Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
GI, Liver & Pancreas Pathology
Evaluation of Circulating Leptin and Its Receptor (Ob-R) Tissue Expression in Colorectal Cancer, a Report From North of Iran

Masoume Mahmoudi-Nesheli; Reza Alizadeh-Navaei; Laleh Vahedi; Omolbanin Amjadi; Tarang Taghvaei; Iradj Maleki; Ramin Shekarriz; Arash Kazemi; Versa Omrani-Nava; Maryam Alizadeh-Forutan

Volume 18, Issue 3 , July 2023, , Pages 299-305


  Background & Objective: Leptin is an adipocyte-derived hormone with a critical role in energy balance. As demonstrated by previous investigations, leptin acts as a proliferative and angiogenic factor in cancer cells. However, results regarding its role in colorectal cancer are still inconclusive. ...  Read More

GI, Liver & Pancreas Pathology
Clinicopathological Significance of PTEN Expression and Its Prognostic Effect in Colorectal Adenocarcinoma Patients

Zohreh Mirzapour Abbas abadi; Fatemeh Samiee Rad; Dariush Hamedi Asl; Babak Rahmani; Mahmood Soleimani Dodaran; Amir Peimani

Volume 17, Issue 2 , April 2022, , Pages 150-158


  Background & Objective: Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene located at chromosome 10. PTEN is a regulator of the PI3K/AKT signaling pathway that inhibits cell proliferation and promotes apoptosis. PTEN loss of function occurs in a spectrum  of cancers, including ...  Read More

GI, Liver & Pancreas Pathology
Immunohistochemical Expression of Stanniocalcin 2 in Colorectal Cancer: A Retrospective Egyptian Study

Hala M. El-hanbuli; Rehab S. Galal; Mohammed F. Darweesh; Mohamed H. Elmahdi

Volume 17, Issue 1 , January 2022, , Pages 15-22


  Background & Objective: Colorectal cancer is the third most common cause of cancer death worldwide. Stanniocalcin 2 (STC2) is a glycoprotein hormone over-expressed in many human cancers where it regulates tumor progression and invasion. Evaluating its expression in colorectal cancer and its relation ...  Read More

GI, Liver & Pancreas Pathology
LncRNA SNHG6 Silencing Could Arrest Progression of High Grade Colorectal Cancers

Amin Jafari Oliayi; Shahriar dabiri; Malek Hossein Asadi

Volume 17, Issue 1 , January 2022, , Pages 29-36


  Background & Objective: Colorectal cancer (CRC), like other cancers, needs faster and more accurate identifications. A well-timed prognosis of CRC could be an important turning point in the survival of patients. Supplementary signs, such as long non-coding RNAs (lncRNAs), could be helpful for this ...  Read More

GI, Liver & Pancreas Pathology
Candidate Molecular Biomarkers for the Non- Invasive Detection of Colorectal Cancer using Gene Expression Profiling

Mohammad Shafiei; Mahdi Alemrajabi; Ali Najafi; Amirhomayoon Keihan; Masoudreza Sohrabi

Volume 16, Issue 2 , April 2021, , Pages 203-212


  Background and Objective: Colorectal Cancer (CRC) is the third most common cancer after prostate (breast in women) and lung cancer; it is also the third cause of cancer deaths reported in both men and women in 2020. Currently, the most commonly used diagnostic tools for CRC are colonoscopy, serological ...  Read More

GI, Liver & Pancreas Pathology
Clinicopathological Significance of Tumor Stem Cell Markers ALDH1 and CD133 in Colorectal Carcinoma

maryam Rezaee; Elmira Gheytanchi; Zahra Madjd; Mitra Mehrazma

Volume 16, Issue 1 , January 2021, , Pages 40-50


  Background & Objective: Colorectal cancer (CRC) is the third most common cancer worldwide with a high mortality rate. The main causes of death in patients are recurrence and metastasis which are mainly attributed to the small subpopulation of cells within tumors called cancer stem cells (CSCs). This ...  Read More

GI, Liver & Pancreas Pathology
Interobserver Agreement in Assessing Dysplasia in Colorectal Adenomatous Polyps: A Multicentric Iranian Study

Tahmineh Mollasharifi; Mahsa Ahadi; Elena Jamali; Afshin Moradi; Parisa Asghari; Saman Maroufizadeh; Behrang Kazeminezhad

Volume 15, Issue 3 , July 2020, , Pages 167-174


  Background & Objective: Most colorectal cancers (CRCs) arise from adenomatous polyps, and clinical management of this type of polyp is highly dependent on the reliability and validity of the pathological diagnosis. The aim of this study was to examine the interobserver agreement of five pathologists ...  Read More

Evaluation of Expression of EGFR, HER-2 and COX-2 in Colorectal Cancer

Behrang Kazeminegad; Abbas Mirafsharieh; Freidoon Solhjoo

Volume 7, Issue 3 , July 2012, , Pages 139-144

  Background and objective: EGFR and HER-2 are two members of ERbB/HER family of Type I Transmembrane growth factor receptors. Cox2 is an enzyme responsible for the conversion of arachidonic acid to prostaglandins, which has a major role in angiogenesis and can modelate tumor growth. The aim of this study ...  Read More

Immunohistochemical Assessment of Neuroendocrine Differentiation in Colorectal Carcinomas and Its Relation with Age, Sex, Grade Plus Stage

Nasrin Shayanfar; Shahriar Zohourian Shahzadi

Volume 4, Issue 4 , September 2009, , Pages 167-171

  Background and Objective: Neuroendocrine differentiation has not been proved to have effects in behavior of colorectal carcinomas. The aim of this study was Immunohistochemical evaluation of neuroendocrine differentiation in colorectal cancer. Patients and Methods: In this cross-sectional study, 83 ...  Read More