Alireza Abdollahi; Saeed Shoar
Volume 7, Issue 4 , September 2012, , Pages 209-214
Abstract
Background & Objective: There are many common infections and inflammations among people over the world. This demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. In the present study, we aimed to ...
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Background & Objective: There are many common infections and inflammations among people over the world. This demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. In the present study, we aimed to find any potential correlation between serum levels of GGT and CRP- Q and/or hs- CRP and WBC count as the well- known markers of inflammation in human body.
Materials and Methods: Through a cross- sectional study, serum levels of CRP-Q, hs- CRP, and GGT, in addition to WBC count were measured in 1,500 healthy people, referred to Blood Transfusion Organization from across the country. Data were analyzed after the patients were checked by physical examination for ruling out the presence of any inflammation or other illness. Serum levels of GGT, CRP- Q, hs- CRP, and WBC count were analyzed by SPSS for windows version 16.
Results: Analysis showed a positive linear correlation between CRP- Q and hs- CRP with GGT also confirmed by non- parametric tests.
Conclusion: Serum GGT may be an inflammatory index and a useful marker in approaching to inflammatory diseases.
Nader Shavandi; Reza afshar; Abolfazl Samiei; Abbas Saremi; Rahman Sheikh Hoseini
Volume 7, Issue 3 , July 2012, , Pages 165-170
Abstract
Background and Aims: Post exercise proteinuria and increased urinary Gamma-Glutamyl transferase (GGT) levels can be indicative of exercise-induced renal damage. The aim of this investigation was to study the effect of one session of intensive training on renal tubular injury markers and compare their ...
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Background and Aims: Post exercise proteinuria and increased urinary Gamma-Glutamyl transferase (GGT) levels can be indicative of exercise-induced renal damage. The aim of this investigation was to study the effect of one session of intensive training on renal tubular injury markers and compare their values to those 6 hours after training, for evaluating tubular damage after intensive training.
Materials and Methods: In this cross-sectional study with pre- and post- test design, 10 elite volunteer male athletes were selected and participated in one training session (2 hours). Urine samples were collected before training, one hour after training, and 6 hours after training. Urinary protein, creatinine, and GGT values were measured through laboratory methods and then Pr/Cr and GGT/Cr ratios were computed.
Results: There weresignificant differences between values of protein, urine Pr/Cr ratio, GGT and creatinine in the three sampling phases (P<0.05). However, no significant differences were observed between values for GGT/Cr ratio. There were significant differences between the mean values of creatinine, protein, GGT, and Pr/Cr ratio within pre-exercise and 1 hour post-exercise values and Pr/Cr ratio values in pre-exercise and 6 hours post-exercise (P<0.05).
Conclusions: It seems that a session of karate training does not result in permanent renal damage and for evaluation of tubular function, it is better to get the urine sample for urinary marker at least 6 hours after exercise.
