had phototherapy indication. Bilirubin, calcium, magnesium, and vitamin D were measured in their blood samples at admission and then 48 hours after beginning the phototherapy. Data were analyzed with SPSS version 16 using paired-samples t test. Results and Discussion: The serum calcium was 9.85 mg/dL before phototherapy and significantly decreased after it (9.51 mg/dL) (P<0.001). Also, the mean serum magnesium was 2.21 mg/dL before phototherapy and significantly decreased after it (2.06 mg/dL) (P=0.047). The mean of serum vitamin D significantly increased after phototherapy (before 17.44 mg/dL and after 21.77 mg/dL) (P<0.0001). The current study showed that phototherapy could decrease the level of calcium and magnesium and increase the level of vitamin D.
Ahmad Talebian; Zarichehr Vakili; Safar Ali Talar; Seyede Mahbobeh Kazemi; Gholam Abbas Mousavi
Volume 4, Issue 4 , September 2009, , Pages 157-160
Abstract
Background and Objectives: Febrile convulsion is one of the most common types of seizure in childhood. Its pathogenesis is unknown, so studying its cause is valuable. The purpose of this study was to determine the serum level of zinc and magnesium in children withfebrileconvulsion (F.C) ...
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Background and Objectives: Febrile convulsion is one of the most common types of seizure in childhood. Its pathogenesis is unknown, so studying its cause is valuable. The purpose of this study was to determine the serum level of zinc and magnesium in children withfebrileconvulsion (F.C) (3 months to 6 years age). Patients and Methods: In this analytical case-control study, serum level of zinc and magnesium in 60 children with F.C in Shahid Beheshty Hospital of Kashan, center of Iran, was determined. The control group was composed of febrile children with no seizure. All children in both groups were 3 months to 6 yr of age and had not any background of disorders. Serum level of zinc & magnesium was determined by biochemical methods in all groups. Finally, the data were analyzed by SPSS and t test. Results: The mean serum level of zinc and magnesium in case group, was lower than that of zinc & magnesium in control group (P<0.05). There was no relationship between sex, type and time of seizure with serum level of zinc or magnesium in children in case group. Conclusion: There was a relationship between serum level of zinc & magnesium and the presence of F.C in children. So, it is suggested to use supplements of zinc and magnesium in diet of affected children for prophylaxis of febrile seizure recurrences.
