Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Gynecologic Pathology
Prevalence and Pattern of GATA3 Immunohistochemical Expression in Female Genital Tract Adenocarcinomas

Elham Mirzaian; Tahereh Doustmohammadi; Mahshid Panahi; Soheila Sarmadi; Fereshteh Ameli; Fatemeh Nili

Articles in Press, Accepted Manuscript, Available Online from 15 February 2024


  Background & Objective: GATA3 immunohistochemistry has been described as a highly sensitive marker in determining carcinomas of breast and urothelial origin. In the gynecologic system, it can be used as a marker to diagnose mesonephric or mesonephric-like carcinomas and trophoblastic tumors. The ...  Read More

Head and Neck Pathology
Sclerosing Microcystic Adenocarcinoma of the Base of Tongue with Signet Ring-Like Cell Component: A Rare Case

Parisa Mokhles; Alireza Sadeghipour; Maryam Kadivar; Nasrin Shayanfar; Zahra Keshtpour Amlashi; Pegah Alizadeh Pahlavan; Ashkan Shafiei

Volume 19, Issue 1 , January 2024, , Pages 107-113


   Sclerosing microcystic adenocarcinoma (SMA) is an uncommon neoplasm of the oral cavity, with only 14 reported cases documented in the literature.We present a case of SMA in a 65-year-old woman with a history of high-grade lymphoma who developed clear cell changes in the deep muscular layer of the ...  Read More

GI, Liver & Pancreas Pathology
Clinicopathological Significance of PTEN Expression and Its Prognostic Effect in Colorectal Adenocarcinoma Patients

Zohreh Mirzapour Abbas abadi; Fatemeh Samiee Rad; Dariush Hamedi Asl; Babak Rahmani; Mahmood Soleimani Dodaran; Amir Peimani

Volume 17, Issue 2 , April 2022, , Pages 150-158


  Background & Objective: Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene located at chromosome 10. PTEN is a regulator of the PI3K/AKT signaling pathway that inhibits cell proliferation and promotes apoptosis. PTEN loss of function occurs in a spectrum  of cancers, including ...  Read More

Pulmonary Pathology
The Frequency of Epidermal Growth Factor Receptor (EGFR) Mutation in Patients with Lung Adenocarcinoma Referred to a Lung Diseases Hospital; A Cross-Sectional Study from Iran

Sotoudeh Mohammadi; Mitra Rezaei; Fatemeh Shojaeian; Mihan Pourabdollah; Leila Mohammadi Ziazi; Sharareh Seifi; Atousa Doroodinia; Babak Salimi; Adnan Khosravi; Mohammad Amin Farhangnasab

Volume 17, Issue 2 , April 2022, , Pages 159-165


  Background & Objective: Various studies showed the use  of epidermal growth factor receptors (EGFRs) gene mutations in the therapeutic plan of patients with advanced lung cancer. This study aimed to investigate the frequency and types of EGFR gene mutations among Iranian patients with lung adenocarcinoma ...  Read More

Gynecologic Pathology
Mesonephric Adenocarcinoma of Uterine Cervix; A Case Report and Review of the Literature

Fatemeh Nili; Samaneh Salarvand; Hana Saffar; Bita Kalaghchi; Reza Ghalehtaki

Volume 16, Issue 2 , April 2021, , Pages 227-231


  Mesonephric adenocarcinoma of the uterine cervix, an extremely rare tumor of the female genital tract, derives from the remnants of embryonic mesonephric ducts and its prognosis, diagnosis and treatment is rather challenging. We report a case of a 46-year-old woman with history of abnormal uterine bleeding ...  Read More

Malakoplakia in Association with Sigmoid Colon Adenocarcinoma,Case Report

Fatemeh Nili; Nakisa Niknejad; Mohammad Shirkhoda

Volume 14, Issue 3 , August 2019, , Pages 258-260


  Malakoplakia is a rare granulomatous disease of the genitourinary system. Gastrointestinal tract is the second most common site of involvement. It usually mimics a malignancy but its association with adenocarcinoma has been rarely reported. A 59-year-old male patient with the history of weight loss ...  Read More

Orbital Metastasis from Rectal Adenocarcinoma- Report of a Rare Case

Subrata Pal; Kingshuk Bose; Abhishek Sharma; Mrinal Sikder

Volume 11, Issue 5 , October 2016, , Pages 474-477

  Colorectal carcinoma is a common malignancy in India as well as in world. Inspite of its high metastasizing ability to various organs and lymph node, orbital metastasis is exceptional. Very few cases have been reported in the world literature. We report orbital metastasis in a case of moderately differentiated ...  Read More

Correlation between Gleason scores in needle biopsy and corresponding radical prostatectomy specimens. A twelve-year review.

Maliheh Khoddami; yassaman Khademi; Maryam Kazemi Aghdam; Haleh Soltanghoraee

Volume 11, Issue 2 , April 2016, , Pages 120-126

  Background: Presence of discordance between the Gleason score on needle biopsy and the score of radical prostatectomy specimen is common and universal. In this study, we determined the accuracy of Gleason grading of biopsies in predicting histological grading of radical prostatectomy specimens and the ...  Read More

Solitary Psoas Muscle Metastasis of Gastroesphageal Junction Adenocarcinoma

Payam Azadeh; Ali Yaghobi Joybari; Samaneh Sarbaz; Hosein Ali Ghiasi; Maryam Farasatinasab

Volume 11, Issue 1 , January 2016, , Pages 76-79

  Metastasis of gastroesphageal junction (GEJ) adenocarcinoma in skeletal muscle is rare and primary sites for skeletal muscle metastases are usually lung, renal and colorectal cancer. We have encountered with the first case report of solitary psoas muscle metastasis of GEJ adenocarcinoma. Here we describe ...  Read More

Comparison of 5FU-base Chemoradiation with and without Eloxatin on Pathologic Complete Response in Neoadjuvant Chemoradiation of Rectal cancer

Ali Yaghoubi; Payam Azadeh; KhosroM M Sheibani; Mohammad Foudazi; Behrouz Shafaghi; Manouchehr Davaei

Volume 6, Issue 3 , June 2011, , Pages 110-116

    Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive ...  Read More

The Relationship between Size of Adenocarcinoma of Colon and Lymph Node Involvement

Nasser Rakhshani; Roshanak Derakhshandeh; Seyed Amir Mirbagheri; Farhad Zamani; Ahad Atef Vahid; Mitra Mehrazma

Volume 6, Issue 3 , June 2011, , Pages 117-123

  Background and Objectives: Involvement of lymph nodes is an important prognostic factor in the most cancers, including colorectal cancer. In the recent years, invasion to blood and lymphatic vessels has been shown to predict involvement of lymph nodes and the number of involved nodes has been less studied ...  Read More

Primary Stromal Sarcoma of Breast with Nodal Recurrence

Ali Yaghobi; Payam Azadeh; Sh . Moghadam; Behrouz Shafaghi

Volume 5, Issue 1 , January 2010, , Pages 43-46

    Although most breast cancers are adenocarcinomas of the mammary gland, primary breast sarcomas may also arise from mammary gland mesenchymal tissue. Sarcomas represent less than 1% of primary breast neoplasms. These tumors are at high risk of recurrence and are known to have poor prognosis. Surgical ...  Read More