Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Overexpression of MicroRNA-506 in Jurkat (acute T Cell Leukemia) Cell Line

Shaghayegh Rostami Yasuj; Narges Obeidi; Gholamreza Khamisipour; Zeynab Gharehdaghi; Zivar Zangeneh

Volume 15, Issue 4 , October 2020, , Pages 282-291


  Background & Objective:  Acute lymphoblastic leukemia (ALL) is a malignant disease that arises from various mutations in B or T-lymphoid progenitors. MicroRNAs (miRNAs) regulate gene expression by binding to the 3' untranslated region of protein-coding genes. Dysregulation of miRNA expression ...  Read More

Oral Pathology
Detection of Apoptosis in Leukoplakia and Oral Squamous Cell Carcinoma using Methyl Green Pyronin and Hematoxylin and Eosin

Pooja Sharma; Anjali Narwal; Mala Kamboj

Volume 15, Issue 3 , July 2020, , Pages 189-196


  Background & Objective: Cell population and turnover are controlled by a balance between cell proliferation and apoptosis. Detection of apoptosis in oral cancer contributes to its better prognosis and improved management. This study aimed to quantify apoptotic cells in leukoplakia and oral squamous ...  Read More

Molecular Pathology
Expression Pattern of Telomerase Reverse Transcriptase (hTERT) Variants and Bcl-2 in Peripheral Lymphocytes of Systemic Lupus Erythematosus Patients

Armin Attar; Mohsen Khosravi Maharlooei; Mohammad Nazarnia; Ahmad Hosseini; Zohre Bajalli; Yalda Sadat Moeini; Ahmad Monabati; Fatemeh Amirmoezi; Mansooreh Jaberipour; Mojtaba Habibagahi

Volume 15, Issue 3 , July 2020, , Pages 225-231


  Background & Objective: It is not clear whether activated lymphocytes of patients with systemic lupus erythematosus (SLE) are more proliferative or less apoptotic. We aimed to delineate potential differences between B and T cells of SLE patients compared to healthy controls regarding the telomerase ...  Read More

Expression of Apoptosis Related and Proliferative Proteins in Malignant Lympho-Proliferative Disorders

Zeeba Jairajpuri; Rekha Ghai; Sumita Saluja; Sujala Kapur; K.T Bhowmick

Volume 12, Issue 3 , July 2017, , Pages 231-240


  Background & objective: The current study aimed to perform an immunohistochemical analysis of patterns of apoptotic and cell proliferative related protein expression in different histological grades and immune phenotypes of malignant lymphomas and other lymphoproliferative disorders Methods:This ...  Read More

Immunohistochemical and Electron Microscopic Study of the Inhibitory Effects of Olive Oil Polyphenol on Dexamethasone-Induced Apoptosis

Ali Reza Khalatbary; Behrooz Mohammadnegad; Ghazaleh Goudarzi; Ali Fazlollahpour Balef

Volume 12, Issue 1 , January 2017, , Pages 45-52


  Background: There is accumulating evidence that a polyphenol present in olive oil, oleuropein, has antioxidant, anti-inflammatory and anti-apoptotic effects. This study aimed at determining the anti-apoptotic effect of Oleuropein (Ole) on dexamethasone-induced apoptosis of mouse thymocytes. Method: Mice ...  Read More

The Pro-apoptotic Effect of Allicin on Human Colon Adenocarcinoma Cell Line HT29

Alireza Azizzadeh Delshad; Mohammad Hossein Ghaini; Marjan Heshmati

Volume 9, Issue 2 , April 2014, , Pages 124-132

    Background and Objective: The management of apoptotic cell death has been considered as a putative therapeutic strategy for cancer treatment. In the present study we investigated the putative pro-apoptotic effect of allicin, the main garlic organosulfur component with repeatedly claimed chemopreventive ...  Read More

Antiapoptotic Effects of Aspirin on CA1 Pyramidal Neurons in Adult Rats

Majid Asadi-Shekaari; Hassan Eftekhar Vaghefi; Masoud Ezzat Abadi pour; Vahid Sheibani; Ali Shams Ara; Parisima Behbahani

Volume 6, Issue 4 , September 2011, , Pages 187-192

    Background and Objective: As one of the widely used drugs, aspirin (acetyl-salicylic acid, ASA) plays an important role in stroke treatment and prevention. In a previous study, we demonstrated ASA injection at 30 min after ischemia onset is neuroprotective. To determine whether the neurons protected ...  Read More

Expression of the Apoptosis Inhibitor Bcl-2 in Sputum Eosinophils in Patients with Asthma

Ghasem Azimi; Hesam Amini; Niosha Andalibi

Volume 5, Issue 1 , January 2010, , Pages 18-21

    Background and Objectives: Apoptosis of eosinophils is of significant value in assessing the airway inflammation in patients with asthma. Our purpose was to investigate the degree of expression of the Bcl-2 protein in sputum eosinophils during acute asthma exacerbation and its relationship with ...  Read More

Temporal Correlation Of Bax Expression And Axotomy-Induced Motoneuronal Apoptosis In Adult Rats: A Morphometric, Ultrastructural And Immunohistochemical Study

Alireza Azizzadeh Delshad; Marjan Heshmati; Taki Tiraihi

Volume 3, Issue 2 , March 2008, , Pages 67-74

    Background and Objective: As apoptotic cell death is extremely involved in physiological development and many pathological situations such as cancer and neurodegenerative diseases, the understanding of its molecular machinery can be useful in designing new therapeutic strategies. The present ...  Read More