GI, Liver & Pancreas Pathology
Seyed Amir Miratashi Yazdi; Elham Nazar
Abstract
Background & Objective: Lymphovascular tumoral invasion is a typical histopathological feature of gastric carcinomas and supports the recognition of high-risk patients for the recurrence. We aimed to study the CD31 expression in diverse subtypes of gastric carcinomas and to show its association with ...
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Background & Objective: Lymphovascular tumoral invasion is a typical histopathological feature of gastric carcinomas and supports the recognition of high-risk patients for the recurrence. We aimed to study the CD31 expression in diverse subtypes of gastric carcinomas and to show its association with the histopathologic findings of the carcinoma to assess the prognosis.Methods: This cross-sectional study was conducted on 40 established patients of gastric adenocarcinoma from radical gastrectomy. The patients were classified according to the pathology assessments. Tumoral tissues were assessed by immunohistochemical staining for the CD31 expression. Malignant behavior was estimated by the histopathological evaluations.Results: CD31 positivity was described in 23 (57.5%) of all evaluated patients. The assessment of CD31 expression and tumor features presented no significant association between the CD31 expression and patients’ age, sex, tumor site, size, grade and stage, subtypes of carcinoma, perineural invasion, and also lymphovascular invasion (P>0.05).Conclusion: Lymphovascular invasion makes valuable additional evidence that might be useful to detect gastric carcinoma patients at high risk for the recurrence, who could be candidates for more supplementary therapies. However, in our society, the CD31 expression did not show any association with the aggressive histopathologic features of this tumor.
Bone & Soft tissue Pathology
Elham Nazar; Shabnam Mashadi; Golnaz Moradi
Abstract
Chondrosarcoma of the cranium is a rare malignancy. The result of treatment is challenging to assess because the slow-growing rate means that there is a long interval previously discovering the recurrence and last long time to diagnosis of recurrence. This report describes a 38-year-old man who presented ...
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Chondrosarcoma of the cranium is a rare malignancy. The result of treatment is challenging to assess because the slow-growing rate means that there is a long interval previously discovering the recurrence and last long time to diagnosis of recurrence. This report describes a 38-year-old man who presented with a generalized seizure 2 months before his referral. The patient underwent excisional surgery. The histological examinations revealed a cartilage developing tumor compatible with chondrosarcoma. The radiologic and histologic correlation established the diagnosis. But, the patient had two episodes of recurrence after surgery. We determined that intracranial chondrosarcoma must be comprised in the differential diagnosis of a mass with calcification on cranial imaging. Accurate diagnosis is obligatory for supplementary patient managing, and a recurrence is more common in patients only treated by surgery.
Amir Hosein Jafarian; Amin Rahpeyma; Saeedeh khajehahmadi
Abstract
The glandular odontogenic cyst (GOC) is a rare lesion with odontogenic origin. It shows a propensity for recurrence revealed in 30% of all case. This investigation reports a case of recurrent GOC in a 35-year-old female in the anterior region of the maxilla, which is uncommon and discusses about IHC ...
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The glandular odontogenic cyst (GOC) is a rare lesion with odontogenic origin. It shows a propensity for recurrence revealed in 30% of all case. This investigation reports a case of recurrent GOC in a 35-year-old female in the anterior region of the maxilla, which is uncommon and discusses about IHC finding, surgical methods, and differential diagnosis. Under general anesthesia, peripheral bone ostectomy via large round bur for removal of remaining epithelium of the cyst wall was done. Finally liquid nitrogen was used to remaining bone. This article recommends that soft tissue adjacent to the cortical bone perforation should be excised, as well as peripheral bone ostectomy by large round bur for removal of remaining epithelium of the cyst and liquid nitrogen application to the bony cavity. Because of high recurrence rate of the lesion close follow up of the patients is needed.
Nagarekha Kulkarni
Abstract
One of the unusual variant of ovarian tumor is sex cord stromal tumor with annular tubules (SCTAT). The recurrence in case of malignant ovarian SCTAT ranges from 3mo to 20yr. This report describes the case of recurrence of SCTAT in a 35yr old woman after 4yr of hysterectomy with bilateral salphingo-Oopherectomy. ...
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One of the unusual variant of ovarian tumor is sex cord stromal tumor with annular tubules (SCTAT). The recurrence in case of malignant ovarian SCTAT ranges from 3mo to 20yr. This report describes the case of recurrence of SCTAT in a 35yr old woman after 4yr of hysterectomy with bilateral salphingo-Oopherectomy. Microscopic examination revealed features of SCTAT. Because of its unusual behavior evidenced by delayed recurrence in spite of bland cellular features, proper long term follow–up is essential.
Nasim Taghavi; Abbas Khodayari; Soudabeh Sargolzaei; Fatemeh Mashhadiabbas; Mohammad Moshref; Ali Lotfi; Leili Mehrdad
Volume 4, Issue 3 , June 2009, , Pages 141-145
Abstract
Peripheral calcifying cystic odontogenic tumor (PCCOT) is a rare odontogenic lesion, which represents about 1% of jaw cysts. Here we report clinicopathologic, radiographic and CT scan images of a new case of recurrent large PCCOT located in mandibular gingiva in a 77-year-old male with history ...
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Peripheral calcifying cystic odontogenic tumor (PCCOT) is a rare odontogenic lesion, which represents about 1% of jaw cysts. Here we report clinicopathologic, radiographic and CT scan images of a new case of recurrent large PCCOT located in mandibular gingiva in a 77-year-old male with history of a nodular mass in the same area, which had been completely excised 3 years ago. In reviewing the literature, we found 55 previous reported cases with a mean age of 48.8 yr at the time of diagnosis. A majority of cases appear as a circumscribed nodule less than 1.5 cm in greatest diameter, without bony involvement. No case larger than 4cm in diameter has been reported. Only one case of recurrent PCCOT was seen in reported cases.
